mazindol has been researched along with Brain Ischemia in 2 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thus, cerebral ischemia that was associated with cell loss in the striatum resulted in a selective reduction of dopamine D1 receptors and not D2 receptors." | 1.29 | Effects of cerebral ischemia on dopamine receptors in the gerbil striatum. ( Araki, T; Fujiwara, T; Itoyama, Y; Kato, H; Kogure, K; Shuto, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Araki, T | 1 |
| Kato, H | 1 |
| Shuto, K | 1 |
| Fujiwara, T | 1 |
| Kogure, K | 1 |
| Itoyama, Y | 1 |
| Przedborski, S | 1 |
| Kostic, V | 1 |
| Jackson-Lewis, V | 1 |
| Cadet, JL | 1 |
| Burke, RE | 1 |
2 other studies available for mazindol and Brain Ischemia
| Article | Year |
|---|---|
Effects of cerebral ischemia on dopamine receptors in the gerbil striatum.
Topics: Animals; Benzamides; Benzazepines; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Dopamine Antago | 1996 |
Effect of unilateral perinatal hypoxic-ischemic brain injury in the rat on dopamine D1 and D2 receptors and uptake sites: a quantitative autoradiographic study.
Topics: Animals; Animals, Newborn; Autoradiography; Benzazepines; Biogenic Amines; Brain Ischemia; Female; H | 1991 |