maprotiline has been researched along with Chronic Disease in 10 studies
Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A group of 25 patients treated with maprotiline was studied to test the question of second-generation antidepressant effectiveness in chronic pain." | 9.05 | Maprotiline in pain-depression. ( Lindsay, PG; Olsen, RB, 1985) |
| "To understand the relative efficacy of noradrenergic and serotonergic antidepressants as analgesics in chronic back pain without depression, we conducted a randomized, double-blind, placebo-control head-to-head comparison of maprotiline (a norepinephrine reuptake blocker) and paroxetine (a serotonin reuptake blocker) in 103 patients with chronic low back pain." | 5.09 | Effects of noradrenergic and serotonergic antidepressants on chronic low back pain intensity. ( Abramson, I; Atkinson, JH; Epping-Jordan, JE; Garfin, SR; Grant, I; Patterson, TL; Pruitt, SD; Slater, MA; Wahlgren, DR; Williams, RA; Zisook, S, 1999) |
| "A group of 25 patients treated with maprotiline was studied to test the question of second-generation antidepressant effectiveness in chronic pain." | 5.05 | Maprotiline in pain-depression. ( Lindsay, PG; Olsen, RB, 1985) |
| "There have been reports that tricyclic antidepressants, such as clomipramine (Anafranil), alleviate some forms of chronic pain in man." | 3.65 | Antidepressants and pain: a review of the pharmacological data supporting the use of certain tricyclics in chronic pain. ( Lee, R; Spencer, PS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ide, S | 1 |
| Satoyoshi, H | 1 |
| Minami, M | 1 |
| Satoh, M | 1 |
| Yalcin, I | 1 |
| Belzung, C | 1 |
| Surget, A | 1 |
| Ivkovic, N | 1 |
| Mladenovic, I | 1 |
| Petkoci, S | 1 |
| Stojic, D | 1 |
| Atkinson, JH | 1 |
| Slater, MA | 1 |
| Wahlgren, DR | 1 |
| Williams, RA | 1 |
| Zisook, S | 1 |
| Pruitt, SD | 1 |
| Epping-Jordan, JE | 1 |
| Patterson, TL | 1 |
| Grant, I | 1 |
| Abramson, I | 1 |
| Garfin, SR | 1 |
| Lee, R | 1 |
| Spencer, PS | 1 |
| Nakamura, S | 1 |
| Jegede, RO | 1 |
| Baiyewu, O | 1 |
| Yamagami, S | 1 |
| Soejima, K | 1 |
| Lindsay, PG | 1 |
| Olsen, RB | 1 |
| Fogelholm, R | 1 |
| Murros, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cipralex in Treatment of Depressive Symptoms and Chronic Back Pain[NCT00227292] | Phase 4 | 0 participants (Actual) | Interventional | 2007-11-30 | Withdrawn (stopped due to Mutual agreement between Sponsor and Investigator.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for maprotiline and Chronic Disease
| Article | Year |
|---|---|
Axonal sprouting of noradrenergic locus coeruleus neurons following repeated stress and antidepressant treatment.
Topics: Animals; Antidepressive Agents; Axons; Chronic Disease; Desipramine; Electroconvulsive Therapy; Elec | 1991 |
3 trials available for maprotiline and Chronic Disease
| Article | Year |
|---|---|
Effects of noradrenergic and serotonergic antidepressants on chronic low back pain intensity.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Chronic Disease; Diphenhydramine; Double-Blind Method; Hu | 1999 |
Maprotiline in pain-depression.
Topics: Adult; Aged; Anthracenes; Antidepressive Agents; Brain; Chronic Disease; Clinical Trials as Topic; D | 1985 |
Maprotiline in chronic tension headache: a double-blind cross-over study.
Topics: Adolescent; Adult; Anthracenes; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Fema | 1985 |
6 other studies available for maprotiline and Chronic Disease
| Article | Year |
|---|---|
Amelioration of the reduced antinociceptive effect of morphine in the unpredictable chronic mild stress model mice by noradrenalin but not serotonin reuptake inhibitors.
Topics: Analgesics; Animals; Chronic Disease; Citalopram; Disease Models, Animal; Male; Maprotiline; Mice, I | 2015 |
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey.
Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Antidepressive Agents, Second-Generation; | 2008 |
TMD chronic pain and masseter silent period in psychiatric patients on antidepressive therapy.
Topics: Adult; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents; Case-Control Studies; Chron | 2008 |
Antidepressants and pain: a review of the pharmacological data supporting the use of certain tricyclics in chronic pain.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Central Nervous System; Chronic Disease; Clom | 1977 |
A study of chronic neurotic illness in Nigeria.
Topics: Adult; Aged; Anxiety Disorders; Chronic Disease; Clomipramine; Drug Therapy, Combination; Female; Hu | 1989 |
Effect of maprotiline combined with conventional neuroleptics against negative symptoms of chronic schizophrenia.
Topics: Adult; Anthracenes; Antipsychotic Agents; Chronic Disease; Drug Therapy, Combination; Female; Humans | 1989 |