mannomustine has been researched along with Leukemia--Lymphoid* in 8 studies
8 other study(ies) available for mannomustine and Leukemia--Lymphoid
| Article | Year |
|---|---|
[Effect of cyclophosphane, chlorbutin and degranol on protein biosynthesis in the lymphocytes of donors and chronic lympholeukemia patients in vitro].
The alkylating agents in different concentrations are studied for their effect on protein biosynthesis and the relative content of leu-tRNA. The rate of elongation and termination of polypeptide translation in lymphocytes of donors and of patients with chronic lymphoid leukemia in vitro is studied. The therapeutic doses of cyclophosphamide are shown to inhibit the amino acid incorporation into acid insoluble pool of predominantly leukemic lymphocytes, while chlorbutin and degranol caused the greater suppression of the amino acid incorporation into healthy cells. Chlorbutin, cyclophosphamide and degranol in doses above therapeutic caused approximately 95, 48 and 34% inhibition of the protein synthesis, respectively. The mechanism of action on the translation is different. Only chlorbutin acted directly on the translation rate and also increased leu-tRNA content. Degranol decreased the leu-tRNA content. Cyclophosphamide produces no effect on these processes in vitro. Topics: Alkylating Agents; Amino Acids; Blood Donors; Blood Proteins; Chlorambucil; Cyclophosphamide; Depression, Chemical; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphoid; Lymphocytes; Mannomustine; Protein Biosynthesis | 1985 |
Secondary antibody deficiency syndrome in haemoblastosis.
Topics: Agammaglobulinemia; Antibodies; Antigens, Bacterial; Blood Protein Disorders; Blood Proteins; Busulfan; Chlorambucil; Electrophoresis, Paper; Hodgkin Disease; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulins; Immunosuppression Therapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mannomustine; Melphalan; Primary Myelofibrosis; Radiation Effects; Saliva; Skin Tests; Spleen; Time Factors | 1972 |
[Use of the kinetic method for evaluation of the effectiveness of treating chronic leukemia patients with myelosan and degranol and their effect on the hemogram].
Topics: Busulfan; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mannomustine; Mathematics | 1971 |
[CLINICAL TESTING OF THE THERAPEUTIC EFFECT OF 1,6-BIS(2-MESYLOXYETHYLAMINO) 1,6-DIDESOXY-D-MANNITOL DI-HC1 (R 49)].
Topics: Antineoplastic Agents; Blood Cell Count; Blood Platelets; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Leukopenia; Lymphadenitis; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mannitol; Mannomustine; Neoplasms; Radiography, Thoracic; Sarcoma; Thrombocytopenia; Toxicology | 1964 |
EXPERIENCE WITH CHEMOTHERAPY OF CANCER AT THE UNIVERSITY OF PRETORIA.
Topics: Antineoplastic Agents; Aziridines; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Fluorouracil; Hodgkin Disease; Humans; Intestinal Neoplasms; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Non-Hodgkin; Mannomustine; Mesothelioma; Multiple Myeloma; Neoplasms; Pancreatic Neoplasms; Sarcoma; South Africa; Stomach Neoplasms; Vinblastine | 1964 |
[The use of Degranol pills in hemoblastosis and other neoplastic diseases].
Topics: Humans; Leukemia; Leukemia, Lymphoid; Lymphogranuloma Venereum; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mannomustine; Neoplasms; Prednisone; Sarcoma | 1963 |
[EXAMINATION OF THE STEROID METABOLISM IN HUMAN LEUKEMIA].
Topics: 17-Ketosteroids; Androgens; Busulfan; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocytes; Mannomustine; Prednisolone; Urine | 1963 |
Clinical evaluation of the effect of degranol.
Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mannitol; Mannomustine; Mechlorethamine; Nitrogen Mustard Compounds | 1959 |