mazindol has been researched along with Idiopathic Hypersomnia in 2 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Idiopathic Hypersomnia: A sleep disorder of central nervous system origin characterized by prolonged nocturnal sleep and periods of daytime drowsiness. Affected individuals experience difficulty with awakening in the morning and may have associated sleep drunkenness, automatic behaviors, and memory disturbances. This condition differs from narcolepsy in that daytime sleep periods are longer, there is no association with CATAPLEXY, and the multiple sleep latency onset test does not record sleep-onset rapid eye movement sleep. (From Chokroverty, Sleep Disorders Medicine, 1994, pp319-20; Psychiatry Clin Neurosci 1998 Apr:52(2):125-129)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mazindol is a tricyclic, anorectic, non-amphetamine stimulant used in narcolepsy and obesity since 1970." | 9.17 | Mazindol in narcolepsy and idiopathic and symptomatic hypersomnia refractory to stimulants: a long-term chart review. ( Arnulf, I; Bayard, S; Cock, VC; Dauvilliers, Y; Franco, P; Inocente, CO; Konofal, E; Lecendreux, M; Leu-Semenescu, S; Nittur, N; Scholtz, S, 2013) |
| "Mazindol is a tricyclic, anorectic, non-amphetamine stimulant used in narcolepsy and obesity since 1970." | 5.17 | Mazindol in narcolepsy and idiopathic and symptomatic hypersomnia refractory to stimulants: a long-term chart review. ( Arnulf, I; Bayard, S; Cock, VC; Dauvilliers, Y; Franco, P; Inocente, CO; Konofal, E; Lecendreux, M; Leu-Semenescu, S; Nittur, N; Scholtz, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arnulf, I | 2 |
| Leu-Semenescu, S | 2 |
| Dodet, P | 1 |
| Nittur, N | 1 |
| Konofal, E | 1 |
| Dauvilliers, Y | 1 |
| Franco, P | 1 |
| Cock, VC | 1 |
| Inocente, CO | 1 |
| Bayard, S | 1 |
| Scholtz, S | 1 |
| Lecendreux, M | 1 |
1 review available for mazindol and Idiopathic Hypersomnia
| Article | Year |
|---|---|
Precision Medicine for Idiopathic Hypersomnia.
Topics: Central Nervous System Stimulants; Clarithromycin; Flumazenil; GABA Modulators; Humans; Idiopathic H | 2019 |
1 trial available for mazindol and Idiopathic Hypersomnia
| Article | Year |
|---|---|
Mazindol in narcolepsy and idiopathic and symptomatic hypersomnia refractory to stimulants: a long-term chart review.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cataplexy; Central Nervous System Stimulants; Child; Female | 2013 |