mazindol has been researched along with Aging in 9 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These findings led us to conclude that the chronic administration of mazindol and methamphetamine have no effects on the antioxidant systems studied either in young (10 months) or in old (23 months) rats." | 1.29 | Antioxidant defense in rat brain after chronic treatment with anorectic drugs. ( Azzalis, LA; Camarini, R; Carlini, EA; D'Almeida, V; Junqueira, VB; Mattei, R, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 8 (88.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prasad, C | 2 |
| Ikegami, H | 1 |
| Shimizu, I | 2 |
| Onaivi, ES | 1 |
| D'Almeida, V | 1 |
| Camarini, R | 1 |
| Azzalis, LA | 1 |
| Mattei, R | 1 |
| Junqueira, VB | 1 |
| Carlini, EA | 1 |
| Araki, T | 1 |
| Kato, H | 1 |
| Shuto, K | 1 |
| Fujiwara, T | 1 |
| Itoyama, Y | 1 |
| Thomas, WS | 1 |
| Neal-Beliveau, BS | 1 |
| Joyce, JN | 3 |
| Guthrie, KM | 1 |
| Pullara, JM | 1 |
| Marshall, JF | 1 |
| Leon, M | 1 |
| Neal, BS | 1 |
| Rao, PA | 1 |
| Molinoff, PB | 1 |
| Battaglia, G | 1 |
| Norman, AB | 1 |
| Creese, I | 1 |
9 other studies available for mazindol and Aging
| Article | Year |
|---|---|
Chronic nicotine intake decelerates aging of nigrostriatal dopaminergic neurons.
Topics: Aging; Animals; Apomorphine; Benzazepines; Binding Sites; Body Weight; Cellular Senescence; Corpus S | 1994 |
Antioxidant defense in rat brain after chronic treatment with anorectic drugs.
Topics: Aging; Animals; Antioxidants; Appetite Depressants; Brain; Catalase; Dopamine Uptake Inhibitors; Glu | 1995 |
Effect of aging on dopaminergic receptors and uptake sites in the rat brain studied by receptor autoradiography.
Topics: Aging; Animals; Autoradiography; Benzamides; Benzazepines; Brain Chemistry; Dopamine Antagonists; Do | 1997 |
There is a limited critical period for dopamine's effects on D1 receptor expression in the developing rat neostriatum.
Topics: Aging; Animals; Animals, Newborn; Benzazepines; Carrier Proteins; Corpus Striatum; Dopamine; Dopamin | 1998 |
Olfactory deprivation increases dopamine D2 receptor density in the rat olfactory bulb.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Benzazepines; Catecholamines; Functional Laterali | 1991 |
Dopamine D1 receptor behavioral responsitivity following selective lesions of the striatal patch compartment during development.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Analysis of Variance; Animals; An | 1991 |
Ontogeny of dopamine D1 and D2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study.
Topics: Aging; Animals; Autoradiography; Basal Ganglia; Benzamides; Benzazepines; Dopamine Antagonists; Fema | 1991 |
Relationship between [3H]mazindol binding to dopamine uptake sites and [3H]dopamine uptake in rat striatum during aging.
Topics: Aging; Animals; Carrier Proteins; Cell Membrane; Corpus Striatum; Dopamine; Dopamine Antagonists; Do | 1991 |
Age-related differential recovery rates of rat striatal D-1 dopamine receptors following irreversible inactivation.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Flupenthixol; Male; Mazindol; Quinolines; Rats; Rats, | 1988 |