mazindol has been researched along with Substance Withdrawal Syndrome in 5 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alevizos, B | 1 |
| Cass, WA | 1 |
| Gerhardt, GA | 1 |
| Gillespie, K | 1 |
| Curella, P | 1 |
| Mayfield, RD | 1 |
| Zahniser, NR | 1 |
| Stine, SM | 1 |
| Krystal, JH | 1 |
| Kosten, TR | 1 |
| Charney, DS | 1 |
| Sharpe, LG | 1 |
| Pilotte, NS | 1 |
| Mitchell, WM | 1 |
| De Souza, EB | 1 |
| Yutrzenka, GJ | 1 |
| Patrick, GA | 1 |
| Rosenberger, W | 1 |
1 trial available for mazindol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Mazindol treatment for cocaine dependence.
Topics: Adult; Central Nervous System Stimulants; Cocaine; Double-Blind Method; Female; Humans; Male; Mazind | 1995 |
4 other studies available for mazindol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Dependence and chronic psychosis with D-nor-pseudoephedrine.
Topics: Antipsychotic Agents; Appetite; Appetite Depressants; Benzodiazepines; Central Nervous System Stimul | 2003 |
Reduced clearance of exogenous dopamine in rat nucleus accumbens, but not in dorsal striatum, following cocaine challenge in rats withdrawn from repeated cocaine administration.
Topics: Animals; Autoradiography; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists | 1993 |
Withdrawal of repeated cocaine decreases autoradiographic [3H]mazindol-labelling of dopamine transporter in rat nucleus accumbens.
Topics: Animals; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Densitometry; Desipramine; Dop | 1991 |
Substitution of psychoactive drugs in pentobarbital-dependent rats.
Topics: Animals; Antidepressive Agents; Arousal; Body Weight; Brain; Bromazepam; Bupropion; Diazepam; Dose-R | 1990 |