maprotiline has been researched along with Arrhythmias, Cardiac in 13 studies
Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of amitriptyline and maprotiline, standard tricyclic and tetracyclic antidepressants, on intraventricular conduction, the effective refractory period (ERP), and the incidence of ventricular arrhythmias induced by programmed stimulation were studied and compared in dog hearts after myocardial infarction." | 7.68 | Comparative effects of antidepressants, amitriptyline, and maprotiline on intraventricular conduction, effective refractory period, and incidence of ventricular arrhythmias induced by programmed stimulation in dog hearts after myocardial infarction. ( Hashimoto, H; Nakashima, M; Nishimoto, M; Oohara, K; Ozaki, T, 1990) |
| "The effects of amitriptyline and maprotiline, standard tricyclic and tetracyclic antidepressants, on intraventricular conduction, the effective refractory period (ERP), and the incidence of ventricular arrhythmias induced by programmed stimulation were studied and compared in dog hearts after myocardial infarction." | 3.68 | Comparative effects of antidepressants, amitriptyline, and maprotiline on intraventricular conduction, effective refractory period, and incidence of ventricular arrhythmias induced by programmed stimulation in dog hearts after myocardial infarction. ( Hashimoto, H; Nakashima, M; Nishimoto, M; Oohara, K; Ozaki, T, 1990) |
| "The presence or absence of cardiac arrhythmias was recorded." | 2.65 | Mianserin, maprotiline and intracardiac conduction. ( Edwards, JG; Goldie, A, 1983) |
| "Severe orthostatic hypotension is more likely to develop in depressed patients with left ventricular impairment and/or in patients taking other drugs like diuretics or vasodilators." | 2.38 | Review of the cardiovascular effects of heterocyclic antidepressants. ( Glassman, AH; Preud'homme, XA, 1993) |
| "Fifteen patients were in coma grade III or IV; 17 patients were still not conscious after 24 hours in the intensive care unit." | 1.27 | Effects of self poisoning with maprotiline. ( Heath, A; Knudsen, K, 1984) |
| "Seizures were more common in the amoxapine (24." | 1.27 | Relative toxicity of cyclic antidepressants. ( Gorman, RL; Klein-Schwartz, W; Oderda, GM; Wedin, GP, 1986) |
| " In part this is due to generally exaggerated fears that primary care physicians have regarding these medications, especially the anticholinegic effects of recommended dosage levels and sudden cardiac death." | 1.27 | Update on some of the older and newer antidepressants. ( Thompson, TL, 1985) |
| " It is concluded that all four drugs show the toxic effects classically associated with tricyclic antidepressants but the relative toxicity amongst these agents varies considerably and is in the order amitriptyline greater than imipramine greater than maprotiline greater than mianserin." | 1.26 | The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo. ( Hughes, IE; Radwan, S, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knudsen, K | 1 |
| Heath, A | 1 |
| Edwards, JG | 1 |
| Goldie, A | 1 |
| Herrmann, HC | 1 |
| Kaplan, LM | 1 |
| Bierer, BE | 1 |
| Scheinin, M | 1 |
| Engblom, E | 1 |
| Salonen, JS | 1 |
| Glassman, AH | 1 |
| Preud'homme, XA | 1 |
| Raeder, EA | 1 |
| Zinsli, M | 1 |
| Burckhardt, D | 1 |
| Piccini, P | 1 |
| Pierri, A | 1 |
| Costa, PP | 1 |
| Panza, N | 1 |
| Hughes, IE | 2 |
| Radwan, S | 1 |
| Harper, B | 1 |
| Hashimoto, H | 1 |
| Nishimoto, M | 1 |
| Ozaki, T | 1 |
| Oohara, K | 1 |
| Nakashima, M | 1 |
| Wedin, GP | 1 |
| Oderda, GM | 1 |
| Klein-Schwartz, W | 1 |
| Gorman, RL | 1 |
| Colpart, E | 1 |
| Manoury, B | 1 |
| Daumal, M | 1 |
| Boutillier, C | 1 |
| Thompson, TL | 1 |
1 review available for maprotiline and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Review of the cardiovascular effects of heterocyclic antidepressants.
Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bupropion; | 1993 |
2 trials available for maprotiline and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Mianserin, maprotiline and intracardiac conduction.
Topics: Adolescent; Adult; Anthracenes; Arrhythmias, Cardiac; Depressive Disorder; Dibenzazepines; Double-Bl | 1983 |
Effect of maprotiline on cardiac arrhythmias.
Topics: Adult; Anthracenes; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Humans; Map | 1979 |
10 other studies available for maprotiline and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Effects of self poisoning with maprotiline.
Topics: Adult; Aged; Anthracenes; Arrhythmias, Cardiac; Coma; Electrocardiography; Female; Humans; Male; Map | 1984 |
Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline.
Topics: Aged; Anthracenes; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Maprotiline; Tachycard | 1983 |
[Acute maprotiline poisoning].
Topics: Adult; Anthracenes; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Male; Maprotiline; Pr | 1981 |
[Acute poisoning by tricyclic antidepressive agents].
Topics: Acute Disease; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antidepressive Agents, Tricyclic; A | 1979 |
The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo.
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Behavior | 1979 |
A comparison in rabbit isolated hearts of the dysrhythmogenic potential of amitriptyline, maprotiline and mianserin in relation to their ability to block noradrenaline uptake.
Topics: Amitriptyline; Animals; Anthracenes; Arrhythmias, Cardiac; Dibenzazepines; Drug Interactions; Female | 1977 |
Comparative effects of antidepressants, amitriptyline, and maprotiline on intraventricular conduction, effective refractory period, and incidence of ventricular arrhythmias induced by programmed stimulation in dog hearts after myocardial infarction.
Topics: Action Potentials; Amitriptyline; Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Dogs; E | 1990 |
Relative toxicity of cyclic antidepressants.
Topics: Adolescent; Adult; Aged; Amoxapine; Anthracenes; Antidepressive Agents, Tricyclic; Arrhythmias, Card | 1986 |
[Heart conduction disorders in acute maprotiline poisoning].
Topics: Adult; Anthracenes; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Maprotiline | 1986 |
Update on some of the older and newer antidepressants.
Topics: Aged; Amoxapine; Antidepressive Agents; Arrhythmias, Cardiac; Humans; Maprotiline; Parasympathetic N | 1985 |