mangostin and Leukemia--Myeloid--Acute

Immunogenic cell death (ICD), one of cell-death types through release of damage-associated molecular patterns from dying tumor cells, activates tumor-specific immune response and elicits anti-tumor immunity by traditional radiotherapy and chemotherapy. However, whether natural products could induce ICD in leukemia is not elucidated. Here, we report dietary γ-mangostin eradicates murine primary leukemic cells and prolongs the survival of leukemic mice. As well, it restrains primary leukemic cells and CD34

Topics: Animals; Chemokines; Diet; Humans; Immunogenic Cell Death; Leukemia, Myeloid, Acute; Mice; Tumor Microenvironment