mazindol has been researched along with Addison Disease in 1 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Addison Disease: An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of mazindol, an anorexiant, on the secretion of anterior pituitary and adrenocortical hormones were examined in healthy male volunteers and in patients with Addison's disease." | 3.67 | Acute effects of mazindol on the secretion of ACTH, beta-lipotropin, beta-endorphin and cortisol in man. ( Ibayashi, H; Kato, K; Okajima, T; Sekiya, K, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sekiya, K | 1 |
| Okajima, T | 1 |
| Kato, K | 1 |
| Ibayashi, H | 1 |
1 other study available for mazindol and Addison Disease
| Article | Year |
|---|---|
Acute effects of mazindol on the secretion of ACTH, beta-lipotropin, beta-endorphin and cortisol in man.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Endorphins; Hu | 1984 |