Page last updated: 2024-10-30

mazindol and Aging

mazindol has been researched along with Aging in 9 studies

Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" These findings led us to conclude that the chronic administration of mazindol and methamphetamine have no effects on the antioxidant systems studied either in young (10 months) or in old (23 months) rats."1.29Antioxidant defense in rat brain after chronic treatment with anorectic drugs. ( Azzalis, LA; Camarini, R; Carlini, EA; D'Almeida, V; Junqueira, VB; Mattei, R, 1995)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's8 (88.89)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prasad, C2
Ikegami, H1
Shimizu, I2
Onaivi, ES1
D'Almeida, V1
Camarini, R1
Azzalis, LA1
Mattei, R1
Junqueira, VB1
Carlini, EA1
Araki, T1
Kato, H1
Shuto, K1
Fujiwara, T1
Itoyama, Y1
Thomas, WS1
Neal-Beliveau, BS1
Joyce, JN3
Guthrie, KM1
Pullara, JM1
Marshall, JF1
Leon, M1
Neal, BS1
Rao, PA1
Molinoff, PB1
Battaglia, G1
Norman, AB1
Creese, I1

Other Studies

9 other studies available for mazindol and Aging

ArticleYear
Chronic nicotine intake decelerates aging of nigrostriatal dopaminergic neurons.
    Life sciences, 1994, Volume: 54, Issue:16

    Topics: Aging; Animals; Apomorphine; Benzazepines; Binding Sites; Body Weight; Cellular Senescence; Corpus S

1994
Antioxidant defense in rat brain after chronic treatment with anorectic drugs.
    Toxicology letters, 1995, Nov-15, Volume: 81, Issue:2-3

    Topics: Aging; Animals; Antioxidants; Appetite Depressants; Brain; Catalase; Dopamine Uptake Inhibitors; Glu

1995
Effect of aging on dopaminergic receptors and uptake sites in the rat brain studied by receptor autoradiography.
    Journal of the neurological sciences, 1997, May-29, Volume: 148, Issue:2

    Topics: Aging; Animals; Autoradiography; Benzamides; Benzazepines; Brain Chemistry; Dopamine Antagonists; Do

1997
There is a limited critical period for dopamine's effects on D1 receptor expression in the developing rat neostriatum.
    Brain research. Developmental brain research, 1998, Nov-01, Volume: 111, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Benzazepines; Carrier Proteins; Corpus Striatum; Dopamine; Dopamin

1998
Olfactory deprivation increases dopamine D2 receptor density in the rat olfactory bulb.
    Synapse (New York, N.Y.), 1991, Volume: 8, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Autoradiography; Benzazepines; Catecholamines; Functional Laterali

1991
Dopamine D1 receptor behavioral responsitivity following selective lesions of the striatal patch compartment during development.
    Brain research. Developmental brain research, 1991, Jun-21, Volume: 60, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Analysis of Variance; Animals; An

1991
Ontogeny of dopamine D1 and D2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study.
    Brain research. Developmental brain research, 1991, Jun-21, Volume: 60, Issue:2

    Topics: Aging; Animals; Autoradiography; Basal Ganglia; Benzamides; Benzazepines; Dopamine Antagonists; Fema

1991
Relationship between [3H]mazindol binding to dopamine uptake sites and [3H]dopamine uptake in rat striatum during aging.
    Journal of neurochemistry, 1991, Volume: 56, Issue:2

    Topics: Aging; Animals; Carrier Proteins; Cell Membrane; Corpus Striatum; Dopamine; Dopamine Antagonists; Do

1991
Age-related differential recovery rates of rat striatal D-1 dopamine receptors following irreversible inactivation.
    European journal of pharmacology, 1988, Jan-19, Volume: 145, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aging; Animals; Flupenthixol; Male; Mazindol; Quinolines; Rats; Rats,

1988