mebendazole has been researched along with Loiasis in 9 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Loiasis: A parasitic infection caused by the nematode Loa loa. The vector in the transmission of this infection is the horsefly (Tabanus) or the deerfly or mango fly (Chrysops). The larvae may be seen just beneath the skin or passing through the conjunctiva. Eye lesions are not uncommon. The disease is generally mild and painless.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of mebendazole as a microfilaricide in patients with loiasis was studied." | 9.06 | Failure of high dose mebendazole as a microfilaricide in patients with loiasis. ( Burchard, GD; Kern, P, 1987) |
| "Mebendazole (Vermox 500) in long duration treatment 2 g/day for 3 to 4 weeks, is sometimes indicated in therapy of Loa Loa filariasis but remains the only active therapy on M." | 7.67 | [Filariasis in Gabon: treatment with mebendazole of filariasis due to M. perstans and Loa loa]. ( Burnier, I; Kombila, M; Maganga, ML; Richard-Lenoble, D, 1985) |
| "Flubendazole (FLBZ) is a potent and efficacious macrofilaricide after parenteral administration." | 5.48 | Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity. ( Burkman, E; Dzimianski, M; Geary, TG; Kengne-Ouafo, JA; Mackenzie, CD; Moorhead, A; Ndongmo, PC; Njouendou, JA; O'Neill, M; Wanji, S, 2018) |
| "Treatment with mebendazole (1." | 5.27 | Treatment of recurrent, filarial, Calabar-type oedema with mebendazole. ( Flocard, F; Van Hoegaerden, M, 1986) |
| "The effectiveness of mebendazole as a microfilaricide in patients with loiasis was studied." | 5.06 | Failure of high dose mebendazole as a microfilaricide in patients with loiasis. ( Burchard, GD; Kern, P, 1987) |
| "Mebendazole (Vermox 500) in long duration treatment 2 g/day for 3 to 4 weeks, is sometimes indicated in therapy of Loa Loa filariasis but remains the only active therapy on M." | 3.67 | [Filariasis in Gabon: treatment with mebendazole of filariasis due to M. perstans and Loa loa]. ( Burnier, I; Kombila, M; Maganga, ML; Richard-Lenoble, D, 1985) |
| "loa L3 and treated with 10 mg/kg FLBZ once daily for 5 consecutive days." | 1.51 | Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents. ( Chunda, VC; Enyong, P; Fombad, FF; Gandjui, NVT; Hoerauf, A; Mackenzie, CD; Metuge, HM; Ndongmo, PC; Njiokou, F; Njouendou, AJ; Ritter, M; Wanji, S, 2019) |
| "Flubendazole (FLBZ) is a potent and efficacious macrofilaricide after parenteral administration." | 1.48 | Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity. ( Burkman, E; Dzimianski, M; Geary, TG; Kengne-Ouafo, JA; Mackenzie, CD; Moorhead, A; Ndongmo, PC; Njouendou, JA; O'Neill, M; Wanji, S, 2018) |
| "Treatment with mebendazole (1." | 1.27 | Treatment of recurrent, filarial, Calabar-type oedema with mebendazole. ( Flocard, F; Van Hoegaerden, M, 1986) |
| "Patients harbouring Loa loa and/or Mansonella perstans infections, or presenting typical filarial symptomatology, were treated with mebendazole, a drug shown to be efficient in other parasitoses." | 1.27 | The use of mebendazole in the treatment of filariases due to Loa loa and Mansonella perstans. ( Chabaud, B; Flocard, F; Ivanoff, B; Salle, A; Van Hoegaerden, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Neill, M | 1 |
| Njouendou, JA | 1 |
| Dzimianski, M | 1 |
| Burkman, E | 1 |
| Ndongmo, PC | 2 |
| Kengne-Ouafo, JA | 1 |
| Wanji, S | 2 |
| Moorhead, A | 1 |
| Mackenzie, CD | 2 |
| Geary, TG | 1 |
| Fombad, FF | 1 |
| Njouendou, AJ | 1 |
| Ritter, M | 1 |
| Chunda, VC | 1 |
| Metuge, HM | 1 |
| Gandjui, NVT | 1 |
| Enyong, P | 1 |
| Njiokou, F | 1 |
| Hoerauf, A | 1 |
| Moliner, JV | 1 |
| Valverde, AG | 1 |
| Sorolla, JM | 1 |
| Kamgno, J | 1 |
| Boussinesq, M | 1 |
| Van Hoegaerden, M | 3 |
| Flocard, F | 3 |
| Burchard, GD | 1 |
| Kern, P | 1 |
| Ivanoff, B | 1 |
| Salle, A | 1 |
| Chabaud, B | 1 |
| Richard-Lenoble, D | 1 |
| Kombila, M | 1 |
| Burnier, I | 1 |
| Maganga, ML | 1 |
2 trials available for mebendazole and Loiasis
| Article | Year |
|---|---|
Effect of a single dose (600 mg) of albendazole on Loa loa microfilaraemia.
Topics: Adolescent; Adult; Albendazole; Animals; Child; Dietary Fats; Female; Filaricides; Humans; Loa; Loia | 2002 |
Failure of high dose mebendazole as a microfilaricide in patients with loiasis.
Topics: Clinical Trials as Topic; Filariasis; Humans; Loiasis; Mebendazole | 1987 |
7 other studies available for mebendazole and Loiasis
| Article | Year |
|---|---|
Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity.
Topics: Animals; Brugia malayi; Culicidae; Filariasis; Filaricides; Humans; Loa; Loiasis; Mebendazole; Micro | 2018 |
Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents.
Topics: Africa, Central; Africa, Western; Animals; Cell Line; Elephantiasis, Filarial; Filaricides; Hydrolys | 2019 |
[Loa loa meningoencephalitis secondary to treatment with mebendazol].
Topics: Adolescent; Albendazole; Animals; Anthelmintics; Brain Damage, Chronic; Central Nervous System Helmi | 2011 |
Mebendazole treatment of loaiasis.
Topics: Benzimidazoles; Diethylcarbamazine; Filariasis; Humans; Loiasis; Mebendazole | 1985 |
Treatment of recurrent, filarial, Calabar-type oedema with mebendazole.
Topics: Adult; Dipetalonema Infections; Edema; Filariasis; Gabon; Humans; Loa; Loiasis; Male; Mebendazole; R | 1986 |
The use of mebendazole in the treatment of filariases due to Loa loa and Mansonella perstans.
Topics: Adolescent; Adult; Animals; Filariasis; Humans; Loiasis; Mansonelliasis; Mebendazole; Microfilariae; | 1987 |
[Filariasis in Gabon: treatment with mebendazole of filariasis due to M. perstans and Loa loa].
Topics: Filariasis; Gabon; Humans; Loiasis; Mansonelliasis; Mebendazole | 1985 |