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mazindol and Gelineau Syndrome

mazindol has been researched along with Gelineau Syndrome in 11 studies

Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.

Research Excerpts

ExcerptRelevanceReference
"Mazindol is a tricyclic, anorectic, non-amphetamine stimulant used in narcolepsy and obesity since 1970."9.17Mazindol in narcolepsy and idiopathic and symptomatic hypersomnia refractory to stimulants: a long-term chart review. ( Arnulf, I; Bayard, S; Cock, VC; Dauvilliers, Y; Franco, P; Inocente, CO; Konofal, E; Lecendreux, M; Leu-Semenescu, S; Nittur, N; Scholtz, S, 2013)
"Twenty patients with the narcoleptic syndrome were treated separately with dexamphetamine sulphate tablets 10 and 30 mg, Dexedrine Spansules 10 mg, mazindol 4 mg, and fencamfamin hydrochloride 60 mg daily."6.66Amphetamine, mazindol, and fencamfamin in narcolepsy. ( Brincat, S; Parkes, JD; Schachter, M; Shindler, J, 1985)
"Selegiline was compared to no treatment (7 subjects) or conventional central stimulant drugs, including dexamphetamine or mazindol (14 subjects)."5.27Selegiline in narcolepsy. ( Jenner, P; Langdon, N; Lock, CB; Parkes, JD; Roselaar, SE, 1987)
"Thirty-four subjects with the narcoleptic syndrome were treated with mazindol 3--8 mg daily for 1 year."5.26Mazindol in the treatment of narcolepsy. ( Parkes, JD; Schachter, M, 1979)
"Mazindol is a tricyclic, anorectic, non-amphetamine stimulant used in narcolepsy and obesity since 1970."5.17Mazindol in narcolepsy and idiopathic and symptomatic hypersomnia refractory to stimulants: a long-term chart review. ( Arnulf, I; Bayard, S; Cock, VC; Dauvilliers, Y; Franco, P; Inocente, CO; Konofal, E; Lecendreux, M; Leu-Semenescu, S; Nittur, N; Scholtz, S, 2013)
"Twenty patients with the narcoleptic syndrome were treated separately with dexamphetamine sulphate tablets 10 and 30 mg, Dexedrine Spansules 10 mg, mazindol 4 mg, and fencamfamin hydrochloride 60 mg daily."2.66Amphetamine, mazindol, and fencamfamin in narcolepsy. ( Brincat, S; Parkes, JD; Schachter, M; Shindler, J, 1985)
"Onset of narcolepsy is unusual at this age and the temporal relationship following radiotherapy suggests this treatment was implicated."1.32Acquired narcolepsy in an acromegalic patient who underwent pituitary irradiation. ( de Silva, RN; Dempsey, OJ; Douglas, NJ; McGeoch, P, 2003)
"Selegiline was compared to no treatment (7 subjects) or conventional central stimulant drugs, including dexamphetamine or mazindol (14 subjects)."1.27Selegiline in narcolepsy. ( Jenner, P; Langdon, N; Lock, CB; Parkes, JD; Roselaar, SE, 1987)
"Thirty-four subjects with the narcoleptic syndrome were treated with mazindol 3--8 mg daily for 1 year."1.26Mazindol in the treatment of narcolepsy. ( Parkes, JD; Schachter, M, 1979)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nittur, N1
Konofal, E1
Dauvilliers, Y1
Franco, P1
Leu-Semenescu, S1
Cock, VC1
Inocente, CO1
Bayard, S1
Scholtz, S1
Lecendreux, M1
Arnulf, I1
Dempsey, OJ1
McGeoch, P1
de Silva, RN1
Douglas, NJ1
Vespignani, H2
Barroche, G2
Escaillas, JP1
Weber, M2
Parkes, JD4
Schachter, M2
Alvarez, B1
Dahlitz, M1
Grimshaw, J1
Lange, KW1
Shindler, J1
Brincat, S1
Roselaar, SE1
Langdon, N1
Lock, CB1
Jenner, P1
Iijima, S1
Sugita, Y1
Teshima, Y1
Hishikawa, Y1
Atlas, P1
Salín-Pascual, RJ1
de la Fuente, JR1

Reviews

1 review available for mazindol and Gelineau Syndrome

ArticleYear
[Narcolepsy].
    Deutsche medizinische Wochenschrift (1946), 1990, Aug-17, Volume: 115, Issue:33

    Topics: Adolescent; Adult; Amphetamine; Cataplexy; Child; Clomipramine; Diagnosis, Differential; Female; Hum

1990

Trials

2 trials available for mazindol and Gelineau Syndrome

ArticleYear
Mazindol in narcolepsy and idiopathic and symptomatic hypersomnia refractory to stimulants: a long-term chart review.
    Sleep medicine, 2013, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Blood Pressure; Cataplexy; Central Nervous System Stimulants; Child; Female

2013
Amphetamine, mazindol, and fencamfamin in narcolepsy.
    British medical journal (Clinical research ed.), 1985, Apr-20, Volume: 290, Issue:6476

    Topics: Adult; Aged; Amphetamines; Central Nervous System Stimulants; Female; Humans; Indoles; Male; Mazindo

1985

Other Studies

8 other studies available for mazindol and Gelineau Syndrome

ArticleYear
Acquired narcolepsy in an acromegalic patient who underwent pituitary irradiation.
    Neurology, 2003, Aug-26, Volume: 61, Issue:4

    Topics: Acromegaly; Carrier Proteins; Central Nervous System Stimulants; Humans; Intracellular Signaling Pep

2003
Importance of mazindol in the treatment of narcolepsy.
    Sleep, 1984, Volume: 7, Issue:3

    Topics: Female; Humans; Indoles; Male; Mazindol; Narcolepsy

1984
Mazindol in the treatment of narcolepsy.
    Acta neurologica Scandinavica, 1979, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Aged; Female; Humans; Indoles; Male; Mazindol; Middle Aged; Narcolepsy

1979
Mazindol in long-term treatment of narcolepsy.
    Lancet (London, England), 1991, May-25, Volume: 337, Issue:8752

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Mazindol; Middle Aged; Narcolepsy

1991
Selegiline in narcolepsy.
    Sleep, 1987, Volume: 10, Issue:5

    Topics: Adult; Affect; Aged; Cataplexy; Dextroamphetamine; Humans; Male; Mazindol; Middle Aged; Narcolepsy;

1987
Therapeutic effects of mazindol on narcolepsy.
    Sleep, 1986, Volume: 9, Issue:1 Pt 2

    Topics: Adult; Cataplexy; Female; Humans; Indoles; Male; Mazindol; Middle Aged; Narcolepsy

1986
[Value of mazindol in Gélineau's disease. Apropos of 10 cases].
    Revue d'electroencephalographie et de neurophysiologie clinique, 1986, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Catalepsy; Clomipramine; Drug Therapy, Combination; Female; Humans; Indoles; Male

1986
[Advances in the psychopharmacological management of the narcoleptic patient].
    Acta psiquiatrica y psicologica de America latina, 1985, Volume: 31, Issue:1

    Topics: Animals; Clonidine; Dogs; Humans; Hydroxybutyrates; Indoles; Mazindol; Narcolepsy; Sleep, REM; Sodiu

1985