mdl-100907 and Hepatitis-C

mdl-100907 has been researched along with Hepatitis-C* in 1 studies

Other Studies

1 other study(ies) available for mdl-100907 and Hepatitis-C

Article	Year
Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy. Protein & cell, 2019, Volume: 10, Issue:3 Hepatitis C virus (HCV) is a leading cause of liver disease worldwide. Although several HCV protease/polymerase inhibitors were recently approved by U.S. FDA, the combination of antivirals targeting multiple processes of HCV lifecycle would optimize anti-HCV therapy and against potential drug-resistance. Viral entry is an essential target step for antiviral development, but FDA-approved HCV entry inhibitor remains exclusive. Here we identify serotonin 2A receptor (5-HT Topics: Animals; Antiviral Agents; Claudin-1; HEK293 Cells; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Mice; Phenoxybenzamine; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Virus Internalization	2019

Article

Year

Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy.

Protein & cell, 2019, Volume: 10, Issue:3

Hepatitis C virus (HCV) is a leading cause of liver disease worldwide. Although several HCV protease/polymerase inhibitors were recently approved by U.S. FDA, the combination of antivirals targeting multiple processes of HCV lifecycle would optimize anti-HCV therapy and against potential drug-resistance. Viral entry is an essential target step for antiviral development, but FDA-approved HCV entry inhibitor remains exclusive. Here we identify serotonin 2A receptor (5-HT

Topics: Animals; Antiviral Agents; Claudin-1; HEK293 Cells; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Mice; Phenoxybenzamine; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Virus Internalization

2019