mazindol has been researched along with Ache in 5 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Synthesis and testing of a series of cyclohexanol ethylpiperazines identified ( S)-(-)- 17i (WAY-256805), a potent norepinephrine reuptake inhibitor (IC 50 = 82 nM, K i = 50 nM) that exhibited excellent selectivity over both the serotonin and dopamine transporters and was efficacious in animal models of depression, pain, and thermoregulatory dysfunction." | 3.74 | Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors. ( Belardi, JK; Bray, JA; Burroughs, KD; Cohn, ST; Cosmi, SA; Deecher, DC; Gavrin, LK; Ho, DM; Johnston, GH; Koury, EJ; Leiter, J; Leventhal, L; Mahaney, PE; Mugford, CA; Platt, B; Rosenzweig-Lipson, SJ; Sabatucci, JP; Santilli, AA; Smith, VA; Stack, GP; Trybulski, EJ; Vu, TA; Ye, F; Zhang, Y, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahaney, PE | 1 |
| Gavrin, LK | 1 |
| Trybulski, EJ | 1 |
| Stack, GP | 1 |
| Vu, TA | 1 |
| Cohn, ST | 1 |
| Ye, F | 1 |
| Belardi, JK | 1 |
| Santilli, AA | 1 |
| Sabatucci, JP | 1 |
| Leiter, J | 1 |
| Johnston, GH | 1 |
| Bray, JA | 1 |
| Burroughs, KD | 1 |
| Cosmi, SA | 1 |
| Leventhal, L | 1 |
| Koury, EJ | 1 |
| Zhang, Y | 1 |
| Mugford, CA | 1 |
| Ho, DM | 1 |
| Rosenzweig-Lipson, SJ | 1 |
| Platt, B | 1 |
| Smith, VA | 1 |
| Deecher, DC | 1 |
| Vendruscolo, LF | 1 |
| Takahashi, RN | 1 |
| McEwen, J | 1 |
| Meyboom, RH | 1 |
| Toda, Y | 1 |
| Kobayashi, T | 1 |
| Zahorska-Markiewicz, B | 1 |
| Kucio, C | 1 |
1 trial available for mazindol and Ache
| Article | Year |
|---|---|
The usefulness of walking for preventing sarcopenia in dieting postmenopausal women complaining of knee pain.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Appetite Depressants; Body Composition; Combined Moda | 2000 |
4 other studies available for mazindol and Ache
| Article | Year |
|---|---|
Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors.
Topics: Animals; Cell Line; Cyclohexanols; Ethylamines; Female; Humans; Male; Mice; Models, Molecular; Molec | 2008 |
Synergistic interaction between mazindol, an anorectic drug, and swim-stress on analgesic responses in the formalin test in mice.
Topics: Animals; Brain; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationsh | 2004 |
Testicular pain caused by mazindol.
Topics: Adult; Humans; Indoles; Male; Mazindol; Middle Aged; Pain; Testicular Diseases | 1983 |
[Effect of eating and mazindol on the pain threshold in obese and lean persons].
Topics: Adult; Eating; Female; Humans; Indoles; Mazindol; Obesity; Pain; Pain Measurement; Sensory Threshold | 1985 |