mebendazole has been researched along with Agranulocytosis in 4 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two patients receiving oral high-dose mebendazole therapy for echinococcosis were found to have severe, reversible neutropenia, apparently due to marrow suppression; platelets and RBCs were also reversibly suppressed in one." | 7.66 | Severe, reversible neutropenia during high-dose mebendazole therapy for echinococcosis. ( Axelrod, JL; Levin, MH; Schantz, PM; Weinstein, RA, 1983) |
| " We present a case report of a patient with alveolar hydatid disease, whose treatment with mebendazole was brief due to side effects of alopecia and granulocytopenia; and review the features of this disease which, with increasing international migration, may be encountered more frequently in Australia." | 3.67 | Hydatid disease: the alveolar variety in Australia. A case report with comment on the toxicity of mebendazole. ( Braithwaite, PA; Thomas, RJ; Thompson, RC, 1985) |
| "Two patients receiving oral high-dose mebendazole therapy for echinococcosis were found to have severe, reversible neutropenia, apparently due to marrow suppression; platelets and RBCs were also reversibly suppressed in one." | 3.66 | Severe, reversible neutropenia during high-dose mebendazole therapy for echinococcosis. ( Axelrod, JL; Levin, MH; Schantz, PM; Weinstein, RA, 1983) |
| "Five red-legged pademelons (Thylogale stigmatica) were dosed orally with mebendazole at 50 mg/kg/d for 5 to 6 days." | 1.32 | Toxic effects of mebendazole at high dose on the haematology of red-legged pademelons (Thylogale stigmatica). ( Berger, L; Johnson, PM; Skerratt, LF; Speare, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Speare, R | 1 |
| Skerratt, LF | 1 |
| Berger, L | 1 |
| Johnson, PM | 1 |
| Levin, MH | 1 |
| Weinstein, RA | 1 |
| Axelrod, JL | 1 |
| Schantz, PM | 1 |
| Braithwaite, PA | 1 |
| Thomas, RJ | 1 |
| Thompson, RC | 1 |
| Fernández-Bañares, F | 1 |
| González-Huix, F | 1 |
| Xiol, X | 1 |
| Catalá, I | 1 |
| Miró, J | 1 |
| López, N | 1 |
| Casais, L | 1 |
4 other studies available for mebendazole and Agranulocytosis
| Article | Year |
|---|---|
Toxic effects of mebendazole at high dose on the haematology of red-legged pademelons (Thylogale stigmatica).
Topics: Agranulocytosis; Animals; Antinematodal Agents; Leukocyte Count; Marsupialia; Mebendazole | 2004 |
Severe, reversible neutropenia during high-dose mebendazole therapy for echinococcosis.
Topics: Aged; Agranulocytosis; Benzimidazoles; Bone Marrow; Echinococcosis, Hepatic; Echinococcosis, Pulmona | 1983 |
Hydatid disease: the alveolar variety in Australia. A case report with comment on the toxicity of mebendazole.
Topics: Agranulocytosis; Alopecia; Australia; Echinococcosis, Hepatic; Female; Humans; Japan; Liver; Mebenda | 1985 |
Marrow aplasia during high dose mebendazole treatment.
Topics: Aged; Agranulocytosis; Bone Marrow; Echinococcosis, Hepatic; Humans; Leukocyte Count; Male; Mebendaz | 1986 |