mazindol has been researched along with Dementia Praecox in 5 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both Parkinson's disease and progressive supranuclear palsy populations were characterized by a marked loss of [3H]mazindol binding sites in the neostriatum (about 75%) and in the nucleus accumbens (about 65%)." | 1.28 | Mesostriatal and mesolimbic dopamine uptake binding sites are reduced in Parkinson's disease and progressive supranuclear palsy: a quantitative autoradiographic study using [3H]mazindol. ( Alvarez, FJ; Chinaglia, G; Palacios, JM; Probst, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carpenter, WT | 1 |
| Breier, A | 1 |
| Buchanan, RW | 1 |
| Kirkpatrick, B | 1 |
| Shepard, P | 1 |
| Weiner, E | 1 |
| McMahon, LR | 1 |
| Cunningham, KA | 1 |
| Chinaglia, G | 1 |
| Alvarez, FJ | 1 |
| Probst, A | 1 |
| Palacios, JM | 1 |
| Dworkin, RH | 1 |
| Opler, LA | 1 |
| Seibyl, JP | 1 |
| Brenner, L | 1 |
| Krystal, JH | 1 |
| Johnson, R | 1 |
| Charney, DS | 1 |
1 trial available for mazindol and Dementia Praecox
| Article | Year |
|---|---|
Mazindol treatment of negative symptoms.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Dopamine Uptake Inhibitors; Double-Blind Method; Fe | 2000 |
4 other studies available for mazindol and Dementia Praecox
| Article | Year |
|---|---|
Role of 5-HT(2a) and 5-HT(2B/2C) receptors in the behavioral interactions between serotonin and catecholamine reuptake inhibitors.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Catecholamines; Depression; D | 2001 |
Mesostriatal and mesolimbic dopamine uptake binding sites are reduced in Parkinson's disease and progressive supranuclear palsy: a quantitative autoradiographic study using [3H]mazindol.
Topics: Aged; Aged, 80 and over; Autoradiography; Basal Ganglia; Carrier Proteins; Corpus Striatum; Dopamine | 1992 |
Simple schizophrenia, negative symptoms, and prefrontal hypodopaminergia.
Topics: Dopamine; Frontal Lobe; Humans; Levodopa; Mazindol; Schizophrenia; Schizophrenic Psychology | 1992 |
Mazindol and cocaine addiction in schizophrenia.
Topics: Adult; Cocaine; Humans; Male; Mazindol; Schizophrenia; Substance-Related Disorders | 1992 |