maraviroc and Acquired-Immunodeficiency-Syndrome

maraviroc has been researched along with Acquired-Immunodeficiency-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for maraviroc and Acquired-Immunodeficiency-Syndrome

Article	Year
1-Amido-1-phenyl-3-piperidinylbutanes - CCR5 antagonists for the treatment of HIV. Part 1. Bioorganic & medicinal chemistry letters, 2009, Feb-15, Volume: 19, Issue:4 The development of a new class of CCR5 antagonist replacing the tropane core of maraviroc by piperidine with a branched N-substituent is described. Compound 15h shows good whole cell antiviral activity together with microsomal stability and only weak activity at the hERG ion channel. Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Butanes; CCR5 Receptor Antagonists; Combinatorial Chemistry Techniques; Ether-A-Go-Go Potassium Channels; HIV; HIV Infections; Humans; Molecular Structure; Piperidines; Structure-Activity Relationship; Tropanes	2009

Article

Year

1-Amido-1-phenyl-3-piperidinylbutanes - CCR5 antagonists for the treatment of HIV. Part 1.

Bioorganic & medicinal chemistry letters, 2009, Feb-15, Volume: 19, Issue:4

The development of a new class of CCR5 antagonist replacing the tropane core of maraviroc by piperidine with a branched N-substituent is described. Compound 15h shows good whole cell antiviral activity together with microsomal stability and only weak activity at the hERG ion channel.

Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Butanes; CCR5 Receptor Antagonists; Combinatorial Chemistry Techniques; Ether-A-Go-Go Potassium Channels; HIV; HIV Infections; Humans; Molecular Structure; Piperidines; Structure-Activity Relationship; Tropanes

2009