mazindol has been researched along with Hypothermia in 2 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A series of 5-aryl-2,3,5,6-tetrahydroimidazo[2,1-a]isoquinolin-5-ols was prepared and evaluated for potential antidepressant activity in the reserpine-induced hypothermia model and selected central nervous system and autonomic activity tests." | 3.66 | Antidepressant activity of 5-aryl-2,3,5,6-tetrahydroimidazo[2,1-a]isoquinolin-5-ols. ( Gogerty, JH; Houlihan, WJ; Parrino, VA; Ryan, E, 1983) |
| " To verify this hypothesis, we investigated the influence of hypothermia on the toxic activity of both neurotoxins." | 1.32 | Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons. ( Cleren, C; Costentin, J; Naudin, B, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Houlihan, WJ | 1 |
| Gogerty, JH | 1 |
| Parrino, VA | 1 |
| Ryan, E | 1 |
| Cleren, C | 1 |
| Naudin, B | 1 |
| Costentin, J | 1 |
2 other studies available for mazindol and Hypothermia
| Article | Year |
|---|---|
Antidepressant activity of 5-aryl-2,3,5,6-tetrahydroimidazo[2,1-a]isoquinolin-5-ols.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Hypothermia; Imi | 1983 |
Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Binding Si | 2003 |