Page last updated: 2024-10-30

maprotiline and Aggression

maprotiline has been researched along with Aggression in 8 studies

Maprotiline: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
" An analogous potentiation of clonidine-induced aggressiveness was obtained with chronic administration (the schedule as above) of levomepromazine (2 mg/kg) or thioridazine (5 mg/kg) but not of spiperone (0."5.26Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. ( Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E, 1981)
" An analogous potentiation of clonidine-induced aggressiveness was obtained with chronic administration (the schedule as above) of levomepromazine (2 mg/kg) or thioridazine (5 mg/kg) but not of spiperone (0."1.26Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. ( Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E, 1981)
"Maprotiline in particular was more efficacious than any of the other compounds in preventing or suppressing aggressiveness after chronic treatment at doses inactive upon acute administration."1.26The effects of antidepressants on aggressiveness induced by social deprivation in mice. ( Delini-Stula, A; Vassout, A, 1981)
"Maprotiline was more potent than anitriptyline and imipramine in antagonizing haloperidol-induced catalepsy as well as in suppressing muricide induced by either olfactory bulbectomy or delta-9-tetrahydrocannabinol in rats."1.25[Behavior pharmacology of maprotiline, a new antidepressant]. ( Fujiwara, M; Ibii, N; Inoue, K; Kataoka, Y; Ueki, S, 1975)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maj, J2
Rogóz, Z1
Skuza, G1
Mogilnicka, E2
Boissard, CG1
Waldmeier, PC1
Delini-Stula, A2
Klimek, V1
Kordecka-Magiera, A1
Vassout, A1
Cai, B1
Matsumoto, K1
Ohta, H1
Watanabe, H1
Pinder, RM1
Brogden, RN1
Speight, TM1
Avery, GS1
Ueki, S1
Fujiwara, M1
Inoue, K1
Kataoka, Y1
Ibii, N1
Noguchi, S1
Inukai, T1
Kuno, T1
Tanaka, C1

Reviews

1 review available for maprotiline and Aggression

ArticleYear
Maprotiline: a review of its pharmacological properties and therapeutic efficacy in mental depressive states.
    Drugs, 1977, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Aggression; Animals; Anthracenes; Antidepressive Agents; Blood Proteins; Cl

1977

Trials

1 trial available for maprotiline and Aggression

ArticleYear
Maprotiline: a review of its pharmacological properties and therapeutic efficacy in mental depressive states.
    Drugs, 1977, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Aggression; Animals; Anthracenes; Antidepressive Agents; Blood Proteins; Cl

1977

Other Studies

7 other studies available for maprotiline and Aggression

ArticleYear
(+)-Oxaprotiline but not (-)-oxaprotiline given chronically potentiates the aggressive behaviour induced by clonidine.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:3

    Topics: Aggression; Animals; Anthracenes; Antidepressive Agents; Clonidine; Drug Synergism; Humans; Isomeris

1983
The effects of single and repeated doses of maprotiline, oxaprotiline and its enantiomers on foot-shock induced fighting in rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:4

    Topics: Aggression; Animals; Anthracenes; Atropine; Cerebral Cortex; Electroshock; Humans; Male; Maprotiline

1983
Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism.
    Journal of neural transmission, 1981, Volume: 52, Issue:3

    Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brompheniramine; Clonidine; Drug Synergis

1981
The effects of antidepressants on aggressiveness induced by social deprivation in mice.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14 Suppl 1

    Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Imiprami

1981
Biphasic effects of typical antidepressants and mianserin, an atypical antidepressant, on aggressive behavior in socially isolated mice.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Clomipramine; Male; Mapr

1993
[Behavior pharmacology of maprotiline, a new antidepressant].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:8

    Topics: Aggression; Amitriptyline; Animals; Anthracenes; Apomorphine; Behavior, Animal; Body Temperature; Ca

1975
The suppression of olfactory bulbectomy-induced muricide by antidepressants and antihistamines via histamine H1 receptor blocking.
    Physiology & behavior, 1992, Volume: 51, Issue:6

    Topics: Aggression; Animals; Antidepressive Agents; Binding, Competitive; Cattle; Dose-Response Relationship

1992