maprotiline has been researched along with Constipation in 4 studies
Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maprotiline hydrochloride tablets were given to 266 patients with either a dysthymic disorder or a major depressive disorder." | 5.05 | Multicenter evaluation of maprotiline hydrochloride for treatment of depression. ( , 1984) |
| " A significant positive correlation was obtained between dosage and blood levels of maprotiline and doxepin, but there was no correlation between blood levels and clinical response." | 2.65 | Therapeutic superiority of maprotiline versus doxepin in geriatric depression. ( Ahles, S; DeMet, E; Gwirtsman, HE; Halaris, A; Hill, MA, 1983) |
| " The authors suggest that Ludiomil at a maximal dosage of 150 mg/d can be considered a relatively safe and effective antidepressant." | 1.28 | Maprotiline (Ludiomil) treatment of mental depression--a clinical report of 65 cases. ( Li, SW; Yan, HQ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gwirtsman, HE | 1 |
| Ahles, S | 1 |
| Halaris, A | 1 |
| DeMet, E | 1 |
| Hill, MA | 1 |
| Leroi, AM | 1 |
| Lalaude, O | 1 |
| Antonietti, M | 1 |
| Touchais, JY | 1 |
| Ducrotte, P | 1 |
| Menard, JF | 1 |
| Denis, P | 1 |
| Li, SW | 1 |
| Yan, HQ | 1 |
2 trials available for maprotiline and Constipation
| Article | Year |
|---|---|
Therapeutic superiority of maprotiline versus doxepin in geriatric depression.
Topics: Anthracenes; Clinical Trials as Topic; Constipation; Depressive Disorder; Dizziness; Double-Blind Me | 1983 |
Multicenter evaluation of maprotiline hydrochloride for treatment of depression.
Topics: Adolescent; Adult; Aged; Anthracenes; Anxiety; Clinical Trials as Topic; Constipation; Depressive Di | 1984 |
2 other studies available for maprotiline and Constipation
| Article | Year |
|---|---|
Prolonged stationary colonic motility recording in seven patients with severe constipation secondary to antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Cathartics; Cholinergic Antagonists; | 2000 |
Maprotiline (Ludiomil) treatment of mental depression--a clinical report of 65 cases.
Topics: Adolescent; Adult; Aged; Anthracenes; Constipation; Depressive Disorder; Female; Humans; Male; Mapro | 1989 |