mebendazole has been researched along with Glioma in 3 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to evaluate the in vitro chemosensitivity of three canine glioma cell lines to mebendazole and fenbendazole." | 7.85 | In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells. ( Castello, SA; Koehler, JW; Lai, SR; Robinson, AC, 2017) |
| " The purpose of this study was to evaluate the in vitro chemosensitivity of three canine glioma cell lines to mebendazole and fenbendazole." | 3.85 | In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells. ( Castello, SA; Koehler, JW; Lai, SR; Robinson, AC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Meco, D | 1 |
| Attinà , G | 1 |
| Mastrangelo, S | 1 |
| Navarra, P | 1 |
| Ruggiero, A | 1 |
| Kipper, FC | 1 |
| Silva, AO | 1 |
| Marc, AL | 1 |
| Confortin, G | 1 |
| Junqueira, AV | 1 |
| Neto, EP | 1 |
| Lenz, G | 1 |
| Lai, SR | 1 |
| Castello, SA | 1 |
| Robinson, AC | 1 |
| Koehler, JW | 1 |
1 review available for mebendazole and Glioma
| Article | Year |
|---|---|
Emerging Perspectives on the Antiparasitic Mebendazole as a Repurposed Drug for the Treatment of Brain Cancers.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Antiparasitic Agents; Brain Neoplasms; Cell L | 2023 |
2 other studies available for mebendazole and Glioma
| Article | Year |
|---|---|
Vinblastine and antihelmintic mebendazole potentiate temozolomide in resistant gliomas.
Topics: Anthelmintics; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; Drug Resistance, Neopl | 2018 |
In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Dog Diseases; Dogs; Fenbendazole; Glioma; Male; Mebend | 2017 |