mebendazole has been researched along with Lung Neoplasms in 9 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In recent years, treatment of melanoma and a range of other deadly cancers has involved immunotherapy with programmed cell death protein-1 (PD-1)/PD-1 ligand (PD-L1) checkpoint blockade which has improved survival." | 5.51 | The anthelmintic flubendazole blocks human melanoma growth and metastasis and suppresses programmed cell death protein-1 and myeloid-derived suppressor cell accumulation. ( Acharya, G; Elahy, M; Khachigian, LM; Li, Y; Xin, H, 2019) |
| "Flubendazole may inhibit the proliferation of A549 and H460 cells and promote autophagy." | 1.56 | [Flubendazole Inhibits the Proliferation of A549 and H460 Cells and Promotes Autophagy]. ( Dong, T; Li, J; Liu, Y; Lu, Z; Wen, J, 2020) |
| "In recent years, treatment of melanoma and a range of other deadly cancers has involved immunotherapy with programmed cell death protein-1 (PD-1)/PD-1 ligand (PD-L1) checkpoint blockade which has improved survival." | 1.51 | The anthelmintic flubendazole blocks human melanoma growth and metastasis and suppresses programmed cell death protein-1 and myeloid-derived suppressor cell accumulation. ( Acharya, G; Elahy, M; Khachigian, LM; Li, Y; Xin, H, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, HS | 1 |
| Ko, YS | 1 |
| Jin, H | 1 |
| Kang, KM | 1 |
| Ha, IB | 1 |
| Jeong, H | 1 |
| Song, HN | 1 |
| Kim, HJ | 1 |
| Jeong, BK | 1 |
| Williamson, T | 1 |
| Mendes, TB | 1 |
| Joe, N | 1 |
| Cerutti, JM | 1 |
| Riggins, GJ | 1 |
| Coyne, CP | 1 |
| Narayanan, L | 1 |
| Dong, T | 1 |
| Lu, Z | 1 |
| Li, J | 1 |
| Liu, Y | 1 |
| Wen, J | 1 |
| Li, Y | 1 |
| Acharya, G | 1 |
| Elahy, M | 1 |
| Xin, H | 1 |
| Khachigian, LM | 1 |
| Mukhopadhyay, T | 2 |
| Sasaki, J | 2 |
| Ramesh, R | 2 |
| Roth, JA | 2 |
| Chada, S | 1 |
| Gomyo, Y | 1 |
| Löscher, T | 1 |
| Stürmer, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas[NCT01837862] | Phase 1/Phase 2 | 36 participants (Anticipated) | Interventional | 2013-10-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for mebendazole and Lung Neoplasms
| Article | Year |
|---|---|
Anticancer Effect of Benzimidazole Derivatives, Especially Mebendazole, on Triple-Negative Breast Cancer (TNBC) and Radiotherapy-Resistant TNBC In Vivo and In Vitro.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Biomarkers, Tumor; Cell Cycle Checkpoints; Cell Line | 2021 |
Mebendazole inhibits tumor growth and prevents lung metastasis in models of advanced thyroid cancer.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neopl | 2020 |
Mebendazole in simultaneous combination with dexamethasone-(C
Topics: Adenocarcinoma of Lung; Amides; Antineoplastic Agents; Dexamethasone; ErbB Receptors; Humans; Lung N | 2019 |
[Flubendazole Inhibits the Proliferation of A549 and H460 Cells and Promotes Autophagy].
Topics: A549 Cells; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; G | 2020 |
The anthelmintic flubendazole blocks human melanoma growth and metastasis and suppresses programmed cell death protein-1 and myeloid-derived suppressor cell accumulation.
Topics: Animals; Antinematodal Agents; Antineoplastic Agents; Cell Growth Processes; Cell Line, Tumor; Femal | 2019 |
Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; | 2002 |
The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.
Topics: Administration, Oral; Animals; Antinematodal Agents; Antineoplastic Agents, Phytogenic; Apoptosis; B | 2002 |
[Echinococcosis].
Topics: Adult; Diagnosis, Differential; Echinococcosis, Pulmonary; Female; Humans; Lung Neoplasms; Mebendazo | 1979 |
[A case from practice (117). Patient: Mr. A. K., born 1962, asylum seeker].
Topics: Adult; Diagnosis, Differential; Echinococcosis, Hepatic; Echinococcosis, Pulmonary; Humans; Lung Neo | 1988 |