mebendazole has been researched along with Elaeophoriasis in 43 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of mebendazole as a microfilaricide in patients with loiasis was studied." | 9.06 | Failure of high dose mebendazole as a microfilaricide in patients with loiasis. ( Burchard, GD; Kern, P, 1987) |
| "Mebendazole (Vermox 500) in long duration treatment 2 g/day for 3 to 4 weeks, is sometimes indicated in therapy of Loa Loa filariasis but remains the only active therapy on M." | 7.67 | [Filariasis in Gabon: treatment with mebendazole of filariasis due to M. perstans and Loa loa]. ( Burnier, I; Kombila, M; Maganga, ML; Richard-Lenoble, D, 1985) |
| "Flubendazole (FLBZ) is a potent and efficacious macrofilaricide after parenteral administration." | 5.48 | Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity. ( Burkman, E; Dzimianski, M; Geary, TG; Kengne-Ouafo, JA; Mackenzie, CD; Moorhead, A; Ndongmo, PC; Njouendou, JA; O'Neill, M; Wanji, S, 2018) |
| "Treatment with mebendazole (1." | 5.27 | Treatment of recurrent, filarial, Calabar-type oedema with mebendazole. ( Flocard, F; Van Hoegaerden, M, 1986) |
| "The effectiveness of mebendazole as a microfilaricide in patients with loiasis was studied." | 5.06 | Failure of high dose mebendazole as a microfilaricide in patients with loiasis. ( Burchard, GD; Kern, P, 1987) |
| "Mebendazole (Vermox 500) in long duration treatment 2 g/day for 3 to 4 weeks, is sometimes indicated in therapy of Loa Loa filariasis but remains the only active therapy on M." | 3.67 | [Filariasis in Gabon: treatment with mebendazole of filariasis due to M. perstans and Loa loa]. ( Burnier, I; Kombila, M; Maganga, ML; Richard-Lenoble, D, 1985) |
| " Levamisole at a dosage of 3 mg/kg daily for 8 days showed marked reduction in both microfilaria rate and microfilaria density and immediately thereafter mf-rate steadily increased almost up to pre-treatment level, the mf-density however showed only marginal increase." | 2.64 | Levamisole and mebendazole in the treatment of bancroftian infection. ( Das, M; Narasimham, MV; Rao, CK; Roychowdhury, SP, 1978) |
| " In summary, oral doses of ASD formulated FBZ did not significantly reduce total worm burden but longer treatments, extended takedown times or a second dosing regimen, may decrease female fecundity and the number of mf shed by female worms." | 1.51 | Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugia pahangi. ( Baeten, B; Beerntsen, B; Bulman, CA; Engelen, M; Fischer, C; Gut, J; Ibiricu Urriza, I; Lachau-Durand, S; Lim, KC; Lustigman, S; Quirynen, L; Sakanari, J; Tekle, F, 2019) |
| "Flubendazole (FLBZ) is a potent and efficacious macrofilaricide after parenteral administration." | 1.48 | Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity. ( Burkman, E; Dzimianski, M; Geary, TG; Kengne-Ouafo, JA; Mackenzie, CD; Moorhead, A; Ndongmo, PC; Njouendou, JA; O'Neill, M; Wanji, S, 2018) |
| " Oral absorption is rapid compared with IM dosing; the absorption half-life (K01-HL) for the IM treatment is approximately 14 hr compared with 1 and 2 hr for the PO regimen of salt and free base forms, respectively." | 1.31 | Pharmacokinetics of UMF-078, a candidate antifilarial drug, in infected dogs. ( Dzimianski, MT; Fleckenstein, L; McCall, JW; Theplertboon, R, 2000) |
| "Mebendazole was given to infected animals for 2 weeks beginning 5 weeks (prepatent) or 16 weeks (patent) after infection." | 1.28 | Eosinophil hyporesponse of jirds induced by microfilariae of Brugia pahangi. ( Fujita, K; Horii, Y; Kurokawa, K; Mori, A; Nakanishi, H; Oda, T; Ueda, M; Zaitsu, M, 1989) |
| "Treatment with mebendazole (1." | 1.27 | Treatment of recurrent, filarial, Calabar-type oedema with mebendazole. ( Flocard, F; Van Hoegaerden, M, 1986) |
| "Patients harbouring Loa loa and/or Mansonella perstans infections, or presenting typical filarial symptomatology, were treated with mebendazole, a drug shown to be efficient in other parasitoses." | 1.27 | The use of mebendazole in the treatment of filariases due to Loa loa and Mansonella perstans. ( Chabaud, B; Flocard, F; Ivanoff, B; Salle, A; Van Hoegaerden, M, 1987) |
| "Flubendazole was macrofilaricidal at 5 x 2." | 1.26 | The anthelmintic effects of flubendazole on Brugia pahangi. ( Cho, SY; Denham, DA; Samad, R; Skippins, SC; Suswillo, RR, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (76.74) | 18.7374 |
| 1990's | 4 (9.30) | 18.2507 |
| 2000's | 2 (4.65) | 29.6817 |
| 2010's | 3 (6.98) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abuzar, S | 1 |
| Sharma, S | 2 |
| Fatma, N | 2 |
| Gupta, S | 1 |
| Murthy, PK | 1 |
| Katiyar, JC | 1 |
| Chatterjee, RK | 2 |
| Sen, AB | 1 |
| Stetter, N | 1 |
| Hartmann, W | 1 |
| Brunn, ML | 1 |
| Stanelle-Bertram, S | 1 |
| Gabriel, G | 1 |
| Breloer, M | 1 |
| O'Neill, M | 1 |
| Njouendou, JA | 1 |
| Dzimianski, M | 1 |
| Burkman, E | 1 |
| Ndongmo, PC | 1 |
| Kengne-Ouafo, JA | 1 |
| Wanji, S | 1 |
| Moorhead, A | 1 |
| Mackenzie, CD | 2 |
| Geary, TG | 1 |
| Fischer, C | 1 |
| Ibiricu Urriza, I | 1 |
| Bulman, CA | 1 |
| Lim, KC | 1 |
| Gut, J | 1 |
| Lachau-Durand, S | 2 |
| Engelen, M | 2 |
| Quirynen, L | 2 |
| Tekle, F | 2 |
| Baeten, B | 2 |
| Beerntsen, B | 1 |
| Lustigman, S | 1 |
| Sakanari, J | 1 |
| Hübner, MP | 1 |
| Ehrens, A | 1 |
| Koschel, M | 1 |
| Dubben, B | 1 |
| Lenz, F | 1 |
| Frohberger, SJ | 1 |
| Specht, S | 1 |
| Hoerauf, A | 1 |
| Saunders, M | 1 |
| Taubert, A | 1 |
| Dafa'alla, T | 1 |
| Zahner, H | 2 |
| Chand, P | 1 |
| Rai, RN | 1 |
| Dey, KP | 1 |
| Chakravertty, RK | 1 |
| Rao, CK | 2 |
| Mak, JW | 3 |
| Chan, WC | 1 |
| Sim, BK | 1 |
| Kwa, BH | 1 |
| Chusattayanond, W | 2 |
| Denham, DA | 6 |
| Almaviva, M | 1 |
| Galli, M | 1 |
| Rizzi, M | 1 |
| Simonelli, E | 1 |
| Negri, C | 1 |
| Vigevani, GM | 1 |
| Olumide, YM | 1 |
| Obembe, BM | 1 |
| Wahlgren, M | 2 |
| Frolov, I | 1 |
| Brandt, E | 1 |
| Van den Bossche, H | 1 |
| Horii, Y | 2 |
| Makimura, S | 1 |
| Ramanathan, S | 1 |
| Nair, NK | 1 |
| Mansor, SM | 1 |
| Navaratnam, V | 1 |
| Theplertboon, R | 1 |
| Fleckenstein, L | 1 |
| Dzimianski, MT | 1 |
| McCall, JW | 1 |
| Goldsmid, JM | 2 |
| Rogers, S | 2 |
| Narasimham, MV | 1 |
| Roychowdhury, SP | 1 |
| Das, M | 1 |
| Shibuya, T | 2 |
| Oikawa, Y | 1 |
| Saito, M | 1 |
| Tanaka, H | 2 |
| Samad, R | 1 |
| Cho, SY | 1 |
| Suswillo, RR | 2 |
| Skippins, SC | 1 |
| Bernberg, HC | 1 |
| Clarke, VV | 1 |
| Gelfand, M | 1 |
| Rogers, R | 1 |
| Karnad, DR | 1 |
| Meisheri, YV | 1 |
| Franz, M | 1 |
| Benten, P | 1 |
| Huseen, AM | 1 |
| Tanganelli, E | 1 |
| Nakanishi, H | 1 |
| Mori, A | 1 |
| Zaitsu, M | 1 |
| Ueda, M | 1 |
| Kurokawa, K | 1 |
| Oda, T | 1 |
| Fujita, K | 1 |
| Van Hoegaerden, M | 3 |
| Flocard, F | 3 |
| Sarma, RV | 1 |
| Vallishayee, RS | 1 |
| Rao, RS | 1 |
| Prabhakar, R | 1 |
| Tripathy, SP | 1 |
| Van Kerckhoven, I | 1 |
| Kumar, V | 1 |
| Burchard, GD | 1 |
| Kern, P | 1 |
| Maeda, R | 2 |
| Hayashi, Y | 2 |
| Nogami, S | 1 |
| Nakamura, M | 1 |
| Ivanoff, B | 1 |
| Salle, A | 1 |
| Chabaud, B | 1 |
| Richard-Lenoble, D | 1 |
| Kombila, M | 1 |
| Burnier, I | 1 |
| Maganga, ML | 1 |
3 trials available for mebendazole and Elaeophoriasis
| Article | Year |
|---|---|
Treatment of Brugia malayi infection with mebendazole and levamisole.
Topics: Adolescent; Adult; Aged; Benzimidazoles; Brugia; Clinical Trials as Topic; Drug Therapy, Combination | 1983 |
Levamisole and mebendazole in the treatment of bancroftian infection.
Topics: Benzimidazoles; Diethylcarbamazine; Filariasis; Humans; Levamisole; Mebendazole; Placebos; Wuchereri | 1978 |
Failure of high dose mebendazole as a microfilaricide in patients with loiasis.
Topics: Clinical Trials as Topic; Filariasis; Humans; Loiasis; Mebendazole | 1987 |
40 other studies available for mebendazole and Elaeophoriasis
| Article | Year |
|---|---|
Studies in potential filaricides. 18. Synthesis of 2,2'-disubstituted 5,5'-dibenzimidazolyl ketones and related compounds as potential anthelmintics.
Topics: Animals; Anthelmintics; Arvicolinae; Cestode Infections; Cricetinae; Drug Evaluation, Preclinical; F | 1986 |
A Combination of Deworming and Prime-Boost Vaccination Regimen Restores Efficacy of Vaccination Against Influenza in Helminth-Infected Mice.
Topics: Animals; Antinematodal Agents; Coinfection; Disease Models, Animal; Female; Filariasis; Filarioidea; | 2021 |
Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity.
Topics: Animals; Brugia malayi; Culicidae; Filariasis; Filaricides; Humans; Loa; Loiasis; Mebendazole; Micro | 2018 |
Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugia pahangi.
Topics: Administration, Oral; Animals; Brugia pahangi; Disease Models, Animal; Female; Filariasis; Filaricid | 2019 |
Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds.
Topics: Administration, Oral; Animals; Disease Models, Animal; Embryonic Development; Female; Filariasis; Fi | 2019 |
Effect of chemotherapeutic treatment on cytokine (IFN-gamma, IL-2, IL-4, IL-5, IL-10) gene transcription in response to specific antigens in Brugia malayi-infected Mastomys coucha.
Topics: Animals; Anthelmintics; Brugia malayi; Cytokines; Filariasis; Lymphocytes; Mebendazole; Murinae; Pep | 2008 |
Observations on mebendazole as a filaricide.
Topics: Adolescent; Adult; Benzimidazoles; Child; Female; Filariasis; Humans; Male; Mebendazole; Middle Aged | 1983 |
Effects of serum from treated patients on antibody-dependent cell adherence to the infective larvae of Brugia malayi.
Topics: Anthelmintics; Antibodies; Brugia; Cell Adhesion; Complement System Proteins; Diethylcarbamazine; Fi | 1983 |
Induction of host resistance to Brugia pahangi in jirds (Meriones unguiculatus) protected by chemoprophylaxis.
Topics: Animals; Antinematodal Agents; Benzimidazoles; Brugia; Female; Filariasis; Filarioidea; Gerbillinae; | 1984 |
Immune response in a symptomatic case of Tetrapetalonema perstans infection.
Topics: Antibody Formation; Cameroon; Diethylcarbamazine; Dipetalonema Infections; Female; Filariasis; Human | 1984 |
Dipetalonema perstans in a patient with chronic lymphoedema. Case report.
Topics: Adult; Dipetalonema Infections; Female; Filariasis; Humans; Levamisole; Lymphedema; Mebendazole | 1983 |
Treatment of Dipetalonema perstans infections with mebendazole.
Topics: Adult; Benzimidazoles; Child; Dipetalonema Infections; Female; Filariasis; Humans; Male; Mebendazole | 1983 |
Chemoprophylactic activity of flubendazole against Brugia pahangi in jirds.
Topics: Animals; Antinematodal Agents; Benzimidazoles; Brugia; Female; Filariasis; Filarioidea; Gerbillinae; | 1984 |
The successful treatment of Dipetalonema perstans filariasis with mebendazole.
Topics: Adult; Benzimidazoles; Diethylcarbamazine; Dipetalonema Infections; Female; Filariasis; Humans; Male | 1982 |
Anthelmintic properties of flubendazole against Dipetalonema viteae in jirds.
Topics: Animals; Antinematodal Agents; Benzimidazoles; Dipetalonema; Dipetalonema Infections; Filariasis; Ge | 1980 |
Chemoprophylactic activity of flubendazole against adult Brugia pahangi transplanted into the peritoneal cavity of jirds.
Topics: Animals; Anthelmintics; Benzimidazoles; Brugia; Female; Filariasis; Filaricides; Gerbillinae; Male; | 1980 |
A new look at the mode of action of some old and new antifilarial compounds.
Topics: Anthelmintics; Diethylcarbamazine; Filariasis; Filarioidea; Humans; Levamisole; Mebendazole; Suramin | 1981 |
Antifilarial activity of mebendazole and flubendazole on Breinlia booliati.
Topics: Animals; Antinematodal Agents; Benzimidazoles; Female; Filariasis; Filarioidea; Male; Mebendazole; R | 1981 |
Protective immunity against multiple challenges of Brugia pahangi in Mongolian gerbils induced by drug-abbreviated infection.
Topics: Animals; Brugia pahangi; Filariasis; Gerbillinae; Immunization; Larva; Male; Mebendazole; Rodent Dis | 1994 |
Determination of a new antifilarial drug, UMF-058, and mebendazole in whole blood by high-performance liquid chromatography.
Topics: Animals; Brugia malayi; Cercopithecidae; Chromatography, High Pressure Liquid; Filariasis; Filaricid | 1993 |
Pharmacokinetics of UMF-078, a candidate antifilarial drug, in infected dogs.
Topics: Administration, Oral; Animals; Antinematodal Agents; Area Under Curve; Biological Availability; Brug | 2000 |
Studies on the diagnosis and treatment of human filariasis in Rhodesia.
Topics: Adult; Aged; Blood; Dipetalonema; Dipetalonema Infections; Filariasis; Humans; Male; Mebendazole; St | 1976 |
Mebendazole--a slow acting macro- and microfilaricide against Litomosoides carinii in cotton rat.
Topics: Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Female; Filariasis; Filaricides; Filar | 1979 |
The anthelmintic effects of flubendazole on Brugia pahangi.
Topics: Animals; Anthelmintics; Benzimidazoles; Brugia; Cats; Drug Administration Schedule; Female; Filarias | 1979 |
A preliminary study on the treatment of filariasis due to dipetalonema perstans.
Topics: Adult; Aged; Dipetalonema Infections; Filariasis; Humans; Levamisole; Male; Mebendazole | 1979 |
The combined treatment with levamisole and mebendazole for a perstans-like filarial infection in Rhodesia.
Topics: Adult; Benzimidazoles; Dipetalonema Infections; Drug Therapy, Combination; Female; Filariasis; Human | 1979 |
Studies with Brugia pahangi 19. Anthelmintic effects of mebendazole.
Topics: Animals; Benzimidazoles; Brugia; Cats; Female; Filariasis; Male; Mebendazole | 1978 |
Mebendazole with levamisole in tropical pulmonary eosinophilia: an alternative in diethylcarbamazine allergy.
Topics: Animals; Diethylcarbamazine; Drug Hypersensitivity; Drug Therapy, Combination; Filariasis; Humans; L | 1992 |
Fine-structure alterations in female Brugia malayi and Litomosoides carinii after in vivo treatment with flubendazole.
Topics: Animals; Antinematodal Agents; Brugia; Elephantiasis, Filarial; Female; Filariasis; Filarioidea; Meb | 1990 |
2,2'-Dicarbomethoxyamino-5,5'-dibenzimidazolyl ketone--a new antifilarial agent.
Topics: Administration, Oral; Animals; Anthelmintics; Arvicolinae; Benzimidazoles; Diethylcarbamazine; Dose- | 1989 |
[Elephantiasis of the vulva and the legs. Medical and surgical treatment of a case of lymphatic filariasis].
Topics: Adult; Combined Modality Therapy; Elephantiasis, Filarial; Female; Filariasis; Humans; Leg; Mebendaz | 1989 |
Eosinophil hyporesponse of jirds induced by microfilariae of Brugia pahangi.
Topics: Animals; Brugia; Chronic Disease; Eosinophils; Filariasis; Gerbillinae; Male; Mebendazole; Microfila | 1989 |
Mebendazole treatment of loaiasis.
Topics: Benzimidazoles; Diethylcarbamazine; Filariasis; Humans; Loiasis; Mebendazole | 1985 |
Use of mebendazole in combination with DEC in bancroftian filariasis.
Topics: Adolescent; Adult; Animals; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Filarial; | 1988 |
Macrofilaricidal activity of oral flubendazole on Brugia pahangi.
Topics: Administration, Oral; Animals; Antinematodal Agents; Brugia; Female; Filariasis; Heart; Lung; Male; | 1988 |
Basic studies on the laboratory assessment of macrofilaricides using Brugia malayi in the jird, Meriones unguiculatus. 2. Establishment and evaluation of a new method of macrofilaricide assessment.
Topics: Animals; Anthelmintics; Arsenicals; Brugia; Diethylcarbamazine; Drug Evaluation, Preclinical; Elepha | 1988 |
Effect of milbemycin D on Dipetalonema viteae in the hamster and in vitro.
Topics: Animals; Anti-Bacterial Agents; Cricetinae; Dipetalonema; Dipetalonema Infections; Female; Filariasi | 1987 |
Treatment of recurrent, filarial, Calabar-type oedema with mebendazole.
Topics: Adult; Dipetalonema Infections; Edema; Filariasis; Gabon; Humans; Loa; Loiasis; Male; Mebendazole; R | 1986 |
The use of mebendazole in the treatment of filariases due to Loa loa and Mansonella perstans.
Topics: Adolescent; Adult; Animals; Filariasis; Humans; Loiasis; Mansonelliasis; Mebendazole; Microfilariae; | 1987 |
[Filariasis in Gabon: treatment with mebendazole of filariasis due to M. perstans and Loa loa].
Topics: Filariasis; Gabon; Humans; Loiasis; Mansonelliasis; Mebendazole | 1985 |