Page last updated: 2024-10-30

mebendazole and Malaria

mebendazole has been researched along with Malaria in 7 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis."4.85Mebendazole in parasitic infections other than those caused by soil-transmitted helminths. ( Almirall, P; Brito, K; Cañete, R; Cimerman, S; Escobedo, AA; González, ME, 2009)
" vivax malaria attacks were treated with quinine or chloroquine plus primaquine."3.69Anaemia, iron deficiency and malaria in a rural community in Brazilian Amazon. ( Camargo, LM; Cardoso, MA; Ferreira, MU; Szarfarc, SC, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christian, P1
Shahid, F1
Rizvi, A1
Klemm, RD1
Bhutta, ZA1
Cañete, R1
Escobedo, AA1
Almirall, P1
González, ME1
Brito, K1
Cimerman, S1
Thwing, JI1
Perry, RT1
Townes, DA1
Diouf, MB1
Ndiaye, S1
Thior, M1
Larocque, R1
Casapia, M1
Gotuzzo, E1
MacLean, JD1
Soto, JC1
Rahme, E1
Gyorkos, TW1
Holzer, BR1
Egger, M1
Teuscher, T1
Koch, S1
Mboya, DM1
Smith, GD1
Cardoso, MA1
Ferreira, MU1
Camargo, LM1
Szarfarc, SC1
Campbell, WC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Anthelminthics and Multivitamins for Treatment of Severe Anemia in Pregnant Women and Children 6-24 Months of Age in Pakistan[NCT00116493]Phase 31,009 participants (Actual)Interventional2004-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for mebendazole and Malaria

ArticleYear
Mebendazole in parasitic infections other than those caused by soil-transmitted helminths.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:5

    Topics: Adolescent; Animals; Antiparasitic Agents; Child; Child, Preschool; Developing Countries; Dose-Respo

2009
The chemotherapy of parasitic infections.
    The Journal of parasitology, 1986, Volume: 72, Issue:1

    Topics: Amebiasis; Animals; Anthelmintics; Cattle; Cestode Infections; Cryptosporidiosis; Fascioliasis; Huma

1986

Trials

3 trials available for mebendazole and Malaria

ArticleYear
Treatment response to standard of care for severe anemia in pregnant women and effect of multivitamins and enhanced anthelminthics.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:3

    Topics: Adult; Anemia; Antinematodal Agents; Female; Folic Acid; Hemoglobins; Humans; Iron; Iron Deficiencie

2009
A double-blind randomized controlled trial of antenatal mebendazole to reduce low birthweight in a hookworm-endemic area of Peru.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:10

    Topics: Adult; Anemia; Antinematodal Agents; Double-Blind Method; Endemic Diseases; Female; Hookworm Infecti

2006
Childhood anemia in Africa: to transfuse or not transfuse?
    Acta tropica, 1993, Volume: 55, Issue:1-2

    Topics: Anemia; Blood Transfusion; Child, Preschool; Chloroquine; Hematocrit; HIV Infections; Hookworm Infec

1993

Other Studies

2 other studies available for mebendazole and Malaria

ArticleYear
Success of Senegal's first nationwide distribution of long-lasting insecticide-treated nets to children under five - contribution toward universal coverage.
    Malaria journal, 2011, Apr-13, Volume: 10

    Topics: Adult; Antimalarials; Child, Preschool; Cross-Sectional Studies; Female; Health Care Surveys; Health

2011
Anaemia, iron deficiency and malaria in a rural community in Brazilian Amazon.
    European journal of clinical nutrition, 1994, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Anemia, Hemolytic, Autoimmune; Anemia, Hypochromic; Animals; Brazil; Child; Child

1994