mci 9038 has been researched along with Venous Thrombosis in 53 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (5.66) | 18.2507 |
2000's | 22 (41.51) | 29.6817 |
2010's | 25 (47.17) | 24.3611 |
2020's | 3 (5.66) | 2.80 |
Authors | Studies |
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Chung, KH; Jung, WH; Kang, M; Kim, A; Kim, EE; Kwon, OH; Lee, K; Lee, SH; Lee, SK; Park, CW; Park, DH; Park, HD; Park, SK; Yoon, SK | 1 |
Almond, HR; Andrade-Gordon, P; Corcoran, TW; Costanzo, MJ; de Garavilla, L; Giardino, EC; Haertlein, BJ; Hecker, LR; Kauffman, JA; Lewis, JM; Maryanoff, BE; Schott, MR; Yabut, SC; Zhang, HC | 1 |
Andrade-Gordon, P; Ballentine, SK; Bone, RF; Brown, K; Crysler, CS; Damiano, BP; End, D; Giardino, EC; Lu, T; Markotan, T; Maryanoff, BE; Player, MR; Shukla, U; Spurlino, J; Tomczuk, BE | 1 |
Chen, D; Cui, S; Deng, X; Gong, G; Liu, J; Shi, J; Xu, Y; Yang, Y; Zhang, X; Zhu, Q | 1 |
Fu, G; Liu, Z; Wang, Y; Yin, L; Zhang, K | 1 |
Senoh, M; Sunami, K; Yokota, Y; Yoshioka, T | 1 |
Chen, G; Ding, W; Li, K; Ma, D; Nansubuga, F; Wei, J; Weng, D; Wu, P; Yang, J; Yu, R | 1 |
Bersinger, S; Lagarde, K; Marlu, R; Payen, JF; Pernod, G | 1 |
Guo, Y; Huang, Z; Jia, L; Xing, G; Yun, X; Zou, Z | 1 |
Gamberini, L; Laici, C; Loforte, A; Ravaioli, M; Siniscalchi, A | 1 |
Greinacher, A; Heid, J; Katus, HA; Müller, OJ | 1 |
Gleichgerrcht, E; Lim, MY; Turan, TN | 1 |
Cao, Z; Han, X; Huang, X; Lin, J; Pu, Z; Ren, K; Sun, W; Tian, L; Wang, Y; Xu, J; Zhang, S; Zhou, W | 1 |
Arays, R; McCarthy, P; Shmookler, AD | 1 |
Dai, G; Liu, Q; Sun, L; Wang, C | 1 |
Pötzsch, B | 1 |
Asada, Y; Harada, A; Hattori, K; Inoue, O; Iwakiri, T; Kitazawa, T; Matsuda, S; Matsumoto, T; Matsuura, Y; Okuyama, N; Shima, M; Sugita, C; Yamashita, A | 1 |
Dee, B; Gulbis, A; Lombardi Thomas, L | 1 |
Arachchillage, DR; Baglin, T; Besser, M; Maclean, R; van Veen, JJ | 1 |
Croci, E; Dentali, F; Giorgi-Pierfranceschi, M; Mumoli, N; Scarpioni, R | 1 |
Al-Mondhiry, HA; Ambrose, A; Botti, JJ; Vaida, SJ; Young, SK | 1 |
Maldonado, A | 1 |
Fries, D | 2 |
Hanson, GW; Malias, MA; Mitchell, GA; Sparkman, GM; Stowe, CL; Terneus, WF; Wellborn-Kim, JJ | 1 |
Carlson, KB; DeSancho, MT; Mallik, A | 1 |
Oo, TH | 1 |
FU, FY; LIN, ZQ; LIU, ZJ; PAN, CQ; ZHOU, ZX | 1 |
Ebina, Y; Miyata, S; Morita, H; Sonoyama, A; Tanimura, K; Yamada, H | 1 |
Knovich, MA; Lesser, GJ; Strowd, RE | 1 |
Bay, C; Bentz, S; Memari, S; Nowroozi, S; Sharifi, M; Valeros, G | 1 |
Ahmed, S; Karim, A; Mattana, J; Patel, D; Siddiqui, R | 1 |
Kaplan, KL | 1 |
Dager, WE; White, RH | 1 |
Bauersachs, R; Brehme, S; Caspary, L; Creutzig, A; Harenberg, J; Hoffmann, U; Landgraf, H; Schellong, S | 1 |
Bhatt, DL; Gurm, HS | 1 |
Bozic, M; Budihna, MV; Cerne, M; Drevensek, G; Peternel, L; Stalc, A; Stegnar, M; Urleb, U; Zega, A | 1 |
Fanikos, JR; Kubiak, DW; Szumita, PM | 1 |
Hursting, MJ; Kelton, JG; Lewis, BE; Matthai, WH | 1 |
Eto, T; Gondo, H; Hamasaki, N; Ichimiya, H; Kato, K; Kawamoto, M; Kayamori, Y; Muta, T; Okamura, T; Shibuya, T; Urata, M; Wada, Y; Yamanaka, M | 1 |
Büller, HR; Di Nisio, M; Middeldorp, S | 1 |
Hyers, TM | 1 |
Dager, W; Spinler, SA | 1 |
Kloecker, GH; Laber, DA; Martin, ME | 1 |
Warkentin, TE | 1 |
Berry, CN; Girardot, C; Lechaire, I; Lunven, C; O'Connor, SE | 1 |
Iwamoto, M; Morishita, K | 1 |
Fukazawa, T; Goto, Y; Hayashi, H; Inoue, Y; Komatsu, Y | 1 |
Berry, CN; Girard, D; Lecoffre, C; Lochot, S; Visconte, C | 1 |
Cho, J; Dan, T; Kim, H; Koga, T; Koo, B; Seo, H; Yoshida, S; Yun, C | 1 |
Cho, JH; Dan, T; Kim, HY; Koga, T; Koo, BA; Seo, HS; Yun, CH | 1 |
10 review(s) available for mci 9038 and Venous Thrombosis
Article | Year |
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Argatroban: for a few selected patients.
Topics: Anticoagulants; Antithrombins; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Drug Interactions; Drug Substitution; Hemorrhage; Heparin; Heparitin Sulfate; Humans; Patient Selection; Pipecolic Acids; Risk Assessment; Risk Factors; Sulfonamides; Thrombocytopenia; Treatment Outcome; Venous Thrombosis | 2013 |
[Anticoagulation].
Topics: Administration, Oral; Anticoagulants; Antithrombins; Arginine; Arrhythmias, Cardiac; Blood Coagulation Tests; Factor Xa Inhibitors; Hemorrhage; Heparin; Heparinoids; Hirudins; Humans; Infusions, Intravenous; Orthopedic Procedures; Peptide Fragments; Pipecolic Acids; Postoperative Complications; Pulmonary Embolism; Recombinant Proteins; Risk Factors; Secondary Prevention; Sulfonamides; Thromboembolism; Treatment Outcome; Venous Thrombosis; Vitamin K | 2013 |
Successful use of argatroban during the third trimester of pregnancy: case report and review of the literature.
Topics: Adult; Anticoagulants; Arginine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gravidity; Humans; Infant, Newborn; Infusions, Intravenous; Pipecolic Acids; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Third; Purpura, Thrombocytopenic, Idiopathic; Sulfonamides; Treatment Outcome; Venous Thrombosis | 2008 |
[Anticoagulation in critically ill patient].
Topics: Anticoagulants; Arginine; Biological Availability; Blood Coagulation Tests; Contraindications; Critical Care; Drug Monitoring; Heparin; Heparin, Low-Molecular-Weight; Humans; Pipecolic Acids; Pulmonary Embolism; Risk Factors; Sepsis; Shock, Septic; Sulfonamides; Venous Thrombosis | 2009 |
Thrombosis prophylaxis in critically ill patients.
Topics: Anticoagulants; Arginine; Biological Availability; Chromosome Breakage; Chromosome Disorders; Critical Care; Dose-Response Relationship, Drug; Drug Resistance; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Infusions, Intravenous; Injections, Subcutaneous; Pipecolic Acids; Recombinant Proteins; Risk Factors; Sepsis; Severity of Illness Index; Shock, Septic; Sulfonamides; Thrombin; Thrombocytopenia; Venous Thrombosis | 2011 |
Direct thrombin inhibitors.
Topics: Antithrombins; Arginine; Coronary Disease; Half-Life; Hirudins; Humans; Metabolic Clearance Rate; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin; Venous Thrombosis | 2003 |
[Prevention and treatment of deep vein thrombosis with ximelagatran].
Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Fondaparinux; Glycine; Heparin; Hirudin Therapy; Humans; Pipecolic Acids; Polysaccharides; Prodrugs; Sulfonamides; Thrombin; Venous Thrombosis | 2004 |
Thrombin, an ideal target for pharmacological inhibition: a review of direct thrombin inhibitors.
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Atrial Fibrillation; Azetidines; Benzylamines; Clinical Trials as Topic; Coronary Disease; Heparin; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Syndrome; Thrombin; Thromboembolism; Thrombosis; Venous Thrombosis | 2005 |
Heparin and other rapidly acting anticoagulants.
Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Embolism; Enzyme Inhibitors; Fondaparinux; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Venous Thrombosis | 2005 |
Argatroban for anticoagulation during cardiac surgery.
Topics: Adult; Aged; Anticoagulants; Arginine; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Drug Monitoring; Endocarditis, Bacterial; Female; Heart Valve Prosthesis Implantation; Heparin; Humans; Intra-Aortic Balloon Pumping; Intraoperative Complications; Male; Middle Aged; Mitral Valve; Pipecolic Acids; Postoperative Complications; Retrospective Studies; Staphylococcal Infections; Subclavian Vein; Sulfonamides; Thrombosis; Venous Thrombosis; Warfarin; Whole Blood Coagulation Time | 2007 |
4 trial(s) available for mci 9038 and Venous Thrombosis
Article | Year |
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Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif.
Topics: Amino Acid Motifs; Animals; Anticoagulants; Blood Pressure; Caco-2 Cells; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Double-Blind Method; Electrocardiography; Female; Fibrinolytic Agents; Guanidines; Guinea Pigs; Heart Rate; Hemodynamics; Humans; In Vitro Techniques; Male; Microsomes, Liver; Models, Molecular; Pyrazines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Structure-Activity Relationship; Thrombin; Venous Thrombosis | 2010 |
Efficiency and safety evaluation of prophylaxes for venous thrombosis after gynecological surgery.
Topics: Anticoagulants; Arginine; Endometrial Neoplasms; Female; Gynecologic Surgical Procedures; Heparin, Low-Molecular-Weight; Humans; Injections, Intravenous; Middle Aged; Ovarian Neoplasms; Pipecolic Acids; Postoperative Complications; Risk Factors; Sulfonamides; Uterine Cervical Neoplasms; Venous Thrombosis | 2020 |
[Efficacy of regional administration of urokinase and argatroban via small saphenous vein catheter for treatment of acute deep venous thrombosis in the lower limb].
Topics: Adult; Arginine; Female; Fibrinolytic Agents; Humans; Injections, Intravenous; Lower Extremity; Male; Middle Aged; Pipecolic Acids; Saphenous Vein; Sulfonamides; Urokinase-Type Plasminogen Activator; Venous Thrombosis; Young Adult | 2011 |
Argatroban anticoagulation in patients with a history of heparin-induced thrombocytopenia.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Coronary Disease; Female; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Pulmonary Embolism; Sulfonamides; Thrombocytopenia; Treatment Outcome; Venous Thrombosis | 2005 |
39 other study(ies) available for mci 9038 and Venous Thrombosis
Article | Year |
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Efficacious and orally bioavailable thrombin inhibitors based on a 2,5-thienylamidine at the P1 position: discovery of N-carboxymethyl-d-diphenylalanyl-l-prolyl[(5-amidino-2-thienyl)methyl]amide.
Topics: Administration, Oral; Amidines; Animals; Anticoagulants; Biological Availability; Crystallography, X-Ray; Dipeptides; Dogs; Drug Stability; Fibrinolytic Agents; Fluoroacetates; Haplorhini; Humans; In Vitro Techniques; Liver; Male; Models, Molecular; Protease Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfanilamides; Thrombin; Venous Thrombosis | 2003 |
In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
Topics: Animals; Anticoagulants; Binding Sites; Cattle; Crystallography, X-Ray; Dogs; Drug Design; Electrocardiography; Fibrinolytic Agents; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Hypotension; In Vitro Techniques; Ketones; Models, Molecular; Molecular Structure; Oligopeptides; Platelet Aggregation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thrombin; Trypsin; Venous Thrombosis | 2005 |
Design, synthesis and antithrombotic evaluation of novel non-peptide thrombin inhibitors.
Topics: Animals; Dose-Response Relationship, Drug; Drug Design; Fibrinolytic Agents; Humans; Male; Molecular Structure; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thrombin; Venous Thrombosis | 2017 |
Dabigatran Use after Argatroban for Heparin-induced Thrombocytopenia with Thrombosis: A Case Series and Literature Review.
Topics: Aged; Anticoagulants; Antithrombins; Arginine; Dabigatran; Drug Therapy, Combination; Fatal Outcome; Female; Gastrointestinal Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Count; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2022 |
Successful intravenous administration of argatroban in the management of heparin-resistant and surgery-resistant mesenteric vein thrombosis.
Topics: Administration, Intravenous; Aged; Antithrombins; Arginine; Female; Humans; Mesenteric Vascular Occlusion; Mesenteric Veins; Pipecolic Acids; Portal Vein; Splenic Vein; Sulfonamides; Treatment Outcome; Venous Thrombosis | 2019 |
Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia.
Topics: Antithrombins; Arginine; Cerebral Veins; ChAdOx1 nCoV-19; COVID-19 Vaccines; Drug Therapy, Combination; Female; Fondaparinux; Humans; Immunoglobulins, Intravenous; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Tomography, X-Ray Computed; Venous Thrombosis; Young Adult | 2021 |
Safety and effectiveness of argatroban versus heparin for preventing venous thromboembolism after lumbar decompressive surgery.
Topics: Adult; Aged; Anticoagulants; Arginine; Decompression, Surgical; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Incidence; Lumbar Vertebrae; Male; Middle Aged; Pipecolic Acids; Platelet Aggregation Inhibitors; Postoperative Complications; Quality of Life; Retrospective Studies; Sulfonamides; Venous Thromboembolism; Venous Thrombosis | 2017 |
Thrombolysis for acute pulmonary embolism after major hepatic surgery.
Topics: Acute Disease; Adenocarcinoma; Appendiceal Neoplasms; Arginine; Atrial Fibrillation; Bronchoscopy; Catheters; Colectomy; Computed Tomography Angiography; Diagnosis, Differential; Electric Countershock; Fibrinolytic Agents; Heparin; Hepatectomy; Humans; Infusions, Intravenous; Intubation, Intratracheal; Liver Neoplasms; Lung; Male; Middle Aged; Pipecolic Acids; Postoperative Complications; Pulmonary Embolism; Sulfonamides; Thrombocytopenia; Thrombolytic Therapy; Tissue Plasminogen Activator; Troponin I; Ultrasonography; Venous Thrombosis | 2017 |
Idiopathic catastrophic thrombosis with happy ending.
Topics: Anticoagulants; Antithrombins; Arginine; Awareness; Blood Coagulation Tests; Coronary Artery Bypass; Heparin; Humans; Male; Middle Aged; Phenprocoumon; Pipecolic Acids; Platelet Aggregation Inhibitors; ST Elevation Myocardial Infarction; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome; Ultrasonography; Venous Thrombosis | 2017 |
Cerebral Venous Sinus Thrombosis Due to Low-molecular-weight Heparin-induced Thrombocytopenia.
Topics: Anticoagulants; Arginine; Female; Heparin, Low-Molecular-Weight; Humans; Middle Aged; Pipecolic Acids; Platelet Count; Sulfonamides; Thrombocytopenia; Thrombosis; Venous Thrombosis | 2017 |
Thrombosis in the portal venous system caused by hypereosinophilic syndrome: A case report.
Topics: Arginine; Critical Illness; Drug Therapy, Combination; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Heparin; Humans; Hypereosinophilic Syndrome; Male; Pipecolic Acids; Plasma Exchange; Platelet Aggregation Inhibitors; Portal System; Pulmonary Eosinophilia; Sulfonamides; Tissue Plasminogen Activator; Tomography, X-Ray Computed; Urokinase-Type Plasminogen Activator; Venous Thrombosis; Young Adult | 2018 |
Inpatient management strategies in a severe case of heparin-induced thrombocytopenia.
Topics: Aged; Arginine; Coronary Artery Bypass; Female; Fondaparinux; Heparin; Humans; Pipecolic Acids; Platelet Count; Platelet Transfusion; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2019 |
Application of thrombelastography in primary total knee and total hip replacement: a prospective 87 patients study.
Topics: Anticoagulants; Arginine; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Female; Humans; Male; Middle Aged; Partial Thromboplastin Time; Perioperative Care; Pipecolic Acids; Postoperative Care; Preoperative Care; Prospective Studies; Prothrombin Time; Pulmonary Embolism; Rivaroxaban; Sulfonamides; Thrombelastography; Thrombophilia; Venous Thrombosis | 2019 |
Elevated plasma factor VIII enhances venous thrombus formation in rabbits: contribution of factor XI, von Willebrand factor and tissue factor.
Topics: Animals; Antibodies, Blocking; Arginine; Blood Platelets; Factor VIII; Factor XI; Hemostasis; Humans; Jugular Veins; Male; Pipecolic Acids; Platelet Aggregation; Rabbits; Sulfonamides; Thrombin; Thromboplastin; Venous Thrombosis; von Willebrand Factor | 2013 |
Heparin-induced thrombocytopenia.
Topics: Anticoagulants; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Heparin; Heparitin Sulfate; Humans; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Count; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2013 |
Use of argatroban and catheter-directed thrombolysis with alteplase in an oncology patient with heparin-induced thrombocytopenia with thrombosis.
Topics: Antithrombins; Arginine; Autografts; Catheterization; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombolytic Therapy; Tissue Plasminogen Activator; Venous Thrombosis | 2014 |
Combined factor IIa and Xa inhibitor therapy for thrombosis whilst on therapeutic anticoagulant.
Topics: Adult; Aged; Anticoagulants; Antithrombins; Arginine; Dabigatran; Factor Xa Inhibitors; Female; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Neoplasms; Pipecolic Acids; Pyrazoles; Pyridones; Recurrence; Rivaroxaban; Sulfonamides; Venous Thrombosis | 2016 |
Argatroban for Treatment of Heparin-Induced Thrombocytopenia and Thrombosis in a Patient with Multiple Myeloma Undergoing Hemodialysis.
Topics: Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Dalteparin; Female; Humans; Multiple Myeloma; Partial Thromboplastin Time; Pipecolic Acids; Renal Dialysis; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2016 |
Argatroban and catheter-directed thrombolysis with alteplase for limb- and graft-threatening thromboses in a patient with a history of HIT.
Topics: Aged; Antibodies, Anticardiolipin; Anticoagulants; Arginine; Catheterization; Contraindications; Drug Therapy, Combination; Femoral Vein; Heparin; Humans; Iliac Vein; Infusions, Intravenous; Ischemia; Kidney; Kidney Transplantation; Male; Pipecolic Acids; Popliteal Vein; Postoperative Complications; Protein S Deficiency; Purpura, Thrombocytopenic, Idiopathic; Renal Veins; Sulfonamides; Thrombolytic Therapy; Thrombophilia; Tissue Plasminogen Activator; Vena Cava Filters; Venous Thrombosis; Warfarin | 2009 |
Fondaparinux therapy in a hemodialysis patient with heparin-induced thrombocytopenia type II.
Topics: Aged, 80 and over; Anticoagulants; Arginine; Coronary Artery Bypass; Female; Fondaparinux; Heparin; Humans; Mitral Valve; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Count; Polysaccharides; Renal Dialysis; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2010 |
A patient with 'spontaneous' heparin-induced thrombocytopenia and thrombosis after undergoing knee replacement.
Topics: Anticoagulants; Antithrombins; Arginine; Arthroplasty, Replacement, Knee; Autoantibodies; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Factor 4; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2011 |
Thrombolytic therapy and thrombectomy in phlegmasia cerulea dolens.
Topics: Anticoagulants; Antithrombins; Arginine; Fibrinolytic Agents; Heparin; Hirudins; Humans; Pipecolic Acids; Platelet Aggregation Inhibitors; Recombinant Proteins; Sulfonamides; Thrombectomy; Thrombocytopenia; Time Factors; Venous Thrombosis | 2010 |
Argatroban therapy for heparin-induced thrombocytopenia during pregnancy in a woman with hereditary antithrombin deficiency.
Topics: Adult; Anticoagulants; Antithrombins; Arginine; Blood Coagulation Disorders, Inherited; Female; Heparin; Humans; Male; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2012 |
The therapeutic management of bleeding and thrombotic disorders complicating CNS malignancies.
Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Bevacizumab; Central Nervous System Neoplasms; Fondaparinux; Glioblastoma; Glioma; Hemorrhage; Heparin, Low-Molecular-Weight; Hirudins; Humans; Pipecolic Acids; Polysaccharides; Postoperative Complications; Pulmonary Embolism; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Vena Cava Filters; Venous Thromboembolism; Venous Thrombosis; Warfarin | 2012 |
Catheter-directed thrombolysis with argatroban and tPA for massive iliac and femoropopliteal vein thrombosis.
Topics: Arginine; Catheterization, Peripheral; Catheters; Drug Therapy, Combination; Female; Femoral Vein; Fibrinolytic Agents; Follow-Up Studies; Humans; Iliac Vein; Male; Middle Aged; Phlebography; Pipecolic Acids; Platelet Aggregation Inhibitors; Popliteal Vein; Recurrence; Severity of Illness Index; Sulfonamides; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome; Venous Thrombosis | 2013 |
Low-molecular weight heparin: treatment failure in a patient with primary antiphospholipid antibody syndrome.
Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Arginine; Arm; Enoxaparin; Female; Folic Acid; Heparin, Low-Molecular-Weight; Humans; International Normalized Ratio; Pipecolic Acids; Pulmonary Embolism; Sulfonamides; Treatment Failure; Treatment Outcome; Venous Thrombosis; Warfarin | 2002 |
Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHD.
Topics: Acute Disease; Adult; Anticoagulants; Arginine; Fatal Outcome; Heparin; Humans; Infusions, Intravenous; Liver Failure; Male; Pipecolic Acids; Renal Dialysis; Renal Insufficiency; Sulfonamides; Thrombocytopenia; Venous Thrombosis | 2003 |
Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models.
Topics: Administration, Oral; Animals; Anticoagulants; Arginine; Blood Coagulation Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fibrinolytic Agents; Injections, Subcutaneous; Male; Nadroparin; Phenylalanine; Pipecolic Acids; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfonamides; Thrombin; Thrombophilia; Vena Cava, Inferior; Venous Thrombosis | 2005 |
Extensive prolongation of aPTT with argatroban in an elderly patient with improving renal function, normal hepatic enzymes, and metastatic lung cancer.
Topics: Aged; Anticoagulants; Arginine; Humans; Infusions, Intravenous; Kidney; Kidney Function Tests; Liver; Liver Function Tests; Lung Neoplasms; Male; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Time Factors; Venous Thrombosis | 2005 |
Successful therapy with argatroban for superior mesenteric vein thrombosis in a patient with congenital antithrombin deficiency.
Topics: Adult; Antithrombin III Deficiency; Arginine; DNA Mutational Analysis; Female; Frameshift Mutation; Heterozygote; Humans; Mesenteric Vascular Occlusion; Mesenteric Veins; Pipecolic Acids; Salvage Therapy; Sulfonamides; Treatment Outcome; Venous Thrombosis | 2005 |
Direct thrombin inhibitors.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Benzimidazoles; Blood Coagulation; Dabigatran; Heart Diseases; Heparin; Humans; Pipecolic Acids; Prodrugs; Pyridines; Sulfonamides; Thrombin; Thromboembolism; Thrombosis; Venous Thrombosis | 2005 |
Comment: extensive prolongation of aPTT with argatroban in an elderly patient with improving renal function, normal hepatic enzymes, and metastatic lung cancer.
Topics: Aged; Anticoagulants; Arginine; Humans; International Normalized Ratio; Kidney; Kidney Function Tests; Liver; Lung Neoplasms; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Venous Thrombosis; Warfarin | 2005 |
Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT)--bridging the River Coumarin.
Topics: Acute Disease; Anticoagulants; Arginine; Blood Coagulation; Factor Xa Inhibitors; Fondaparinux; Hemorrhage; Heparin; Hirudins; Humans; International Normalized Ratio; Pipecolic Acids; Platelet Count; Polysaccharides; Recombinant Proteins; Research Design; Sulfonamides; Thrombin; Thrombocytopenia; Treatment Outcome; Venous Thrombosis; Warfarin | 2008 |
Antithrombotic activity of a monoclonal antibody inducing the substrate form of plasminogen activator inhibitor type 1 in rat models of venous and arterial thrombosis.
Topics: Animals; Antibodies, Monoclonal; Anticoagulants; Arginine; Bleeding Time; Cross Reactions; Fibrinolytic Agents; Heparin; Humans; Male; Pipecolic Acids; Plasminogen Activator Inhibitor 1; Platelet Aggregation Inhibitors; Rats; Sulfonamides; Thrombosis; Venous Thrombosis | 1998 |
Synergistic antithrombotic effects of argatroban and ticlopidine in the rat venous thrombosis model.
Topics: Animals; Anticoagulants; Antithrombins; Arginine; Drug Synergism; Male; Pipecolic Acids; Rats; Rats, Wistar; Sulfonamides; Ticlopidine; Venous Thrombosis | 1998 |
Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.
Topics: Amino Acid Sequence; Animals; Arginine; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; Chlorides; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Glass; Hemorrhage; Heparin; Hirudin Therapy; Hirudins; Molecular Sequence Data; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Sulfonamides; Thrombin; Thrombosis; Vena Cava, Inferior; Venous Thrombosis | 1999 |
Activity of a sub-cutaneously administered novel mixed micellar formulation of argatroban in rat and rabbit models of venous thrombosis.
Topics: Animals; Anticoagulants; Antithrombins; Arginine; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Coagulation Tests; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Drug Evaluation, Preclinical; Hemostatics; Heparin; Injections, Subcutaneous; Male; Micelles; Pipecolic Acids; Rabbits; Rats; Sulfonamides; Thromboplastin; Venous Thrombosis | 2000 |
In vitro and in vivo studies of AT-1362, a newly synthesized and orally active inhibitor of thrombin.
Topics: Administration, Oral; Amidines; Animals; Arginine; Binding, Competitive; Bleeding Time; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferrous Compounds; Fibrinolytic Agents; Humans; Male; Molecular Structure; Partial Thromboplastin Time; Pipecolic Acids; Protein Binding; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombin; Vascular Patency; Venous Thrombosis | 2000 |
The antithrombotic efficacy of AT-1459, a novel, direct thrombin inhibitor, in rat models of venous and arterial thrombosis.
Topics: Administration, Oral; Amidines; Animals; Arginine; Azepines; Bleeding Time; Carotid Artery Thrombosis; Dalteparin; Drug Evaluation, Preclinical; Fibrinolytic Agents; Hemorrhage; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Molecular Structure; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombin; Vena Cava, Inferior; Venous Thrombosis; Warfarin | 2001 |