masoprocol and Edema
masoprocol has been researched along with Edema in 26 studies
nordihydroguaretic acid: antioxidant compound found in the creosote bush (Larrea tridentata)
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The compound 14d induced equipotent inhibition against rat paw edema, which is very close to the effect produced by the commonly used standard, namely indomethacin (47%)." | 3.77 | Synthesis, in silico docking experiments of new 2-pyrrolidinone derivatives and study of their anti-inflammatory activity. ( Georgikopoulou, K; Hadjipavlou-Litina, D; Mavromoustakos, T; Michas, G; Moutevelis-Minakakis, P; Neophytou, N; Papavassilopoulou, E; Ragoussi, ME; Zoumpoulakis, P, 2011) |
| " Acitretin and its analogs 5-7, 10, 11 and 15 inhibited lipid peroxidation more strongly than trolox whereas acitretin and analog 4 were in vivo more potent anti-inflammatory agents on rat paw oedema induced by Carrageenan than indomethacin." | 3.76 | Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer. ( Hadjipavlou-Litina, D; Krokidis, M; Magoulas, GE; Papaioannou, D, 2010) |
| " africana was examined for topical antiinflammatory activity and proved to be active against arachidonic acid (AA) acute edema, 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced chronic inflammation, and oxazolone delayed-type hypersensitivity in mice." | 3.69 | Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark. ( Cerdá, M; Cuéllar, MJ; Giner, RM; Hostettmann, K; Just, MJ; Máñez, S; Recio, MC; Ríos, JL, 1997) |
| "2 microM) and show excellent antiinflammatory potency in the mouse arachidonic acid ear edema model." | 3.68 | 2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity. ( Batt, DG; Galbraith, W; Harris, RR; Maynard, GD; Petraitis, JJ; Shaw, JE, 1990) |
| " Finally, these active inhibitors of 5-lipoxygenase inhibited arachidonic acid-induced mouse ear edema more than phenidone." | 3.68 | 3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors. ( Izumi, A; Matsumoto, H; Miki, T; Nihro, Y; Satoh, T; Sogawa, S; Ueda, H, 1993) |
Research
Studies (26)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Batt, DG | 1 |
| Maynard, GD | 1 |
| Petraitis, JJ | 1 |
| Shaw, JE | 1 |
| Galbraith, W | 1 |
| Harris, RR | 1 |
| Malleron, JL | 1 |
| Roussel, G | 1 |
| Gueremy, G | 1 |
| Ponsinet, G | 1 |
| Robin, JL | 1 |
| Terlain, B | 1 |
| Tissieres, JM | 1 |
| Sogawa, S | 1 |
| Nihro, Y | 1 |
| Ueda, H | 1 |
| Izumi, A | 1 |
| Miki, T | 1 |
| Matsumoto, H | 1 |
| Satoh, T | 1 |
| Cuéllar, MJ | 1 |
| Giner, RM | 1 |
| Recio, MC | 1 |
| Just, MJ | 1 |
| Máñez, S | 1 |
| Cerdá, M | 1 |
| Hostettmann, K | 1 |
| Ríos, JL | 1 |
| Sridhar, C | 1 |
| Subbaraju, GV | 1 |
| Venkateswarlu, Y | 1 |
| Venugopal, RT | 1 |
| Kontogiorgis, CA | 1 |
| Hadjipavlou-Litina, DJ | 5 |
| Rao, PN | 1 |
| Chen, QH | 1 |
| Knaus, EE | 3 |
| Detsi, A | 2 |
| Bouloumbasi, D | 1 |
| Prousis, KC | 1 |
| Koufaki, M | 2 |
| Athanasellis, G | 1 |
| Melagraki, G | 2 |
| Afantitis, A | 2 |
| Igglessi-Markopoulou, O | 2 |
| Kontogiorgis, C | 3 |
| Pontiki, E | 3 |
| Hadjipavlou-Litina, D | 11 |
| Burguete, A | 1 |
| Villar, R | 1 |
| Vicente, E | 1 |
| Solano, B | 1 |
| Ancizu, S | 1 |
| Pérez-Silanes, S | 1 |
| Aldana, I | 1 |
| Monge, A | 1 |
| Chowdhury, MA | 2 |
| Chen, H | 1 |
| Abdellatif, KR | 2 |
| Dong, Y | 2 |
| Petruk, KC | 1 |
| Symeonidis, T | 2 |
| Chamilos, M | 1 |
| Kallitsakis, M | 1 |
| Litinas, KE | 3 |
| Fylaktakidou, KC | 2 |
| Magoulas, GE | 3 |
| Krokidis, M | 1 |
| Papaioannou, D | 3 |
| Huang, Z | 1 |
| Yu, G | 1 |
| Velázquez, CA | 1 |
| Ispikoudi, M | 1 |
| Amvrazis, M | 1 |
| Koumbis, AE | 1 |
| Bariamis, SE | 2 |
| Drainas, D | 1 |
| Avgoustakis, K | 1 |
| Moutevelis-Minakakis, P | 1 |
| Papavassilopoulou, E | 1 |
| Michas, G | 1 |
| Georgikopoulou, K | 1 |
| Ragoussi, ME | 1 |
| Neophytou, N | 1 |
| Zoumpoulakis, P | 1 |
| Mavromoustakos, T | 1 |
| Tan, CM | 1 |
| Chen, GS | 1 |
| Chen, CS | 1 |
| Chang, PT | 1 |
| Chern, JW | 1 |
| Eleftheriou, P | 1 |
| Geronikaki, A | 2 |
| Vicini, P | 1 |
| Filz, O | 1 |
| Filimonov, D | 1 |
| Poroikov, V | 1 |
| Chaudhaery, SS | 1 |
| Roy, KK | 1 |
| Saxena, AK | 1 |
| Chioua, M | 1 |
| Sucunza, D | 1 |
| Soriano, E | 1 |
| Alcázar, A | 1 |
| Ayuso, I | 1 |
| Oset-Gasque, MJ | 1 |
| González, MP | 1 |
| Monjas, L | 1 |
| Rodríguez-Franco, MI | 1 |
| Marco-Contelles, J | 2 |
| Samadi, A | 2 |
| Apostolidis, I | 1 |
| Liaras, K | 1 |
| Gavalas, A | 1 |
| Soković, M | 1 |
| Glamočlija, J | 1 |
| Ćirić, A | 1 |
| Unzeta, M | 1 |
| Theodosis-Nobelos, P | 1 |
| Kourti, M | 1 |
| Tziona, P | 1 |
| Kourounakis, PN | 1 |
| Rekka, EA | 1 |
| Grafanaki, K | 1 |
| Tsegenidis, T | 1 |
| Athanassopoulos, CM | 1 |
| Maroulis, G | 1 |
Other Studies
26 other studies available for masoprocol and Edema
| Article | Year |
|---|---|
2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemis | 1990 |
Penta- and hexadienoic acid derivatives: a novel series of 5-lipoxygenase inhibitors.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Assay; Dose-Re | 1990 |
3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Line; Chalcone; C | 1993 |
Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Edema; Enzyme Inhibi | 1997 |
New acylated iridoid glucosides from Vitex altissima.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Edema; Enzyme Inhibitors; Free | 2004 |
Synthesis and antiinflammatory activity of coumarin derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Coumarins; C | 2005 |
Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Topics: Administration, Oral; Alkynes; Analgesics; Animals; Arachidonate 15-Lipoxygenase; Carrageenan; Cyclo | 2006 |
Design and synthesis of novel quinolinone-3-aminoamides and their alpha-lipoic acid adducts as antioxidant and anti-inflammatory agents.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biphenyl Compounds; Carragee | 2007 |
Synthesis and pharmacochemical evaluation of novel aryl-acetic acid inhibitors of lipoxygenase, antioxidants, and anti-inflammatory agents.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Edema; Free Radicals; Hin | 2007 |
Synthesis and anti-inflammatory/antioxidant activities of some new ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives and of their 4,5-dihydro-(1H)-pyrazole analogues.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Edema; Pyrazoles; Quinoxalines; Rats | 2007 |
Synthesis and biological evaluation of 1-(benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene regioisomers: a novel class of 5-lipoxygenase inhibitors.
Topics: Acetylene; Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Chemistry, Pharmaceutical | 2008 |
Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors.
Topics: Animals; Antioxidants; Biphenyl Compounds; Combinatorial Chemistry Techniques; Coumarins; Edema; Lip | 2009 |
Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Coumarins; Edema; Female; Glycine max; Lipoxygenase | 2009 |
Synthesis and anti-inflammatory evaluation of novel angularly or linearly fused coumarins.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Coumarins; Edema; Female; Male; Molecular Structure | 2009 |
Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer.
Topics: Acitretin; Amides; Animals; Antioxidants; Edema; Electrons; Esters; Female; Glycine max; Heterocycli | 2010 |
Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclooxygenase 2 I | 2010 |
Convenient synthesis and biological profile of 5-amino-substituted 1,2,4-oxadiazole derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Edema; Female | 2010 |
Does conjugation of antioxidants improve their antioxidative/anti-inflammatory potential?
Topics: Acitretin; Animals; Anti-Inflammatory Agents; Antioxidants; Edema; Levodopa; Lipid Peroxidation; Rat | 2010 |
Synthesis, in silico docking experiments of new 2-pyrrolidinone derivatives and study of their anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Catalytic Domain; Computer Simulation; Edema; Imid | 2011 |
Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclooxygenase 2 I | 2011 |
Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygen | 2012 |
Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood-Brain Barrier; Cell Hypoxia; C | 2012 |
Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cycloo | 2013 |
Analysis of the antioxidant properties of differently substituted 2- and 3-indolyl carbohydrazides and related derivatives.
Topics: Alzheimer Disease; Animals; Antioxidants; Biocatalysis; Biphenyl Compounds; Carrageenan; Edema; Fema | 2013 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine ma | 2015 |
Synthesis and biological evaluation of new C-10 substituted dithranol pleiotropic hybrids.
Topics: Amides; Animals; Anthralin; Anti-Inflammatory Agents; Antioxidants; Binding Sites; Carrageenan; Cell | 2015 |