Page last updated: 2024-10-30

mebendazole and Anemia

mebendazole has been researched along with Anemia in 21 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
"To assess the following associations between the second and third trimesters of pregnancy: (i) the intensity of soil-transmitted helminth (STH) infection and haemoglobin/anaemia, (ii) the effect of mebendazole treatment on the occurrence of STH infection, and (iii) the effect of mebendazole treatment on haemoglobin/anaemia."5.15Trichuris and hookworm infections associated with anaemia during pregnancy. ( Casapía, M; Gilbert, NL; Gyorkos, TW; Larocque, R, 2011)
"We assessed the effectiveness of iron+folic acid for the treatment of severe anemia [hemoglobin (Hb) <70 g/L] and the efficacy of added multivitamins and/or anthelminthics among children aged 6-24 mo in periurban Karachi, Pakistan."5.14Treatment response to iron and folic acid alone is the same as with multivitamins and/or anthelminthics in severely anemic 6- to 24-month-old children. ( Bhutta, Z; Christian, P; Klemm, R; Rah, JH; Rizvi, A; Shahid, F, 2009)
"The authors report a case of massive Trichuris trichiura infection, resulting in severe anaemia and congestive cardiac failure in a 9-year-old Iban boy, who was resistant to the usual oral anthelmintic treatment, but promptly responded to mebendazole retention enema."3.67Mebendazole retention enema for severe Trichuris trichiura (whipworm) infection: a case report. ( Bhattacharya, S; Ray, S; Sebastian, VJ, 1989)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's3 (14.29)18.2507
2000's7 (33.33)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCormack, T1
Ayub, R1
Aziz, F1
Motta, L1
Spaeth, B1
Shephard, M1
Staudacher, O1
Heimer, J1
Steiner, F1
Kayonga, Y1
Havugimana, JM1
Ignatius, R1
Musemakweri, A1
Ngabo, F1
Harms, G1
Gahutu, JB1
Mockenhaupt, FP1
Loukas, A1
Hotez, PJ1
Diemert, D1
Yazdanbakhsh, M1
McCarthy, JS1
Correa-Oliveira, R1
Croese, J1
Bethony, JM1
Tariq, M1
Muzammil, SM1
Shaikh, FA1
Pal, KM1
Henao-Martínez, AF1
Madinger, N1
Christian, P2
Shahid, F2
Rizvi, A2
Klemm, RD1
Bhutta, ZA1
Bhutta, Z1
Klemm, R1
Rah, JH1
Smith, JL1
Brooker, S1
Gyorkos, TW2
Gilbert, NL1
Larocque, R2
Casapía, M2
Watthanakulpanich, D1
Maipanich, W1
Pubampen, S1
Sa-Nguankiat, S1
Pooudouang, S1
Chantaranipapong, Y1
Homsuwan, N1
Nawa, Y1
Waikagul, J1
Albonico, M1
Ramsan, M1
Wright, V1
Jape, K1
Haji, HJ1
Taylor, M1
Savioli, L1
Bickle, Q1
Khieu, V1
Odermatt, P1
Mel, Y1
Keluangkhot, V1
Strobel, M1
Gotuzzo, E1
MacLean, JD1
Soto, JC1
Rahme, E1
Ulukanligil, M1
Le Huong, T1
Brouwer, ID1
Nguyen, KC1
Burema, J1
Kok, FJ1
Holzer, BR1
Egger, M1
Teuscher, T1
Koch, S1
Mboya, DM1
Smith, GD1
Gove, S1
Islam, N1
Padelt, H1
Hölzer, E1
Romani, Sde A1
de Lira, PI1
Batista Filho, M1
Sequeira, LA1
de Freitas, CL1
Sebastian, VJ1
Bhattacharya, S1
Ray, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Anthelminthics and Multivitamins for Treatment of Severe Anemia in Pregnant Women and Children 6-24 Months of Age in Pakistan[NCT00116493]Phase 31,009 participants (Actual)Interventional2004-04-30Completed
A Study to Evaluate the Effectiveness of e-IMCI Implementation Compared to Standard of Care for Sick Children Aged Under Five Years in Primary Health Care Clinics in KwaZulu-Natal, South Africa.[NCT04074083]291 participants (Actual)Interventional2021-01-22Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for mebendazole and Anemia

ArticleYear
Hookworm infection.
    Nature reviews. Disease primers, 2016, 12-08, Volume: 2

    Topics: Albendazole; Ancylostomatoidea; Anemia; Animals; Anthelmintics; Factor VIIa; Factor Xa; Factor XIa;

2016
Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review.
    Tropical medicine & international health : TM & IH, 2010, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Aged; Albendazole; Anemia; Anthelmintics; Child; Child, Preschool; Female; Hemogl

2010

Trials

6 trials available for mebendazole and Anemia

ArticleYear
Treatment response to standard of care for severe anemia in pregnant women and effect of multivitamins and enhanced anthelminthics.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:3

    Topics: Adult; Anemia; Antinematodal Agents; Female; Folic Acid; Hemoglobins; Humans; Iron; Iron Deficiencie

2009
Treatment response to iron and folic acid alone is the same as with multivitamins and/or anthelminthics in severely anemic 6- to 24-month-old children.
    The Journal of nutrition, 2009, Volume: 139, Issue:8

    Topics: Anemia; Anemia, Iron-Deficiency; Antinematodal Agents; Child, Preschool; Double-Blind Method; Drug T

2009
Trichuris and hookworm infections associated with anaemia during pregnancy.
    Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Anemia; Animals; Antinematodal Agents; Ascariasis; Ascaris lumbricoides; Female;

2011
A double-blind randomized controlled trial of antenatal mebendazole to reduce low birthweight in a hookworm-endemic area of Peru.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:10

    Topics: Adult; Anemia; Antinematodal Agents; Double-Blind Method; Endemic Diseases; Female; Hookworm Infecti

2006
The effect of iron fortification and de-worming on anaemia and iron status of Vietnamese schoolchildren.
    The British journal of nutrition, 2007, Volume: 97, Issue:5

    Topics: Anemia; Antinematodal Agents; Ascariasis; C-Reactive Protein; Child; Female; Food, Fortified; Hemogl

2007
Childhood anemia in Africa: to transfuse or not transfuse?
    Acta tropica, 1993, Volume: 55, Issue:1-2

    Topics: Anemia; Blood Transfusion; Child, Preschool; Chloroquine; Hematocrit; HIV Infections; Hookworm Infec

1993

Other Studies

13 other studies available for mebendazole and Anemia

ArticleYear
Point-of-care testing facilitates screening and treatment for anaemia in women and children in rural Pakistan.
    The Australian journal of rural health, 2018, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Anemia; Child; Female; Hemoglobins; Humans; Iron; Male; Mass Screening; Mebendazo

2018
Soil-transmitted helminths in southern highland Rwanda: associated factors and effectiveness of school-based preventive chemotherapy.
    Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:7

    Topics: Anemia; Animals; Anthelmintics; Anthropometry; Ascariasis; Ascaris lumbricoides; Child; Child, Presc

2014
Hookworm infestation as a cause of melena and severe anaemia in farmer.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:2

    Topics: Anemia; Antinematodal Agents; Duodenum; Farmers; Hookworm Infections; Humans; Male; Mebendazole; Mel

2017
Anemia During Pregnancy-The Enemies Within.
    The American journal of the medical sciences, 2017, Volume: 353, Issue:3

    Topics: Administration, Oral; Adult; Albendazole; Anemia; Animals; Female; Hematocrit; Hemoglobins; Humans;

2017
Impact of hookworm deworming on anemia and nutritional status among children in Thailand.
    The Southeast Asian journal of tropical medicine and public health, 2011, Volume: 42, Issue:4

    Topics: Adolescent; Albendazole; Anemia; Anthelmintics; Child; Child, Preschool; Endemic Diseases; Female; H

2011
Soil-transmitted nematode infections and mebendazole treatment in Mafia Island schoolchildren.
    Annals of tropical medicine and parasitology, 2002, Volume: 96, Issue:7

    Topics: Adolescent; Anemia; Animals; Antinematodal Agents; Ascaris lumbricoides; Child; Cross-Sectional Stud

2002
[Anaemia in a school of rural Cambodia: detection, prevalence, and links with intestinal worms and malnutrition].
    Bulletin de la Societe de pathologie exotique (1990), 2006, Volume: 99, Issue:2

    Topics: Ancylostomiasis; Anemia; Antinematodal Agents; Cambodia; Child; False Positive Reactions; Female; He

2006
[The results of a control program carried out on school children for intestinal parasites in Sanliurfa province, Turkey between the years of 2001 and 2005].
    Turkiye parazitolojii dergisi, 2006, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Anemia; Antinematodal Agents; Child; Child Nutrition Disorders; Child, Preschool;

2006
Integrated management of childhood illness by outpatient health workers: technical basis and overview. The WHO Working Group on Guidelines for Integrated Management of the Sick Child.
    Bulletin of the World Health Organization, 1997, Volume: 75 Suppl 1

    Topics: Ambulatory Care; Ambulatory Care Facilities; Anemia; Antinematodal Agents; Child; Child Nutrition Di

1997
Helminthiasis and anaemia in rural Bangladesh.
    Tropical doctor, 1979, Volume: 9, Issue:4

    Topics: Adult; Anemia; Bangladesh; Child; Ferrous Compounds; Helminthiasis; Humans; Mebendazole; Thiabendazo

1979
["Imported" infectious diseases--selected helminthiases].
    Zeitschrift fur arztliche Fortbildung, 1979, Jul-15, Volume: 73, Issue:13-14

    Topics: Adolescent; Anemia; Animals; Cestode Infections; Disease Vectors; Female; Helminthiasis; Humans; Meb

1979
[Anemias in preschool children: diagnosis, treatment and evaluation, Recife-PE, Brazil].
    Archivos latinoamericanos de nutricion, 1991, Volume: 41, Issue:2

    Topics: Anemia; Anemia, Hypochromic; Brazil; Child; Child, Preschool; Follow-Up Studies; Hemoglobins; Humans

1991
Mebendazole retention enema for severe Trichuris trichiura (whipworm) infection: a case report.
    The Journal of tropical medicine and hygiene, 1989, Volume: 92, Issue:1

    Topics: Anemia; Brunei; Child; Enema; Entamoebiasis; Heart Failure; Humans; Male; Mebendazole; Metronidazole

1989