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mebendazole and Abnormalities, Drug-Induced

mebendazole has been researched along with Abnormalities, Drug-Induced in 10 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"The Israeli Teratogen Information Service prospectively collected and followed 192 pregnancies exposed to mebendazole in pregnancy, 71."7.72Pregnancy outcome after gestational exposure to mebendazole: a prospective controlled cohort study. ( Arnon, J; Diav-Citrin, O; Lubart, I; Ornoy, A; Shechtman, S, 2003)
"In areas endemic for hookworm, routine antenatal mebendazole therapy could greatly reduce the prevalence of anaemia in pregnancy."7.70Effect of mebendazole therapy during pregnancy on birth outcome. ( de Silva, HJ; de Silva, NR; Gunasekera, DP; Ismail, MM; Sirisena, JL, 1999)
"The objectives of the study was to check the embryotoxic-teratogenic and fetotoxic effect of mebendazole (Vermox; Richter, Budapest, Hungary) treatment during pregnancy."3.73Population-based case-control study of mebendazole in pregnant women for birth outcomes. ( Acs, N; Bánhidy, F; Czeizel, AE; Puhó, E, 2005)
" An enhancing role of pregnancy, which may be suspected in this case, the favourable outcome after surgery and chemotherapy, and also a mental disability in a child following long-term intrauterine exposure to mebendazole, make the report particularly unique."3.73Brain metastasis of alveolar echinococcosis in a hyperendemic focus of Echinococcus multilocularis infection. ( Craig, PS; Jones, MK; McManus, DP; Vuitton, DA; Yang, YR, 2005)
"The Israeli Teratogen Information Service prospectively collected and followed 192 pregnancies exposed to mebendazole in pregnancy, 71."3.72Pregnancy outcome after gestational exposure to mebendazole: a prospective controlled cohort study. ( Arnon, J; Diav-Citrin, O; Lubart, I; Ornoy, A; Shechtman, S, 2003)
"In areas endemic for hookworm, routine antenatal mebendazole therapy could greatly reduce the prevalence of anaemia in pregnancy."3.70Effect of mebendazole therapy during pregnancy on birth outcome. ( de Silva, HJ; de Silva, NR; Gunasekera, DP; Ismail, MM; Sirisena, JL, 1999)
"Flubendazole, the p-fluoroderivative of mebendazole, was suspended in deionized water, and administered by gavage once daily to pregnant rats on days 8 through 15 of pregnancy at 0 (control), 2."3.67Teratogenicity of flubendazole in rats. ( Yoshimura, H, 1987)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's1 (10.00)18.2507
2000's4 (40.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Torp-Pedersen, A1
Jimenez-Solem, E1
Cejvanovic, V1
Poulsen, HE1
Andersen, JT1
Longo, M1
Zanoncelli, S1
Colombo, PA1
Harhay, MO1
Scandale, I1
Mackenzie, C1
Geary, T1
Madrill, N1
Mazué, G1
Savioli, L1
Crompton, DW1
Neira, M1
Diav-Citrin, O1
Shechtman, S1
Arnon, J1
Lubart, I1
Ornoy, A1
Acs, N1
Bánhidy, F1
Puhó, E1
Czeizel, AE1
Yang, YR1
Vuitton, DA1
Jones, MK1
Craig, PS1
McManus, DP1
de Silva, NR1
Sirisena, JL1
Gunasekera, DP1
Ismail, MM1
de Silva, HJ1
Delatour, P1
Lorgue, G1
Lapras, M1
Richard, Y1
Baskerville, M1
Wood, M1
Newton, CM1
Yoshimura, H1

Other Studies

10 other studies available for mebendazole and Abnormalities, Drug-Induced

ArticleYear
Birth outcomes after exposure to mebendazole and pyrvinium during pregnancy - A Danish nationwide cohort study.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2016, Volume: 36, Issue:8

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anthelmintics; Cohort Studies; Denmark; Female; Helm

2016
Effects of the benzimidazole anthelmintic drug flubendazole on rat embryos in vitro.
    Reproductive toxicology (Elmsford, N.Y.), 2013, Volume: 36

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anthelmintics; Biotransformation; Cel

2013
Use of anthelminthic drugs during pregnancy.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:1

    Topics: Abnormalities, Drug-Induced; Anthelmintics; Female; Humans; Maternal-Fetal Exchange; Mebendazole; Pr

2003
Pregnancy outcome after gestational exposure to mebendazole: a prospective controlled cohort study.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:1

    Topics: Abnormalities, Drug-Induced; Abortion, Induced; Adult; Antinematodal Agents; Birth Weight; Cohort St

2003
Population-based case-control study of mebendazole in pregnant women for birth outcomes.
    Congenital anomalies, 2005, Volume: 45, Issue:3

    Topics: Abnormalities, Drug-Induced; Birth Weight; Case-Control Studies; Female; Gestational Age; Humans; In

2005
Brain metastasis of alveolar echinococcosis in a hyperendemic focus of Echinococcus multilocularis infection.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:12

    Topics: Abnormalities, Drug-Induced; Anthelmintics; Brain Diseases; Central Nervous System Protozoal Infecti

2005
Effect of mebendazole therapy during pregnancy on birth outcome.
    Lancet (London, England), 1999, Apr-03, Volume: 353, Issue:9159

    Topics: Abnormalities, Drug-Induced; Antinematodal Agents; Cross-Sectional Studies; Endemic Diseases; Female

1999
[Embryotoxic and antimitotic properties of parbendazole, mebendazole and cambendazole].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1976, Feb-02, Volume: 282, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Benzimidazoles; Cambendazole; Carcinoma, Ehrlich Tumor; Embryo

1976
Mebendazole for worming mice: effectiveness and side effects.
    Laboratory animals, 1988, Volume: 22, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Female; Hymenolepiasis; Male; Mebendazole; Mice; Nematode Infe

1988
Teratogenicity of flubendazole in rats.
    Toxicology, 1987, Volume: 43, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Female; Fetal Resorption; Litter Size

1987