mebendazole has been researched along with Carcinoma, Ovarian Epithelial in 1 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Carcinoma, Ovarian Epithelial: A malignant neoplasm that originates in cells on the surface EPITHELIUM of the ovary and is the most common form of ovarian cancer. There are five histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Mutations in BRCA1, OPCML, PRKN, PIK3CA, AKT1, CTNNB1, RRAS2, and CDH1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ovarian cancer is the third most common cancer and the second most common cause of gynecologic cancer death in women." | 1.62 | Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. ( Chen, C; Haydon, RC; He, F; He, TC; Huang, L; Liu, Q; Luu, HH; Ni, N; Reid, RR; Shen, L; Shi, D; Tang, L; Wagstaff, W; Wang, H; Zhang, J; Zhao, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L | 1 |
| Zhao, L | 1 |
| Zhang, J | 1 |
| He, F | 1 |
| Wang, H | 1 |
| Liu, Q | 1 |
| Shi, D | 1 |
| Ni, N | 1 |
| Wagstaff, W | 1 |
| Chen, C | 1 |
| Reid, RR | 1 |
| Haydon, RC | 1 |
| Luu, HH | 1 |
| Shen, L | 1 |
| He, TC | 1 |
| Tang, L | 1 |
1 other study available for mebendazole and Carcinoma, Ovarian Epithelial
| Article | Year |
|---|---|
Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways.
Topics: Animals; Antinematodal Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Ovarian Epithelial; Cell | 2021 |