mebendazole has been researched along with Giardiasis in 26 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Giardiasis: An infection of the SMALL INTESTINE caused by the flagellated protozoan GIARDIA. It is spread via contaminated food and water and by direct person-to-person contact.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy and safety of five days apostrophe therapy of mebendazole (MBZ) versus quinacrine (QC) on human giardiasis in children." | 9.12 | Randomized clinical study of five days apostrophe therapy with mebendazole compared to quinacrine in the treatment of symptomatic giardiasis in children. ( Almirall, P; Canete, R; Escobedo, AA; Gonzalez, ME, 2006) |
| "To compare the efficacy and safety of mebendazole versus tinidazole in the treatment of giardiasis." | 9.12 | A randomized, controlled, open-label trial of a single day of mebendazole versus a single dose of tinidazole in the treatment of giardiasis in children. ( Almirall, P; Cañete, R; Cantelar, N; Escobedo, AA; González, ME, 2006) |
| "To compare the efficacy of the two drugs in the treatment of giardiasis, 146 children (aged 5-15 years) with confirmed Giardia lamblia infection were randomly allotted to treatment with mebendazole (200 mg three times daily for 3 days) or secnidazole (30 mg/kg, in a single dose)." | 9.10 | A randomized trial comparing mebendazole and secnidazole for the treatment of giardiasis. ( Almirall, P; Cañete, R; Cimerman, S; Escobedo, AA; Gonzalez, ME; Pareja, A, 2003) |
| "Mebendazole (MBZ), a benzimidazole compound, has received attention in treating patients with giardiasis because it has shown beneficial effects both in vitro and in vivo." | 8.98 | Efficacy of mebendazole in paediatric patients with giardiasis: A systematic review and meta-analysis. ( Almirall, P; Ballesteros, J; Escobedo, AA; González-Fraile, E, 2018) |
| "To evaluate the effectiveness and tolerability of secnidazole combined with high-dose mebendazole for treatment of 5-nitroimidazole-resistant giardiasis." | 7.96 | 5-Nitroimidazole refractory giardiasis is common in Matanzas, Cuba and effectively treated by secnidazole plus high-dose mebendazole or quinacrine: a prospective observational cohort study. ( Brito, K; Cañete, R; Herrera, E; Kofoed, PE; Noda, AL; Rodríguez, M; Ursing, J, 2020) |
| "Application of a single drug for treatment of both giardiasis and soil-transmitted helminthosis is highly desirable." | 6.70 | Comparative clinical trial of mebendazole and metronidazole in giardiasis of children. ( Alborzi, AW; Mostovfi, H; Sadjjadi, SM, 2001) |
| "To compare the efficacy and safety of five days apostrophe therapy of mebendazole (MBZ) versus quinacrine (QC) on human giardiasis in children." | 5.12 | Randomized clinical study of five days apostrophe therapy with mebendazole compared to quinacrine in the treatment of symptomatic giardiasis in children. ( Almirall, P; Canete, R; Escobedo, AA; Gonzalez, ME, 2006) |
| "To compare the efficacy and safety of mebendazole versus tinidazole in the treatment of giardiasis." | 5.12 | A randomized, controlled, open-label trial of a single day of mebendazole versus a single dose of tinidazole in the treatment of giardiasis in children. ( Almirall, P; Cañete, R; Cantelar, N; Escobedo, AA; González, ME, 2006) |
| "To compare the efficacy of the two drugs in the treatment of giardiasis, 146 children (aged 5-15 years) with confirmed Giardia lamblia infection were randomly allotted to treatment with mebendazole (200 mg three times daily for 3 days) or secnidazole (30 mg/kg, in a single dose)." | 5.10 | A randomized trial comparing mebendazole and secnidazole for the treatment of giardiasis. ( Almirall, P; Cañete, R; Cimerman, S; Escobedo, AA; Gonzalez, ME; Pareja, A, 2003) |
| " Further research into more recent clinical isolates is necessary to uncover mechanisms for the increase in metronidazole refractory giardiasis observed during the last decade." | 5.05 | Giardiasis treatment: an update with a focus on refractory disease. ( Hanevik, K; Mørch, K, 2020) |
| "Mebendazole (MBZ), a benzimidazole compound, has received attention in treating patients with giardiasis because it has shown beneficial effects both in vitro and in vivo." | 4.98 | Efficacy of mebendazole in paediatric patients with giardiasis: A systematic review and meta-analysis. ( Almirall, P; Ballesteros, J; Escobedo, AA; González-Fraile, E, 2018) |
| "Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis." | 4.85 | Mebendazole in parasitic infections other than those caused by soil-transmitted helminths. ( Almirall, P; Brito, K; Cañete, R; Cimerman, S; Escobedo, AA; González, ME, 2009) |
| "To evaluate the effectiveness and tolerability of secnidazole combined with high-dose mebendazole for treatment of 5-nitroimidazole-resistant giardiasis." | 3.96 | 5-Nitroimidazole refractory giardiasis is common in Matanzas, Cuba and effectively treated by secnidazole plus high-dose mebendazole or quinacrine: a prospective observational cohort study. ( Brito, K; Cañete, R; Herrera, E; Kofoed, PE; Noda, AL; Rodríguez, M; Ursing, J, 2020) |
| "Treatment (mebendazole) or placebo tablets were administered every 2 mo for 8 mo and again at 12 mo." | 2.70 | Anthelmintic treatment of rural Bangladeshi children: effect on host physiology, growth, and biochemical status. ( Lunn, PG; Mascie-Taylor, CN; Northrop-Clewes, CA; Rousham, EK, 2001) |
| "Application of a single drug for treatment of both giardiasis and soil-transmitted helminthosis is highly desirable." | 2.70 | Comparative clinical trial of mebendazole and metronidazole in giardiasis of children. ( Alborzi, AW; Mostovfi, H; Sadjjadi, SM, 2001) |
| "Endemic parasitic infections in the United States are more frequent than is commonly perceived." | 2.49 | Childhood parasitic infections endemic to the United States. ( Barry, MA; Hotez, PJ; Weatherhead, JE; Woc-Colburn, L, 2013) |
| "Albendazole probably has fewer side effects than metronidazole (gastrointestinal side effects: RR 0." | 2.48 | Drugs for treating giardiasis. ( Criollo, CP; Granados, CE; Reveiz, L; Uribe, LG, 2012) |
| " All samples underwent visual and physical inspection for labeling and packaging before physico-chemical quality testing and evaluated based on individual monographs in Pharmacopoeias for identification, assay/content, dosage uniformity, dissolution, disintegration and friability." | 1.40 | Quality of medicines commonly used in the treatment of soil transmitted helminths and giardia in ethiopia: a nationwide survey. ( D'Hondt, M; De Spiegeleer, B; Deti, H; Duchateau, L; Levecke, B; Mekonnen, Z; Suleman, S; Vercruysse, J; Wynendaele, E; Zeleke, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.54) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Riches, A | 1 |
| Hart, CJS | 1 |
| Trenholme, KR | 1 |
| Skinner-Adams, TS | 1 |
| Cañete, R | 6 |
| Noda, AL | 1 |
| Rodríguez, M | 1 |
| Brito, K | 2 |
| Herrera, E | 1 |
| Kofoed, PE | 1 |
| Ursing, J | 1 |
| Mørch, K | 1 |
| Hanevik, K | 1 |
| Escobedo, AA | 6 |
| Almirall, P | 6 |
| González-Fraile, E | 1 |
| Ballesteros, J | 1 |
| Barry, MA | 1 |
| Weatherhead, JE | 1 |
| Hotez, PJ | 1 |
| Woc-Colburn, L | 1 |
| Suleman, S | 1 |
| Zeleke, G | 1 |
| Deti, H | 1 |
| Mekonnen, Z | 1 |
| Duchateau, L | 1 |
| Levecke, B | 1 |
| Vercruysse, J | 1 |
| D'Hondt, M | 1 |
| Wynendaele, E | 1 |
| De Spiegeleer, B | 1 |
| González, ME | 4 |
| Cimerman, S | 3 |
| Cortizo-Vidal, S | 1 |
| Rodríguez-Otero, LM | 1 |
| Villamil-Cajoto, I | 1 |
| Llovo-Taboada, J | 1 |
| Moore, CE | 1 |
| Hor, PC | 1 |
| Soeng, S | 1 |
| Sun, S | 1 |
| Lee, SJ | 1 |
| Parry, CM | 1 |
| Day, NP | 1 |
| Stoesser, N | 1 |
| Granados, CE | 1 |
| Reveiz, L | 1 |
| Uribe, LG | 1 |
| Criollo, CP | 1 |
| Pareja, A | 1 |
| Cantelar, N | 1 |
| Kiser, JD | 1 |
| Paulson, CP | 1 |
| Brown, C | 1 |
| Rousham, EK | 2 |
| Bulut, BU | 1 |
| Gülnar, SB | 1 |
| Aysev, D | 1 |
| Northrop-Clewes, CA | 1 |
| Mascie-Taylor, CN | 1 |
| Lunn, PG | 1 |
| Sadjjadi, SM | 1 |
| Alborzi, AW | 1 |
| Mostovfi, H | 1 |
| Diouf, S | 1 |
| Diagne, I | 1 |
| Moreira, C | 1 |
| Signate, SY | 1 |
| Faye, O | 1 |
| Ndiaye, O | 1 |
| Sylla, A | 1 |
| Diallo, I | 1 |
| Thiam, D | 1 |
| Diop, B | 1 |
| Thiam, I | 1 |
| Gaye, I | 1 |
| Sarr, M | 1 |
| Fall, M | 1 |
| Botero, D | 1 |
| Hutchison, JG | 1 |
| Johnston, NM | 1 |
| Plevey, MV | 1 |
| Thangkhiew, I | 1 |
| Aidney, C | 1 |
| al-Waili, NS | 2 |
| Hasan, NU | 1 |
| Köksal, I | 1 |
| Malkoç, CH | 1 |
| Ozergin, O | 1 |
| Düğdü, S | 1 |
| Ozgürbüz, F | 1 |
| Cakmak, T | 1 |
| Beşer, E | 1 |
| al-Waili, BH | 1 |
| Saloom, KY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in School Children in Southern Vietnam[NCT02597556] | Phase 4 | 0 participants (Actual) | Interventional | 2016-02-29 | Withdrawn (stopped due to The prevalence of worm infections in the site is significantly lower than expected) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for mebendazole and Giardiasis
| Article | Year |
|---|---|
Anti-
Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Drug Delivery Systems; Drug Discovery; Drug Therapy, | 2020 |
Giardiasis treatment: an update with a focus on refractory disease.
Topics: Adult; Albendazole; Antiprotozoal Agents; Benzimidazoles; Child; Diarrhea; Drug Resistance; Drug The | 2020 |
Efficacy of mebendazole in paediatric patients with giardiasis: A systematic review and meta-analysis.
Topics: Antinematodal Agents; Child; Giardiasis; Humans; Mebendazole | 2018 |
Childhood parasitic infections endemic to the United States.
Topics: Albendazole; Antiparasitic Agents; Black or African American; Chagas Disease; Child; Child, Preschoo | 2013 |
Mebendazole in parasitic infections other than those caused by soil-transmitted helminths.
Topics: Adolescent; Animals; Antiparasitic Agents; Child; Child, Preschool; Developing Countries; Dose-Respo | 2009 |
Drugs for treating giardiasis.
Topics: Adult; Albendazole; Antiparasitic Agents; Child; Giardiasis; Humans; Mebendazole; Metronidazole; Nit | 2012 |
Clinical inquiries. What's the most effective treatment for giardiasis?
Topics: Albendazole; Antinematodal Agents; Antitrichomonal Agents; Giardiasis; Humans; Mebendazole; Metronid | 2008 |
Chemotherapy of human intestinal parasitic diseases.
Topics: Amebiasis; Amides; Ancylostomiasis; Ascariasis; Bephenium Compounds; Cestode Infections; Emetine; Fu | 1978 |
8 trials available for mebendazole and Giardiasis
| Article | Year |
|---|---|
A randomized trial comparing mebendazole and secnidazole for the treatment of giardiasis.
Topics: Adolescent; Antiprotozoal Agents; Child; Child, Preschool; Feces; Female; Giardiasis; Humans; Male; | 2003 |
Randomized clinical study of five days apostrophe therapy with mebendazole compared to quinacrine in the treatment of symptomatic giardiasis in children.
Topics: Adolescent; Animals; Antinematodal Agents; Child; Child, Preschool; Cuba; Dose-Response Relationship | 2006 |
A randomized, controlled, open-label trial of a single day of mebendazole versus a single dose of tinidazole in the treatment of giardiasis in children.
Topics: Adolescent; Antiprotozoal Agents; Child; Drug Administration Schedule; Feces; Female; Giardiasis; Hu | 2006 |
An increase in Giardia duodenalis infection among children receiving periodic Anthelmintic treatment in Bangladesh.
Topics: Animals; Bangladesh; Chi-Square Distribution; Child; Child, Preschool; Drug Administration Schedule; | 1994 |
Alternative treatment protocols in giardiasis: a pilot study.
Topics: Adolescent; Animals; Antiprotozoal Agents; Child; Drug Administration Schedule; Feces; Female; Giard | 1996 |
Anthelmintic treatment of rural Bangladeshi children: effect on host physiology, growth, and biochemical status.
Topics: Animals; Anthelmintics; Anthropometry; Ascariasis; Ascaris lumbricoides; Bangladesh; Child Developme | 2001 |
Comparative clinical trial of mebendazole and metronidazole in giardiasis of children.
Topics: Animals; Anti-Infective Agents; Antinematodal Agents; Child; Female; Giardia lamblia; Giardiasis; Hu | 2001 |
Mebendazole in giardial infection: a comparative study with metronidazole.
Topics: Adolescent; Animals; Child; Child, Preschool; Female; Giardiasis; Humans; Male; Mebendazole; Metroni | 1992 |
10 other studies available for mebendazole and Giardiasis
| Article | Year |
|---|---|
5-Nitroimidazole refractory giardiasis is common in Matanzas, Cuba and effectively treated by secnidazole plus high-dose mebendazole or quinacrine: a prospective observational cohort study.
Topics: Adult; Aged; Antiprotozoal Agents; Cuba; Drug Administration Schedule; Drug Resistance; Drug Therapy | 2020 |
Mebendazole as an alternative in Giardia duodenalis infection.
Topics: Antiparasitic Agents; Giardia lamblia; Giardiasis; Humans; Mebendazole | 2013 |
Quality of medicines commonly used in the treatment of soil transmitted helminths and giardia in ethiopia: a nationwide survey.
Topics: Albendazole; Animals; Anthelmintics; Ethiopia; Giardiasis; Helminthiasis; Humans; Mebendazole; Preva | 2014 |
[Eosinophilia in an adopted native Ethiopian girl].
Topics: Adoption; Amebiasis; Animals; Anthelmintics; Antiprotozoal Agents; Blastocystis hominis; Blastocysti | 2010 |
An old drug against giardiasis: mebendazole as a treatment option.
Topics: Adolescent; Adult; Antiprotozoal Agents; Child; Child, Preschool; Giardia lamblia; Giardiasis; Human | 2011 |
Changing patterns of gastrointestinal parasite infections in Cambodian children: 2006-2011.
Topics: Ancylostomatoidea; Animals; Antinematodal Agents; Asian People; Cambodia; Child, Preschool; Feces; F | 2012 |
[Integrated treatment of iron deficiency, vitamin A deficiency and intestinal parasitic diseases: impact on Senegalese children's growth].
Topics: Anemia, Iron-Deficiency; Anti-Infective Agents; Antinematodal Agents; Child Nutrition Disorders; Chi | 2002 |
Clinical trial of mebendazole, a broad-spectrum anthelminthic.
Topics: Adolescent; Anthelmintics; Ascariasis; Benzimidazoles; Child; Female; Giardiasis; Helminthiasis; Hoo | 1975 |
[The prevalence of intestinal parasites in primary school students in Trabzon and the importance of education of parasite patients].
Topics: Ascariasis; Child; Feces; Giardiasis; Health Education; Humans; Intestinal Diseases, Parasitic; Mebe | 1992 |
Therapeutic use of mebendazole in giardial infections.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Giardiasis; Humans; Intestinal Diseases, Parasit | 1988 |