mebendazole has been researched along with Aneuploid in 3 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " But since it is obvious from dose-response curves where the inflection point/threshold lies, it appears that the model might be picking up some irregularities (possibly due to experimental variability in the dose-response curve at concentrations greater than the threshold)." | 1.30 | Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes. ( Elhajouji, A; Kirsch-Volders, M; Tibaldi, F, 1997) |
| " MBC and MEB are poorly soluble in water and therefore have a low bioavailability in vivo." | 1.29 | Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes. ( Elhajouji, A; Kirsch-Volders, M; Van Hummelen, P, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Hummelen, P | 2 |
| Elhajouji, A | 3 |
| Kirsch-Volders, M | 3 |
| Tibaldi, F | 1 |
3 other studies available for mebendazole and Aneuploid
| Article | Year |
|---|---|
Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes.
Topics: Adult; Aneuploidy; Animals; Benzimidazoles; Biotransformation; Carbamates; Cells, Cultured; Chromoso | 1995 |
Indications for a threshold of chemically-induced aneuploidy in vitro in human lymphocytes.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cell Division; Cell Survival; Cells, Cultured; Centro | 1995 |
Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Human; Chromosomes, Human, Pair 1; Chrom | 1997 |