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mebendazole and Bancroftian Elephantiasis

mebendazole has been researched along with Bancroftian Elephantiasis in 12 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Flubendazole (FBZ) was approved in 1980 for the treatment of gastrointestinal nematode infections in both veterinary and human medicine."2.61Flubendazole as a macrofilaricide: History and background. ( Geary, TG; Mackenzie, CD; Silber, SA, 2019)
"loa L3 and treated with 10 mg/kg FLBZ once daily for 5 consecutive days."1.51Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents. ( Chunda, VC; Enyong, P; Fombad, FF; Gandjui, NVT; Hoerauf, A; Mackenzie, CD; Metuge, HM; Ndongmo, PC; Njiokou, F; Njouendou, AJ; Ritter, M; Wanji, S, 2019)
"Mebendazole (MBZ) treatment at the early prepatent (5-7 weeks of post infection) or the late prepatent (7-9 weeks of post infection) period was highly effective in causing almost complete eradication of the primary infection."1.28Induction of protective immunity to Brugia pahangi in jirds by drug-abbreviated infection. ( Fujita, K; Horii, Y; Kurokawa, K; Mori, A; Nakanishi, H; Oda, T; Ueda, M; Zaitsu, M, 1992)
"The chemotherapeutic efficacy of mebendazole given in combination with Freund's complete adjuvant (FCA) against Brugia malayi in multimammate rat was evaluated."1.28Brugia malayi in Mastomys natalensis: efficacy of mebendazole in combination with Freund's complete adjuvant. ( Chatterjee, RK; Murthy, PK; Tyagi, K, 1992)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fombad, FF1
Njouendou, AJ1
Ndongmo, PC1
Ritter, M1
Chunda, VC1
Metuge, HM1
Gandjui, NVT1
Enyong, P1
Njiokou, F1
Hoerauf, A1
Mackenzie, CD3
Wanji, S1
Geary, TG2
Silber, SA1
Figueredo-Silva, J1
Dreyer, G1
GuimarĂ£es, K1
Brandt, C1
Medeiros, Z1
Horii, Y1
Nakanishi, H1
Mori, A1
Ueda, M1
Kurokawa, K1
Zaitsu, M1
Oda, T1
Fujita, K1
Murthy, PK1
Tyagi, K1
Chatterjee, RK1
Franz, M1
Zahner, H1
Benten, P1
Huseen, AM1
Tanganelli, E1
Sarma, RV1
Vallishayee, RS1
Rao, RS1
Prabhakar, R1
Tripathy, SP1
Maeda, R1
Hayashi, Y1
Shibuya, T1
Kumar, V2
Ghenim, H1
Brandt, J1
Vanparijs, O2
de Burbure, G1

Reviews

1 review available for mebendazole and Bancroftian Elephantiasis

ArticleYear
Flubendazole as a macrofilaricide: History and background.
    PLoS neglected tropical diseases, 2019, Volume: 13, Issue:1

    Topics: Albendazole; Animals; Diethylcarbamazine; Elephantiasis, Filarial; Filaricides; Gastrointestinal Dis

2019

Other Studies

11 other studies available for mebendazole and Bancroftian Elephantiasis

ArticleYear
Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents.
    Parasites & vectors, 2019, Jan-08, Volume: 12, Issue:1

    Topics: Africa, Central; Africa, Western; Animals; Cell Line; Elephantiasis, Filarial; Filaricides; Hydrolys

2019
Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs.
    Expert review of anti-infective therapy, 2011, Volume: 9, Issue:5

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anthelmintics; beta-Cyclodextrins; Brugia; Chemistry, Ph

2011
Bancroftian lymphadenopathy: absence of eosinophils in tissues despite peripheral blood hypereosinophilia.
    The Journal of tropical medicine and hygiene, 1994, Volume: 97, Issue:1

    Topics: Adolescent; Animals; Child; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Filarial;

1994
Induction of protective immunity to Brugia pahangi in jirds by drug-abbreviated infection.
    Journal of helminthology, 1992, Volume: 66, Issue:2

    Topics: Animals; Brugia; Elephantiasis, Filarial; Eosinophilia; Gerbillinae; Male; Mebendazole

1992
Brugia malayi in Mastomys natalensis: efficacy of mebendazole in combination with Freund's complete adjuvant.
    Folia parasitologica, 1992, Volume: 39, Issue:1

    Topics: Administration, Oral; Animals; Antibodies, Helminth; Brugia; Elephantiasis, Filarial; Freund's Adjuv

1992
Fine-structure alterations in female Brugia malayi and Litomosoides carinii after in vivo treatment with flubendazole.
    Parasitology research, 1990, Volume: 76, Issue:5

    Topics: Animals; Antinematodal Agents; Brugia; Elephantiasis, Filarial; Female; Filariasis; Filarioidea; Meb

1990
[Elephantiasis of the vulva and the legs. Medical and surgical treatment of a case of lymphatic filariasis].
    Minerva ginecologica, 1989, Volume: 41, Issue:11

    Topics: Adult; Combined Modality Therapy; Elephantiasis, Filarial; Female; Filariasis; Humans; Leg; Mebendaz

1989
Use of mebendazole in combination with DEC in bancroftian filariasis.
    The Indian journal of medical research, 1988, Volume: 87

    Topics: Adolescent; Adult; Animals; Diethylcarbamazine; Drug Therapy, Combination; Elephantiasis, Filarial;

1988
Basic studies on the laboratory assessment of macrofilaricides using Brugia malayi in the jird, Meriones unguiculatus. 2. Establishment and evaluation of a new method of macrofilaricide assessment.
    The Japanese journal of experimental medicine, 1988, Volume: 58, Issue:1

    Topics: Animals; Anthelmintics; Arsenicals; Brugia; Diethylcarbamazine; Drug Evaluation, Preclinical; Elepha

1988
Flubendazole in-feed preparation for prophylaxis of experimental lymphatic filariasis.
    Annales de la Societe belge de medecine tropicale, 1987, Volume: 67, Issue:1

    Topics: Animals; Anthelmintics; Brugia; Elephantiasis, Filarial; Filaricides; Lymphedema; Male; Mebendazole;

1987
Prophylactic activity of flubendazole-medicated feed on Brugia pahangi infection of multimammate rats.
    Annals of tropical medicine and parasitology, 1986, Volume: 80, Issue:4

    Topics: Administration, Oral; Animals; Antinematodal Agents; Brugia; Elephantiasis, Filarial; Food; Lymphede

1986