mart-1-antigen and Cystadenocarcinoma--Serous

mart-1-antigen has been researched along with Cystadenocarcinoma--Serous* in 2 studies

Other Studies

2 other study(ies) available for mart-1-antigen and Cystadenocarcinoma--Serous

ArticleYear
Melan A (A103) is not a marker of mesothelioma.
    Applied immunohistochemistry & molecular morphology : AIMM, 2013, Volume: 21, Issue:2

    Although a large number of immunohistochemical markers have been proven to be valuable in the differential diagnosis between epithelioid mesotheliomas and metastatic carcinomas involving the serosal membrane, no single antibody has been found that is absolutely sensitive and/or specific in making this distinction. A recent study reported melan A positivity in all 12 of the epithelioid mesotheliomas stained with a melan A antibody (clone A103). To fully determine the practical value of this antibody for assisting in the differential diagnosis of mesotheliomas, we investigated the expression of melan A (A103) in 40 mesotheliomas (27 epithelioid, 6 sarcomatoid, and 7 biphasic), 10 lung adenocarcinomas, and 10 serous carcinomas of the ovary. None of the mesotheliomas, lung adenocarcinomas, or serous carcinomas of the ovary were melan A (A103) positive. Similar staining results were observed in the 20 mesotheliomas immunostained in another institution using the same antibody clone from a different commercial source. On the basis of these results, it is concluded that in contrast to the initial report, melan A (A103) is not expressed in mesotheliomas and therefore, immunostaining with this antibody has no utility in the diagnosis of mesothelioma. The possible cause of the discrepancies between the results obtained in the present investigation and those of the initial study is discussed.

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Biomarkers, Tumor; Cystadenocarcinoma, Serous; Diagnosis, Differential; Female; Gene Expression; Humans; Immunohistochemistry; Lung Neoplasms; MART-1 Antigen; Mesothelioma; Ovarian Neoplasms; Pleural Neoplasms; Retrospective Studies

2013
[Application of immunohistochemistry and its limitations in diagnosis of ovarian sex cord-stromal tumor].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2010, Volume: 39, Issue:1

    Topics: 12E7 Antigen; Antigens, CD; Calbindin 2; Carcinoma, Endometrioid; CD56 Antigen; Cell Adhesion Molecules; Cystadenocarcinoma, Serous; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Inhibins; MART-1 Antigen; Neprilysin; Ovarian Neoplasms; S100 Calcium Binding Protein G; Sertoli-Leydig Cell Tumor; Sex Cord-Gonadal Stromal Tumors; Steroidogenic Factor 1; WT1 Proteins

2010