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mazindol and Hypothermia

mazindol has been researched along with Hypothermia in 2 studies

Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"A series of 5-aryl-2,3,5,6-tetrahydroimidazo[2,1-a]isoquinolin-5-ols was prepared and evaluated for potential antidepressant activity in the reserpine-induced hypothermia model and selected central nervous system and autonomic activity tests."3.66Antidepressant activity of 5-aryl-2,3,5,6-tetrahydroimidazo[2,1-a]isoquinolin-5-ols. ( Gogerty, JH; Houlihan, WJ; Parrino, VA; Ryan, E, 1983)
" To verify this hypothesis, we investigated the influence of hypothermia on the toxic activity of both neurotoxins."1.32Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons. ( Cleren, C; Costentin, J; Naudin, B, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Houlihan, WJ1
Gogerty, JH1
Parrino, VA1
Ryan, E1
Cleren, C1
Naudin, B1
Costentin, J1

Other Studies

2 other studies available for mazindol and Hypothermia

ArticleYear
Antidepressant activity of 5-aryl-2,3,5,6-tetrahydroimidazo[2,1-a]isoquinolin-5-ols.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:5

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Hypothermia; Imi

1983
Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
    Brain research, 2003, Nov-07, Volume: 989, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Binding Si

2003