mangostin and Helicobacter-Infections

mangostin has been researched along with Helicobacter-Infections* in 1 studies

Other Studies

1 other study(ies) available for mangostin and Helicobacter-Infections

Article	Year
Combating Helicobacter pylori infections with mucoadhesive nanoparticles loaded with Garcinia mangostana extract. Nanomedicine (London, England), 2014, Volume: 9, Issue:3 To combat the resistance of Helicobacter pylori to antibiotics through the use of Garcinia mangostana extract (GME) in the form that can be localized at stomach mucosa.. GME and its major active component, α-mangostin, are encapsulated into the moderately acid stable mucoadhesive nanocarriers, and tested for anti-H. pylori and antiadhesion activities in vitro and their ability to eradicate H. pylori in infected mice.. The two in vitro activities are observed and are enhanced when the materials are encapsulated into nanocarriers. Preliminary in vivo tests revealed the ability to combat H. pylori in mice following oral administration of the encapsulated GME, but not the unencapsulated GME.. Nanoencapsulated GME is a potential anti-H. pylori agent. Topics: Adhesins, Bacterial; Animals; Cell Line; Drug Carriers; Garcinia mangostana; Helicobacter Infections; Helicobacter pylori; Humans; Mice; Mice, Inbred C57BL; Nanoparticles; Plant Extracts; Stomach; Xanthones	2014

Article

Year

Combating Helicobacter pylori infections with mucoadhesive nanoparticles loaded with Garcinia mangostana extract.

Nanomedicine (London, England), 2014, Volume: 9, Issue:3

To combat the resistance of Helicobacter pylori to antibiotics through the use of Garcinia mangostana extract (GME) in the form that can be localized at stomach mucosa.. GME and its major active component, α-mangostin, are encapsulated into the moderately acid stable mucoadhesive nanocarriers, and tested for anti-H. pylori and antiadhesion activities in vitro and their ability to eradicate H. pylori in infected mice.. The two in vitro activities are observed and are enhanced when the materials are encapsulated into nanocarriers. Preliminary in vivo tests revealed the ability to combat H. pylori in mice following oral administration of the encapsulated GME, but not the unencapsulated GME.. Nanoencapsulated GME is a potential anti-H. pylori agent.

Topics: Adhesins, Bacterial; Animals; Cell Line; Drug Carriers; Garcinia mangostana; Helicobacter Infections; Helicobacter pylori; Humans; Mice; Mice, Inbred C57BL; Nanoparticles; Plant Extracts; Stomach; Xanthones

2014