Page last updated: 2024-08-22

mannose and Alzheimer Disease

mannose has been researched along with Alzheimer Disease in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's7 (50.00)2.80

Authors

AuthorsStudies
Hao, Y; Liu, X; Shi, Y; Su, C; Sui, H; Zhao, L1
Eriksson, J; Gustavsson, T; Robillard, M; Rokka, J; Rossin, R; Schlein, E; Sehlin, D; Syvänen, S1
Chang, S; Chu, X; Ding, J; Du, C; Feng, T; Ge, C; Geng, M; Gong, Y; Huang, X; Lian, W; Lin, F; Liu, J; Ruan, L; Sun, G; Wang, H; Wang, T; Wang, X; Xiao, S; Xie, Z; Yan, S; Yang, D; Yang, J; Zhang, G; Zhang, H; Zhang, J; Zhang, Q1
Syed, YY1
Itzhaki, RF1
Bi, J; Chen, H; Chen, K; Chen, W; Chen, Y; Cheng, Y; Ding, J; Du, Y; Gao, X; Geng, M; Guan, Y; He, Z; Huang, Q; Kuang, W; Li, H; Li, W; Li, Y; Lin, H; Peng, Y; Shi, S; Tang, M; Wang, B; Wang, T; Xiao, J; Xiao, S; Xin, X; Xu, W; Yan, C; Zhang, L; Zhou, H1
Auladell, C; Busquets, O; Camins, A; Cano, A; Casadesús, G; Castro-Torres, RD; Espinosa-Jimenez, T; Ettcheto, M; Folch, J; Manzine, PR; Olloquequi, J; Sánchez-Lopez, E; Sureda, FX; Verdaguer, E1
Cantillon, M; Chan, P; Chen, H; Chen, K; Chen, L; Chen, S; Chen, W; Chen, X; Cheng, X; Cheng, Y; Cong, L; Cui, R; Cummings, JL; Ding, J; Ding, Y; Du, Y; Fan, D; Feng, T; Gao, D; Gao, P; Geng, M; Guan, Y; Guo, Q; He, J; He, R; Hong, Z; Hu, H; Huang, Q; Ji, Y; Jia, J; Jiang, L; Jiao, B; Kuang, W; Li, S; Li, Y; Lian, T; Liu, C; Liu, S; Liu, X; Liu, Z; Lu, W; Luo, B; Mao, P; Ouyang, Y; Pan, X; Peng, D; Peng, G; Peng, Y; Qu, Q; Ren, W; Shen, L; Tang, H; Wang, L; Wang, Q; Wang, S; Wang, T; Wang, X; Wang, Y; Wu, W; Wu, Y; Xia, M; Xiao, J; Xiao, S; Xin, X; Xu, J; Xu, Q; Yan, Y; Ye, Q; Yin, Y; Zhang, H; Zhang, J; Zhang, N; Zhang, W; Zhang, X; Zhang, Y; Zhang, Z; Zhao, Q; Zhao, Z; Zhou, Y1
Belting, M; Bourseau-Guilmain, E; Cheng, F; Fransson, LÅ; Mani, K1
Belting, M; Cheng, F; Fransson, LÅ; Mani, K1
Annaert, W; Bentahir, M; Craessaerts, K; De Strooper, B; Herreman, A; Mueller, U; Nyabi, O; Van Gassen, G1
Kanapathipillai, M; Lentzen, G; Park, CB; Ryu, J1
Junaid, MA; Pullarkat, RK1
Endo, T; Grundke-Iqbal, I; Iqbal, K; Naito, Y; Sato, Y1

Reviews

2 review(s) available for mannose and Alzheimer Disease

ArticleYear
Sodium Oligomannate: First Approval.
    Drugs, 2020, Volume: 80, Issue:4

    Topics: Alzheimer Disease; Animals; China; Drug Approval; Humans; Mannose; Oligosaccharides

2020
Pharmacological Strategies to Improve Dendritic Spines in Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 82, Issue:s1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Dendritic Spines; Diet, Healthy; Exercise; Gastrointestinal Microbiome; Humans; Mannose; Oligosaccharides; Synapses

2021

Trials

2 trial(s) available for mannose and Alzheimer Disease

ArticleYear
A phase II randomized trial of sodium oligomannate in Alzheimer's dementia.
    Alzheimer's research & therapy, 2020, 09-14, Volume: 12, Issue:1

    Topics: Alzheimer Disease; China; Cholinesterase Inhibitors; Double-Blind Method; Humans; Mannose; Oligosaccharides; Sodium; Treatment Outcome

2020
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer's dementia.
    Alzheimer's research & therapy, 2021, 03-17, Volume: 13, Issue:1

    Topics: Activities of Daily Living; Alzheimer Disease; China; Cholinesterase Inhibitors; Double-Blind Method; Humans; Mannose; Oligosaccharides; Pharmaceutical Preparations; Sodium; Treatment Outcome

2021

Other Studies

10 other study(ies) available for mannose and Alzheimer Disease

ArticleYear
Bioengineered microglia-targeted exosomes facilitate Aβ clearance via enhancing activity of microglial lysosome for promoting cognitive recovery in Alzheimer's disease.
    Biomaterials advances, 2022, Volume: 136

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Bioengineering; Cognition; Exosomes; Lysosomes; Mannose; Mice; Microglia

2022
Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging.
    Molecular pharmaceutics, 2022, 11-07, Volume: 19, Issue:11

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Antibodies; Brain; Disease Progression; Immunoconjugates; Mannose; Mice; Mice, Transgenic; Neuroimaging; Positron-Emission Tomography

2022
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.
    Cell research, 2019, Volume: 29, Issue:10

    Topics: Alzheimer Disease; Amino Acids; Animals; Anti-Bacterial Agents; Bacteria; Clinical Trials, Phase III as Topic; Cognitive Dysfunction; Disease Models, Animal; Disease Progression; Gastrointestinal Microbiome; Humans; Isoleucine; Mannose; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Oligosaccharides; Phenylalanine; Th1 Cells

2019
Hypothesis: Does the Apparent Protective Action of Green Valley's Drug GV971 Against Cognitive Decline Result from Antiviral Action Against Herpes Simplex Virus Type 1 in Brain?
    Journal of Alzheimer's disease : JAD, 2020, Volume: 76, Issue:1

    Topics: Alzheimer Disease; Animals; Antiviral Agents; Brain; Cognitive Dysfunction; Herpesvirus 1, Human; Humans; Mannose; Neuroprotective Agents; Oligosaccharides; Virus Replication

2020
Hypoxia induces NO-dependent release of heparan sulfate in fibroblasts from the Alzheimer mouse Tg2576 by activation of nitrite reduction.
    Glycobiology, 2016, Volume: 26, Issue:6

    Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Ascorbic Acid; Cell Hypoxia; Deferoxamine; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Glypicans; Heparitin Sulfate; Humans; Iron Chelating Agents; Mannose; Mice; Mice, Transgenic; Microscopy, Fluorescence; Nitric Oxide; Nitrite Reductases; Nitrites; Oxidation-Reduction; Oxygen; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture

2016
Nucleolin is a nuclear target of heparan sulfate derived from glypican-1.
    Experimental cell research, 2017, 05-01, Volume: 354, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Nucleus; Disease Models, Animal; Endosomes; Glypicans; Heparitin Sulfate; Humans; Mannose; Mice; Microscopy, Confocal; Nitric Oxide; Nucleolin; Phosphoproteins; RNA-Binding Proteins

2017
gamma-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation.
    Journal of cell science, 2003, Mar-15, Volume: 116, Issue:Pt 6

    Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Endopeptidases; Fibroblasts; Gene Expression; Glycosylation; Golgi Apparatus; Humans; Kidney; Mannose; Membrane Glycoproteins; Membrane Proteins; Mice; Neurons; Oligosaccharides; Presenilin-1; Presenilin-2

2003
Inhibition of beta-amyloid peptide aggregation and neurotoxicity by alpha-d-mannosylglycerate, a natural extremolyte.
    Peptides, 2008, Volume: 29, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cells, Cultured; Glyceric Acids; Humans; Mannose; Microscopy, Atomic Force; Peptide Fragments

2008
Increased brain lysosomal pepstatin-insensitive proteinase activity in patients with neurodegenerative diseases.
    Neuroscience letters, 1999, Apr-02, Volume: 264, Issue:1-3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aminopeptidases; Animals; Brain; Child; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dog Diseases; Dogs; Endopeptidases; Female; Humans; Leukodystrophy, Globoid Cell; Male; Mannose; Middle Aged; Neurodegenerative Diseases; Neuronal Ceroid-Lipofuscinoses; Pepstatins; Peptide Hydrolases; Reference Values; Serine Proteases; Tripeptidyl-Peptidase 1

1999
Analysis of N-glycans of pathological tau: possible occurrence of aberrant processing of tau in Alzheimer's disease.
    FEBS letters, 2001, May-11, Volume: 496, Issue:2-3

    Topics: Alzheimer Disease; Animals; Blotting, Western; Brain; Carbohydrate Sequence; Cattle; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glycoside Hydrolases; Glycosylation; Humans; Mannose; Molecular Sequence Data; Oligosaccharides; ortho-Aminobenzoates; Phosphorylation; Polysaccharides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; tau Proteins; Time Factors

2001