Page last updated: 2024-10-30

mebendazole and Haemonchiasis

mebendazole has been researched along with Haemonchiasis in 17 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Haemonchiasis: Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.

Research Excerpts

ExcerptRelevanceReference
"Thiabendazole was used more often (9 tests) than the other compounds."2.67Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962. ( Drudge, JH; Lyons, ET; Stamper, S; Tolliver, SC, 1993)
"Closantel was highly effective against H."1.29Control of haemonchosis in Malaysian goats with closantel. ( Dorny, P; Jalila, A; Sani, R; Symoens, C; Vercruysse, J, 1994)
" In the latter case, control was achieved by dosing either the ewes in the early part of the grazing season, or the lambs from June onwards."1.28Effectiveness of strategic anthelmintic dosing in controlling Haemonchus contortus infections in sheep in the United Kingdom. ( Hunt, KR; Quick, JM; Taylor, MA; Wilson, CA, 1991)
"Fenbendazole was more effective against both strains following intra-ruminal administration."1.26The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole. ( Campbell, NJ; Hall, CA; Kelly, JD; Martin, IC; Thompson, HG; Whitlock, HV, 1977)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's6 (35.29)18.2507
2000's3 (17.65)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stuchlíková, LR1
Matoušková, P1
Vokřál, I2
Lamka, J4
Szotáková, B4
Sečkařová, A1
Dimunová, D1
Nguyen, LT1
Várady, M3
Skálová, L4
Bártíková, H2
Krízová, V2
Kubícek, V3
Prchal, L1
Stuchlíková, L1
Garg, R1
Kumar, RR1
Yadav, CL2
Banerjee, PS1
Cvilink, V1
Nobilis, M1
Kubenová, M1
Novotná, R1
Gavelová, M1
Bryant, C2
Bennet, EM1
Chevis, RA2
Rahman, WA1
Dorny, P1
Vercruysse, J1
Jalila, A1
Sani, R1
Symoens, C1
Lyons, ET1
Drudge, JH1
Tolliver, SC1
Stamper, S1
Kumar, R1
Uppal, RP1
Verma, SP1
Oxberry, ME1
Gear, TG1
Prichard, RK1
Rahman, MS1
Cornish, RA1
Zajícek, D1
Márová, M1
Zahradníková, W1
Kelly, JD1
Hall, CA1
Whitlock, HV1
Thompson, HG1
Campbell, NJ1
Martin, IC1
Taylor, MA2
Hunt, KR2
Wilson, CA2
Quick, JM2

Trials

3 trials available for mebendazole and Haemonchiasis

ArticleYear
Flubendazole metabolism and biotransformation enzymes activities in healthy sheep and sheep with haemonchosis.
    Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:1

    Topics: Animals; Biotransformation; Haemonchiasis; Haemonchus; Liver; Male; Mebendazole; Sheep; Sheep Diseas

2010
Duration of anthelmintic effect of three formulations of ivermectin (oral, injectable and pour-on) against multiple anthelmintic-resistant haemonchus contortus in sheep.
    Veterinary research communications, 2007, Volume: 31, Issue:6

    Topics: Administration, Oral; Administration, Topical; Albendazole; Animals; Anthelmintics; Drug Resistance,

2007
Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962.
    American journal of veterinary research, 1993, Volume: 54, Issue:3

    Topics: Aging; Animals; Anthelmintics; Benzimidazoles; Cambendazole; Drug Combinations; Fenbendazole; Haemon

1993

Other Studies

14 other studies available for mebendazole and Haemonchiasis

ArticleYear
Metabolism of albendazole, ricobendazole and flubendazole in Haemonchus contortus adults: Sex differences, resistance-related differences and the identification of new metabolites.
    International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Biochemical Phenomena; Biotransformation; Drug Resistance; Fema

2018
The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics.
    Parasitology, 2012, Volume: 139, Issue:10

    Topics: Animals; Anthelmintics; Drug Resistance; Haemonchiasis; Haemonchus; Mebendazole; Sheep; Sheep Diseas

2012
Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus.
    Veterinary parasitology, 2008, Feb-14, Volume: 151, Issue:2-4

    Topics: Animals; Biotransformation; Haemonchiasis; Haemonchus; Mebendazole; Oxidoreductases; Sheep; Sheep Di

2008
Observations on the fumarate reductase system in Haemonchus contortus and their relevance to anthelmintic resistance and to strain variations of energy metabolism.
    Molecular and biochemical parasitology, 1983, Volume: 7, Issue:4

    Topics: Animals; Benzimidazoles; Cambendazole; Drug Resistance, Microbial; Energy Metabolism; Haemonchiasis;

1983
The speed of action of anthelmintics: mebendazole.
    The Veterinary record, 1980, Oct-25, Volume: 107, Issue:17

    Topics: Animals; Benzimidazoles; Digestive System; Fascioliasis; Haemonchiasis; Mebendazole; Monieziasis; Sh

1980
Resistance to benzimidazole anthelmintics by Haemonchus contortus in goats in peninsular Malaysia.
    Veterinary parasitology, 1994, Volume: 55, Issue:1-2

    Topics: Albendazole; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Fenbendazole; Goat Diseases; G

1994
Control of haemonchosis in Malaysian goats with closantel.
    Veterinary parasitology, 1994, Volume: 53, Issue:3-4

    Topics: Administration, Oral; Animals; Anthelmintics; Feces; Female; Goat Diseases; Goats; Haemonchiasis; In

1994
Multiple anthelmintic resistance in Haemonchus contortus on a sheep farm in India.
    Veterinary parasitology, 1995, Volume: 60, Issue:3-4

    Topics: Albendazole; Animal Husbandry; Animals; Anthelmintics; Benzimidazoles; Drug Resistance, Multiple; Fe

1995
Assessment of benzimidazole binding to individual recombinant tubulin isotypes from Haemonchus contortus.
    Parasitology, 2001, Volume: 122, Issue:Pt 6

    Topics: Animals; Anthelmintics; Binding Sites; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Esche

2001
Metabolic changes in some helminths from sheep treated with mebendazole.
    New Zealand veterinary journal, 1977, Volume: 25, Issue:4

    Topics: Animals; Benzimidazoles; Candidiasis; Cestoda; Fasciola; Fascioliasis; Haemonchiasis; Haemonchus; He

1977
[Efficacy of mebendazole in sheep experimentally invaded with larvae of Haemonchus contortus and Trichostrongylus colubriformis in relation to the results of clinical examination].
    Veterinarni medicina, 1978, Volume: 23, Issue:1

    Topics: Animals; Benzimidazoles; Disease Models, Animal; Haemonchiasis; Mebendazole; Sheep; Sheep Diseases;

1978
The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole.
    Research in veterinary science, 1977, Volume: 22, Issue:2

    Topics: Abomasum; Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Female; Fen

1977
Effectiveness of strategic anthelmintic dosing in controlling Haemonchus contortus infections in sheep in the United Kingdom.
    The Veterinary record, 1991, Aug-31, Volume: 129, Issue:9

    Topics: Animals; Anthelmintics; Drug Therapy, Combination; Feces; Female; Haemonchiasis; Levamisole; Mebenda

1991
Clinical observations, diagnosis and control of H contortus infections in periparturient ewes.
    The Veterinary record, 1990, Jun-02, Volume: 126, Issue:22

    Topics: Animals; Female; Haemonchiasis; Haemonchus; Hematocrit; Mebendazole; Parasite Egg Count; Pregnancy;

1990