maprotiline has been researched along with Low Back Pain in 1 studies
Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
Low Back Pain: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To understand the relative efficacy of noradrenergic and serotonergic antidepressants as analgesics in chronic back pain without depression, we conducted a randomized, double-blind, placebo-control head-to-head comparison of maprotiline (a norepinephrine reuptake blocker) and paroxetine (a serotonin reuptake blocker) in 103 patients with chronic low back pain." | 5.09 | Effects of noradrenergic and serotonergic antidepressants on chronic low back pain intensity. ( Abramson, I; Atkinson, JH; Epping-Jordan, JE; Garfin, SR; Grant, I; Patterson, TL; Pruitt, SD; Slater, MA; Wahlgren, DR; Williams, RA; Zisook, S, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atkinson, JH | 1 |
| Slater, MA | 1 |
| Wahlgren, DR | 1 |
| Williams, RA | 1 |
| Zisook, S | 1 |
| Pruitt, SD | 1 |
| Epping-Jordan, JE | 1 |
| Patterson, TL | 1 |
| Grant, I | 1 |
| Abramson, I | 1 |
| Garfin, SR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cipralex in Treatment of Depressive Symptoms and Chronic Back Pain[NCT00227292] | Phase 4 | 0 participants (Actual) | Interventional | 2007-11-30 | Withdrawn (stopped due to Mutual agreement between Sponsor and Investigator.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for maprotiline and Low Back Pain
| Article | Year |
|---|---|
Effects of noradrenergic and serotonergic antidepressants on chronic low back pain intensity.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Chronic Disease; Diphenhydramine; Double-Blind Method; Hu | 1999 |