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maprotiline and Bipolar Disorder

maprotiline has been researched along with Bipolar Disorder in 21 studies

Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
" A controlled, double-blind comparison of maprotiline and imipramine in a group of 71 female outpatients with primary depression is presented."5.04A controlled study of a tetracyclic antidepressant--maprotiline (Ludiomil). ( Holt, NF; Kessell, A, 1975)
"276-Ba or Maprotiline in any category of depression."3.65[Clinical and electroencephalographic study of a new antidepressive agent, mono-methyl-amino-propyl-dibenzo-bicyclo-octadine hydrochloride (Ciba 34, 276 Ba)]. ( Deniker, P; Lôo, H; Oughourlian, JM; Verdeaux, G, 1975)
"The citalopram-treated patients in whom AAM developed were significantly older than those in whom it did not (about 10 years, P < 0."2.69Is selectivity for serotonin uptake associated with a reduced emergence of manic episodes in depressed patients? ( Barak, Y; Kimhi, R; Weizman, R, 2000)
" Although the results showed lithium carbonate to be superior to maprotiline in the study, it should be emphasized that the plasma levels of lithium were constantly monitored and maintained at what is considered to be its optimum concentration, whereas the maprotiline treated patients were kept on a fixed dosage regime irrespective of plasma levels."2.64A double-blind comparison of lithium carbonate and maprotiline in the prophylaxis of the affective disorders. ( Bailey, JE; Coppen, A; Gupta, RK; Montgomery, SA, 1976)
"3H-Imipramine binding was measured in freshly prepared platelet membranes from 47 drug-free major depressives and 46 healthy controls."1.283H-imipramine binding to freshly prepared platelet membranes in depression. ( Davies, SL; Hale, AS; Horton, RW; Katona, CL; Kelly, JS; Kerry, SM; Paykel, ES; Theodorou, AE, 1989)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199017 (80.95)18.7374
1990's3 (14.29)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greden, JF1
Price, HL1
Genero, N1
Feinberg, M1
Levine, S1
Soucek, K1
Barak, Y1
Kimhi, R1
Weizman, R1
Ravizza, L1
Watanabe, S1
Yokoyama, S1
Kubo, S1
Iwai, H1
Kuyama, C1
Strian, F1
Albert, W1
Klicpera, C1
Kielholz, P2
Terzani, S1
Gastpar, M1
Adams, C1
Coppen, A1
Montgomery, SA1
Gupta, RK1
Bailey, JE1
Kessell, A1
Holt, NF1
Deniker, P1
Lôo, H2
Verdeaux, G1
Oughourlian, JM1
Benazzi, F1
Mazzoli, M1
Rossi, E1
Kontsevoĭ, VA1
Kolibash, E1
Piatnitskiĭ, AN1
Korzhinkova, V1
Andrusenko, MP1
Kostrikina, IE1
Vanelle, JM1
Poirier, MF1
Benkelfat, C1
Galinowski, A1
Sechter, D1
Suzini de Luca, H1
Theodorou, AE1
Katona, CL1
Davies, SL1
Hale, AS1
Kerry, SM1
Horton, RW1
Kelly, JS1
Paykel, ES1
Svestka, J1
Náhunek, K1
Steardo, L1
Barone, P1
Monteleone, P1
Iovino, M1
Cardone, G1
Brusov, OS1
Beliaev, BS1
Katasonov, AB1
Zlobina, GP1
Factor, MI1
Lideman, RR1
Montejo-Iglesias, ML1
Ramos-Brieva, JA1
Nolen, WA1
van de Putte, JJ1
Dijken, WA1
Kamp, JS1
Blansjaar, BA1
Kramer, HJ1
Haffmans, J1
Rihmer, Z1
Arató, M1
György, S1
Révai, K1
Demeter, E1

Trials

8 trials available for maprotiline and Bipolar Disorder

ArticleYear
Is selectivity for serotonin uptake associated with a reduced emergence of manic episodes in depressed patients?
    International clinical psychopharmacology, 2000, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Bipolar Disorder; Citalopr

2000
A double-blind controlled study of clinical efficacy of maprotiline and amitriptyline in depression.
    Folia psychiatrica et neurologica japonica, 1978, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Amitriptyline; Anthracenes; Bipolar Disorde

1978
A double-blind comparison of lithium carbonate and maprotiline in the prophylaxis of the affective disorders.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 128

    Topics: Adult; Anthracenes; Bipolar Disorder; Body Weight; Clinical Trials as Topic; Consumer Behavior; Depr

1976
A controlled study of a tetracyclic antidepressant--maprotiline (Ludiomil).
    The Medical journal of Australia, 1975, Jun-21, Volume: 1, Issue:25

    Topics: Adjustment Disorders; Adult; Anthracenes; Bipolar Disorder; Body Weight; Clinical Trials as Topic; D

1975
[Comparative study of age-related effectiveness of tri- and tetracyclic antidepressants].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1991, Volume: 91, Issue:9

    Topics: Affective Disorders, Psychotic; Age Factors; Aged; Amitriptyline; Bipolar Disorder; Depressive Disor

1991
Diagnostic and therapeutic value of testing stimulation of thyroid-stimulating hormone by thyrotropin-releasing hormone in 100 depressed patients.
    Acta psychiatrica Scandinavica, 1990, Volume: 81, Issue:2

    Topics: Adult; Aged; Bipolar Disorder; Citalopram; Depressive Disorder; Female; Humans; Male; Maprotiline; M

1990
Therapeutic effect of maprotiline and chlorimipramine: controlled study.
    Neuropsychobiology, 1988, Volume: 19, Issue:1

    Topics: Adult; Anthracenes; Bipolar Disorder; Clinical Trials as Topic; Clomipramine; Depressive Disorder; F

1988
Treatment strategy in depression. I. Non-tricyclic and selective reuptake inhibitors in resistant depression: a double-blind partial crossover study on the effects of oxaprotiline and fluvoxamine.
    Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:6

    Topics: Adult; Anthracenes; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine;

1988

Other Studies

13 other studies available for maprotiline and Bipolar Disorder

ArticleYear
Facial EMG activity levels predict treatment outcome in depression.
    Psychiatry research, 1984, Volume: 13, Issue:4

    Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Electromyo

1984
[Combined chlorimipramine and maprotiline therapy in therapy-resistant depressions].
    Activitas nervosa superior, 1982, Volume: 24, Issue:2

    Topics: Adult; Anthracenes; Bipolar Disorder; Clomipramine; Depressive Disorder; Drug Therapy, Combination;

1982
[Clinical and biochemical contributions on the action of maprotiline and clomipramine in depressive states (preliminary observation)].
    Psychiatria clinica, 1979, Volume: 13, Issue:3

    Topics: Adult; Bipolar Disorder; Clomipramine; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; M

1979
Antidepressive treatment and mood swing patterns in endogenous depression.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1979, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipra

1979
[Management of treatment-resistant depression (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Feb-10, Volume: 103, Issue:6

    Topics: Administration, Oral; Antidepressive Agents; Autogenic Training; Bipolar Disorder; Clomipramine; Dep

1978
[Diagnosis and treatment of depressive states in everyday practice (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, Oct-24, Volume: 67, Issue:43

    Topics: Adjustment Disorders; Antidepressive Agents; Bipolar Disorder; Clomipramine; Family Practice; Fatigu

1978
[Clinical and electroencephalographic study of a new antidepressive agent, mono-methyl-amino-propyl-dibenzo-bicyclo-octadine hydrochloride (Ciba 34, 276 Ba)].
    L'Encephale, 1975, Volume: 1, Issue:3

    Topics: Adjustment Disorders; Adult; Aged; Anthracenes; Bipolar Disorder; Depression; Drug Evaluation; Femal

1975
Severe mania after maprotiline-induced coma.
    Pharmacopsychiatry, 1992, Volume: 25, Issue:4

    Topics: Adult; Bipolar Disorder; Coma; Female; Humans; Maprotiline

1992
3H-imipramine binding to freshly prepared platelet membranes in depression.
    Psychiatry research, 1989, Volume: 29, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Blood Platelets; Carrier Proteins; Depressive Disorder; Dexamethasone

1989
Therapeutic results in acute phases of manic depressive and schizophrenic psychoses as possible predictors of the prophylactic effect.
    Activitas nervosa superior, 1989, Volume: 31, Issue:1

    Topics: Adult; Anthracenes; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Lithium; Male; Maprotili

1989
Is the dexamethasone suppression test predictive of response to specific antidepressant treatment in major depression?
    Acta psychiatrica Scandinavica, 1987, Volume: 76, Issue:2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Clomipramine; Depressive Disord

1987
Does platelet serotonin receptor supersensitivity accompany endogenous depression?
    Biological psychiatry, 1989, Feb-15, Volume: 25, Issue:4

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Blood Platelets; Carbazoles; Depressive Disorder; Fe

1989
Dexamethasone suppression test as an aid for selection of specific antidepressant drugs in patients with endogenous depression.
    Pharmacopsychiatry, 1985, Volume: 18, Issue:5

    Topics: Adult; Aged; Amitriptyline; Anthracenes; Bipolar Disorder; Depressive Disorder; Dexamethasone; Femal

1985