mebendazole has been researched along with Benign Cerebellar Neoplasms in 3 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mebendazole (MBZ) has a long safety record as antiparasitic in children and has been recently implicated in inhibition of various tyrosine kinases in vitro." | 5.42 | Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis. ( Bai, RY; Bunz, F; Riggins, GJ; Rudin, CM; Staedtke, V, 2015) |
| "Mebendazole (MBZ) has a long safety record as antiparasitic in children and has been recently implicated in inhibition of various tyrosine kinases in vitro." | 1.42 | Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis. ( Bai, RY; Bunz, F; Riggins, GJ; Rudin, CM; Staedtke, V, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, J | 1 |
| Hadden, MK | 1 |
| Bai, RY | 1 |
| Staedtke, V | 1 |
| Rudin, CM | 1 |
| Bunz, F | 1 |
| Riggins, GJ | 1 |
| Bodhinayake, I | 1 |
| Symons, M | 1 |
| Boockvar, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors[NCT02644291] | Phase 1 | 16 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mebendazole and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
Medulloblastoma drugs in development: Current leads, trials and drawbacks.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cerebellar Neoplasms; Humans; Medulloblastoma; Pro | 2021 |
2 other studies available for mebendazole and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cerebellar Neoplasms; Female; Humans; Mebendazole; | 2015 |
Repurposing mebendazole for the treatment of medulloblastoma.
Topics: Animals; Anthelmintics; Antineoplastic Agents; Cerebellar Neoplasms; Humans; Mebendazole; Medullobla | 2015 |