Page last updated: 2024-09-03

marimastat and Breast Cancer

marimastat has been researched along with Breast Cancer in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's7 (58.33)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, X; He, W; Lin, C; Lv, Y; Qin, C; Xin, X; Xu, C; Yang, L; Yang, X; Yin, L; Zhang, L; Zhao, X1
He, W; Xiao, Q; Yin, L; Yuan, Y; Zhu, X1
Haage, A; Schneider, IC1
Adam, MJ; auf dem Keller, U; Bellac, CL; BĂ©nard, F; Dedhar, S; Harwig, C; Kappelhoff, R; Lange, PF; Li, Y; Lou, Y; Overall, CM; Perrin, DM; Ruth, TJ; Ting, R1
Cobleigh, M; Gradishar, W; Miller, KD; Rasmussen, H; Robert, N; Schuchter, L; Sledge, GW; Sparano, JA1
Moses, MA; Pories, SE; Roy, R; Wewer, UM; Zurakowski, D1
Bernardo, P; Davidson, NE; Gradishar, WJ; Ingle, JN; Sparano, JA; Stephenson, P; Zucker, S1
Davidson, NE; Gradishar, WJ; Ingle, JN; Sparano, JA; Wang, M; Zucker, S1
McCann, PP; Rasmussen, HS1
Brown, PD1
Fletcher, L1
Balduyck, M; Dacquembronne, E; Dejonghe, MJ; Duhem, T; Gouyer, V; Grard, G; Hemon, B; Huet, G; Lebrun, A; Lemaire, R; Lemaire, V; Thiebaut, C; Zerimech, F1

Reviews

1 review(s) available for marimastat and Breast Cancer

ArticleYear
Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat.
    Pharmacology & therapeutics, 1997, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Enzyme Inhibitors; Female; Hemangioma; Humans; Hydroxamic Acids; Melanoma; Metalloendopeptidases; Mice; Ovarian Neoplasms; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Skin Neoplasms; Thiophenes

1997

Trials

3 trial(s) available for marimastat and Breast Cancer

ArticleYear
A randomized phase II pilot trial of adjuvant marimastat in patients with early-stage breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Matrix Metalloproteinase Inhibitors; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pilot Projects; Safety; Survival Rate; Treatment Outcome

2002
Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Dec-01, Volume: 22, Issue:23

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hydroxamic Acids; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Probability; Proportional Hazards Models; Reference Values; Risk Assessment; Survival Analysis; Treatment Outcome

2004
Plasma matrix metalloproteinases 7 and 9 in patients with metastatic breast cancer treated with marimastat or placebo: Eastern Cooperative Oncology Group trial E2196.
    Clinical breast cancer, 2006, Volume: 6, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxamic Acids; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; Middle Aged; Placebos; Predictive Value of Tests; Prognosis

2006

Other Studies

8 other study(ies) available for marimastat and Breast Cancer

ArticleYear
Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells.
    ACS nano, 2018, 02-27, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Drug Delivery Systems; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hydroxamic Acids; Liposomes; MCF-7 Cells; Mice, Inbred BALB C; Paclitaxel; Prodrugs; Tumor Microenvironment

2018
A drug-delivering-drug strategy for combined treatment of metastatic breast cancer.
    Nanomedicine : nanotechnology, biology, and medicine, 2018, Volume: 14, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caseins; Cell Proliferation; Drug Combinations; Drug Delivery Systems; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Lung Neoplasms; Matrix Metalloproteinases; Mice; Nanoparticles; Paclitaxel; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Cellular contractility and extracellular matrix stiffness regulate matrix metalloproteinase activity in pancreatic cancer cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:8

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Shape; Collagen; Elasticity; Extracellular Matrix; Gels; Heparan Sulfate Proteoglycans; Heparin Lyase; Humans; Hydroxamic Acids; Matrix Metalloproteinases; Neoplasm Invasiveness; Neoplasm Proteins; Pancreatic Neoplasms; Recombinant Proteins

2014
Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.
    Cancer research, 2010, Oct-01, Volume: 70, Issue:19

    Topics: Animals; Borates; Breast Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Female; Fluorine Radioisotopes; Humans; Hydroxamic Acids; Isoenzymes; Isotope Labeling; Mammary Neoplasms, Experimental; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Positron-Emission Tomography; Radiopharmaceuticals

2010
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: ADAM Proteins; ADAM12 Protein; Adult; Aged; Amino Acid Sequence; Animals; Blotting, Western; Breast Neoplasms; Caseins; Catalysis; Chelating Agents; Chromatography, Affinity; Chromatography, Ion Exchange; Collagen Type I; Collagen Type IV; COS Cells; Databases as Topic; Densitometry; Disease Progression; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Extracellular Matrix; Female; Fibronectins; Gelatin; Humans; Hydroxamic Acids; Immunoblotting; Membrane Proteins; Metalloendopeptidases; Middle Aged; Molecular Sequence Data; Neoplasm Metastasis; Peptides; Phenanthrolines; Plasmids; Recombinant Proteins; Sensitivity and Specificity; Sepharose; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Ultracentrifugation; Zinc

2004
Ongoing trials with matrix metalloproteinase inhibitors.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:9

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Breast Neoplasms; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Enzyme Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Organic Chemicals; Phenylbutyrates

2000
MMPI demise spotlights target choice.
    Nature biotechnology, 2000, Volume: 18, Issue:11

    Topics: Breast Neoplasms; Clinical Trials as Topic; Drug Industry; Female; Humans; Hydroxamic Acids; Matrix Metalloproteinase Inhibitors

2000
Specific expression of matrix metalloproteinases 1, 3, 9 and 13 associated with invasiveness of breast cancer cells in vitro.
    Clinical & experimental metastasis, 2000, Volume: 18, Issue:2

    Topics: Base Sequence; Basement Membrane; Breast Neoplasms; Collagen; DNA Primers; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Hydroxamic Acids; Laminin; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured

2000