maprotiline has been researched along with Disease Models, Animal in 13 studies
Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response studies using two classes of anxiolytics (chlordiazepoxide: 2." | 1.35 | Modelling the anxiety-depression continuum in chicks. ( Acevedo, EO; Huang, CJ; Sufka, KJ; Warnick, JE, 2009) |
| "Amitriptyline was studied in greater detail and caused a dose-related (0." | 1.30 | Acute lung failure induced by tricyclic antidepressants. ( Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A, 1997) |
| "On the average, seizures were observed at 40 mg/kg and were seen after desmethylimipramine (50 mg/kg), mianserin (30 mg/kg), amitriptyline (20 mg/kg), imipramine (40 mg/kg), maprotiline (40 mg/kg), and zimelidine (50 mg/kg)." | 1.27 | Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. ( Bradford, D; Krijzer, F; Snelder, M, 1984) |
| " Chronic administration of imipramine-HCl (1 and 5 mg/kg, i." | 1.27 | Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice. ( Kameyama, T; Nagasaka, M; Yamada, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Chen, W | 1 |
| Liu, P | 1 |
| Liu, D | 1 |
| Huang, H | 1 |
| Feng, X | 1 |
| Fang, F | 1 |
| Li, L | 1 |
| Wu, J | 1 |
| Liu, L | 1 |
| Solow-Cordero, DE | 1 |
| Hu, Y | 1 |
| Dean, SN | 1 |
| van Hoek, ML | 1 |
| Ide, S | 1 |
| Satoyoshi, H | 1 |
| Minami, M | 1 |
| Satoh, M | 1 |
| Krügel, U | 1 |
| Straub, I | 1 |
| Beckmann, H | 1 |
| Schaefer, M | 1 |
| Warnick, JE | 1 |
| Huang, CJ | 1 |
| Acevedo, EO | 1 |
| Sufka, KJ | 1 |
| Pettersen, VL | 1 |
| Zapata-Sudo, G | 1 |
| Raimundo, JM | 1 |
| Trachez, MM | 1 |
| Sudo, RT | 1 |
| Krijzer, F | 1 |
| Snelder, M | 1 |
| Bradford, D | 1 |
| Dahlin, KL | 1 |
| Lâstbom, L | 1 |
| Blomgren, B | 1 |
| Ryrfeldt, A | 1 |
| Noguchi, S | 1 |
| Fukuda, Y | 1 |
| Inukai, T | 1 |
| Kaltwasser, MT | 1 |
| Kameyama, T | 1 |
| Nagasaka, M | 1 |
| Yamada, K | 1 |
13 other studies available for maprotiline and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Maprotiline restores ER homeostasis and rescues neurodegeneration via Histamine Receptor H1 inhibition in retinal ganglion cells.
Topics: Animals; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Homeostasis; M | 2022 |
Screen of FDA-approved drug library identifies maprotiline, an antibiofilm and antivirulence compound with QseC sensor-kinase dependent activity in Francisella novicida.
Topics: Animals; Biofilms; Disease Models, Animal; Female; Francisella; Gene Expression Regulation, Bacteria | 2015 |
Amelioration of the reduced antinociceptive effect of morphine in the unpredictable chronic mild stress model mice by noradrenalin but not serotonin reuptake inhibitors.
Topics: Analgesics; Animals; Chronic Disease; Citalopram; Disease Models, Animal; Male; Maprotiline; Mice, I | 2015 |
Primidone inhibits TRPM3 and attenuates thermal nociception in vivo.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; | 2017 |
Modelling the anxiety-depression continuum in chicks.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Chickens; Chlordiaze | 2009 |
The synergistic interaction between morphine and maprotiline after intrathecal injection in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics, Opioid; Anima | 2009 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Re | 1984 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose- | 1997 |
Possible contributory role of the central histaminergic system in the forced swimming model.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Central Nervous System; Depressive Disorder; Diseas | 1992 |
Acoustic startle induced ultrasonic vocalization in the rat: a novel animal model of anxiety?
Topics: Animals; Anti-Anxiety Agents; Anxiety; Appetite Depressants; Arousal; Carbolines; Diazepam; Disease | 1991 |
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhy | 1985 |