Page last updated: 2024-08-22

manganese and Parkinsonian Disorders

manganese has been researched along with Parkinsonian Disorders in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.13)18.7374
1990's0 (0.00)18.2507
2000's18 (28.13)29.6817
2010's34 (53.13)24.3611
2020's10 (15.63)2.80

Authors

AuthorsStudies
Aschner, M; Gurol, KC; Mukhopadhyay, S; Smith, DR1
Fujishiro, H; Kambe, T1
Edler, MK; Guilarte, TR; McGlothan, JL; Rodichkin, AN1
Guilarte, TR; Rodichkin, AN1
Chen, M; Deng, P; Lu, M; Mei, X; Pi, H; Wang, X; Wu, L; Yang, L; Yu, Z; Zhou, C; Zhou, Z1
Lucchini, R; Tieu, K1
Ratner, MH; Rutchik, J1
Ennok, M; Haldre, S; Sikk, K; Taba, P1
Cao, B; Li, J; Li, SJ; Li, XR; Ma, C; Qin, SS; Ren, YD1
Bouwer, EJ; Freeman, DM; O'Neal, R; Wang, Z; Zhang, Q1
Checkoway, H; Criswell, SR; Lenox-Krug, J; Moerlein, SM; Nielsen, SS; Perlmutter, JS; Racette, BA; Sheppard, L; Warden, MN1
Blanc, PD1
Anantharam, V; Ay, M; Ghaisas, S; Jin, H; Kanthasamy, A; Kanthasamy, AG; Langley, MR; Luo, J; Palanisamy, BN1
Ang, ET; Asad, ABA; Chai, BH; Chew, KCM; Chuang, KH; Hong, ETE; Lim, KL; Soong, TW; Tai, YK; Tan, BWQ; Tsang, F; Zhang, CW1
Caudle, WM1
Agrawal, PB; Al-Jasmi, F; Berry, GT; Cao, S; D'Gama, AM; Gropman, A; Hauptman, M; Hayflick, SJ; Hertecant, J; Qualls, AE; Rodan, LH; Tuschl, K; Wessling-Resnick, M; Woolf, AD; Yang, ET1
Checkoway, H; Criswell, SR; Lenox-Krug, J; Moerlein, SM; Perlmutter, JS; Racette, BA; Searles Nielsen, S; Sheppard, L; Warden, MN1
Carmona, A; Cloetens, P; Garrevoet, J; Mukhopadhyay, S; Ortega, R; Porcaro, F; Roudeau, S; Salomé, M; Spiers, KM; Zogzas, CE1
Bailey, RA; Gutierrez, A; Hemmerle, AM; Hufgard, JR; Kyser, TL; Seroogy, KB; Vorhees, CV; Williams, MT1
Aschner, M; Avila, DS; Puntel, RL1
Golasik, M; Gomółka, E; Herman, M; Piekoszewski, W; Wodowski, G1
Bergquist, J; Bonnet, C; Botchorishvili, N; Brožová, H; Fiala, O; Gaymard, B; Hanuška, J; Janelidze, M; Jech, R; Kapianidze, M; Khatiashvili, I; Matoušková, O; Megrelishvili, M; Mikeladze, N; Nikolai, T; Okujava, M; Rivaud-Péchoux, S; Roth, J; Rusz, J; Růžička, E; Serranová, T; Sieger, T1
Roth, JA1
Aschner, M; Bowman, AB; Chen, P; Hutchens, S; Leyva-Illades, D; Mercado, JM; Morrisett, RA; Mukhopadhyay, S; Swaim, CD; Zogzas, CE1
Bałasz, M; Brus, R; Kasperczyk, S; Kostrzewa, RM; Malinowska-Borowska, J; Nowak, D; Nowak, P; Szkilnik, R1
Daniel, G; Fiser, A; Glauser, L; Moore, DJ; Musso, A; Pletnikova, O; Schneider, BL; Tsika, E1
Gonzales, KK; Guilarte, TR1
Guo, S; Huang, W; Pang, L; Wang, J1
Fukutake, T; Kushida, R; Sunada, Y; Yano, H1
Michalke, B1
Abdul-Sada, A; Bodamer, OA; Chong, WK; Clayton, PT; Coroleu-Lletget, W; Cuno, SM; Dadswell, C; Dale, RC; Eaton, S; Enns, CA; Gissen, P; Gregory, A; Hayflick, SJ; Houlden, H; Hung, CY; Jacques, TS; Kara, E; Kurian, MA; Maher, ER; Meyer, E; Mills, PB; Mohammad, SS; Pintos-Morell, G; Prokisch, H; Rihel, J; Sanford, L; Selim, LA; Simpson, MA; Spencer, J; Straatman-Iwanowska, A; Thomas, M; Tiranti, V; Tuschl, K; Valdivia, LE; Valletta, L; Wilson, SW; Woltjer, RL; Yoganathan, S; Younis, R; Zhao, N1
Bade, AN; Boska, MD; Dong, J; Gendelman, HE; Liu, Y; Mosley, RL; Olson, KE; Schutt, CR; Shandler, SJ1
Balint, B; Bhatia, KP1
Fitzgerald, E; Ratner, MH1
Fedoryshyn, L; Friedman, A; Jäger, HR; Komnatska, I; Krolicki, L; Kyrylchuk, M; Lees, A; Matviyenko, Y; Sanotsky, Y; Selikhova, M; Taylor, A1
Alexander, M; Burton, NC; Griswold, M; Guilarte, TR; McGlothan, JL; Pham, L; Schneider, JS; Syversen, T; Verina, T; Wong, DF; Zhou, Y1
Alberici, A; Albini, E; Alessio, L; Benussi, L; Binetti, G; Bucossi, S; Draicchio, F; Gorgone, G; Lucchini, R; Melgari, JM; Panetta, V; Rossini, PM; Squitti, R1
Aquilonius, SM; Askmark, H; Bergquist, J; Danfors, T; Eriksson, R; Färnstrand, C; Flink, R; Haldre, S; Nyholm, D; Raininko, R; Sikk, K; Sörensen, J; Taba, P; Thurfjell, L1
Bonilla-Ramirez, L; Jimenez-Del-Rio, M; Velez-Pardo, C1
Chi, J; Hu, D; Jiang, L; Pan, Q; Tan, J; Wang, D; Zhang, T; Zhang, Z1
Aoun, RA; Khalid, M; Mathews, TA1
Hong, L; Jiang, W; Jiang, Y; Pan, H; Zeng, S; Zheng, W1
Adwent, M; Boroń, D; Brus, H; Brus, R; Jochem, J; Kostrzewa, RM; Nowak, P1
Bollweg, G; Bowler, RM; Davis, SI; Gocheva, V; Harris, M; Kim, Y; Lobdell, DT; Ngo, L; Roels, HA; Wilson, K1
Battisti, C; Bonifati, V; Breedveld, GJ; Cossu, G; Delnooz, C; Di Toro Mammarella, L; Federico, A; Lu, P; Mignarri, A; Monti, L; Oostra, BA; Punzo, F; Quadri, M; Rasi, F; Sanna, A; Severijnen, LA; van de Warrenburg, BP; Willemsen, R; Zhao, T1
Bonetti, G; Lucchini, R; Zoni, S1
Aschner, M; Chen, P; DeWitt, MR1
Barreto, WJ; Blum, D; Britto, LR; Gaziri, LC; Ponzoni, S1
Gwiazda, RH; Lee, D; Sheridan, J; Smith, DR1
Arakawa, T; Higuchi, K; Iimuro, M; Inagawa, M; Jinno, Y; Kamata, N; Kawachiya, T; Kawashima, D; Matsumoto, T; Nakamura, S; Oiso, R; Oshitani, N; Sogawa, M; Watanabe, K1
Hamanaka, M; Matsumoto, M; Nakagawa, M; Yoshikawa, K1
TURNER, JW1
Olanow, CW1
de la Fuente-Fernández, R1
Ahlskog, JE; Cowl, CT; Fealey, RD; Josephs, KA; Klos, KJ; Kumar, N; Trenerry, MR1
Carmellino, C; Chiò, A; Discalzi, G; Herrero Hernandez, E; Pira, E; Rossi, L; Sacchetti, A; Valentini, C; Venturi, F1
Bowler, RM; Koller, W; Schulz, PE1
Norenberg, MD; Rao, KV1
Choi, SH; Kim, J; Kim, JM; Kim, SE; Kim, Y; Kim, YK; Shin, JW1
Albini, E; Alessio, L; Benedetti, L; Borghesi, S; Coccaglio, R; Garattini, S; Lucchini, RG; Malara, EC; Parrinello, G; Resola, S1
Ammassari-Teule, M; Bernardi, G; Calabresi, P; Centonze, D; Gubellini, P; Marfia, GA; Morello, M; Passino, E; Picconi, B; Sancesario, G; Saulle, E1
Purdham, JT; Roels, HA; Verma, DK1
Burkhard, P; Delavelle, J; DuPasquier, R; Giostra, E; Hadengue, A; Hochstrasser, D; Lazeyras, F; Mentha, G; Spahr, L; Terrier, F; Vingerhoets, F1

Reviews

15 review(s) available for manganese and Parkinsonian Disorders

ArticleYear
Role of excretion in manganese homeostasis and neurotoxicity: a historical perspective.
    American journal of physiology. Gastrointestinal and liver physiology, 2022, 01-01, Volume: 322, Issue:1

    Topics: Cation Transport Proteins; Homeostasis; Humans; Manganese; Metals; Mutation; Parkinsonian Disorders

2022
Manganese transport in mammals by zinc transporter family proteins, ZNT and ZIP.
    Journal of pharmacological sciences, 2022, Volume: 148, Issue:1

    Topics: Animals; Cation Transport Proteins; Gene Expression Regulation; Homeostasis; Humans; Mammals; Manganese; Mutation; Parkinsonian Disorders; Phenotype

2022
Hereditary Disorders of Manganese Metabolism: Pathophysiology of Childhood-Onset Dystonia-Parkinsonism in
    International journal of molecular sciences, 2022, Oct-24, Volume: 23, Issue:21

    Topics: Animals; Cation Transport Proteins; Dystonia; Dystonic Disorders; Humans; Ions; Manganese; Mice; Models, Animal; Mutation; Parkinsonian Disorders; Zebrafish

2022
Manganese-Induced Parkinsonism: Evidence from Epidemiological and Experimental Studies.
    Biomolecules, 2023, 07-30, Volume: 13, Issue:8

    Topics: Genetic Predisposition to Disease; Humans; Manganese; Parkinson Disease; Parkinsonian Disorders

2023
The early history of manganese and the recognition of its neurotoxicity, 1837-1936.
    Neurotoxicology, 2018, Volume: 64

    Topics: Animals; Hepatolenticular Degeneration; History, 19th Century; History, 20th Century; Humans; Manganese; Manganese Poisoning; Occupational Exposure; Parkinsonian Disorders

2018
Occupational Metal Exposure and Parkinsonism.
    Advances in neurobiology, 2017, Volume: 18

    Topics: Copper; Heavy Metal Poisoning, Nervous System; Humans; Iron; Lead Poisoning, Nervous System; Manganese; Manganese Poisoning; Metal Nanoparticles; Occupational Exposure; Parkinsonian Disorders

2017
Manganese in health and disease.
    Metal ions in life sciences, 2013, Volume: 13

    Topics: Animals; Antioxidants; Cell Death; Dopaminergic Neurons; Humans; Manganese; Manganese Poisoning; Parkinsonian Disorders

2013
Correlation between the biochemical pathways altered by mutated parkinson-related genes and chronic exposure to manganese.
    Neurotoxicology, 2014, Volume: 44

    Topics: alpha-Synuclein; Animals; Cation Transport Proteins; Environmental Exposure; Humans; Intracellular Signaling Peptides and Proteins; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Manganese; Mice; Mutation; Oncogene Proteins; Parkinsonian Disorders; Protein Deglycase DJ-1; Protein Kinases; Protein Serine-Threonine Kinases; Proton-Translocating ATPases; Risk Factors; Signal Transduction; Ubiquitin-Protein Ligases; Vesicular Transport Proteins; Zinc Transporter 8

2014
Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 146, Issue:2

    Topics: Animals; Corpus Striatum; Dopamine; Manganese; Parkinsonian Disorders; Substantia Nigra

2015
[Early Detection of Manganese Intoxication Based on Occupational History and T1-weighted MRI].
    Brain and nerve = Shinkei kenkyu no shinpo, 2016, Volume: 68, Issue:2

    Topics: Brain; Early Diagnosis; Humans; Magnetic Resonance Imaging; Manganese; Manganese Poisoning; Parkinsonian Disorders

2016
Review about the manganese speciation project related to neurodegeneration: An analytical chemistry approach to increase the knowledge about manganese related parkinsonian symptoms.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2016, Volume: 37

    Topics: Animals; Humans; Manganese; Neurons; Oxidative Stress; Parkinsonian Disorders

2016
Manganese-Enhanced Magnetic Resonance Imaging for Detection of Vasoactive Intestinal Peptide Receptor 2 Agonist Therapy in a Model of Parkinson's Disease.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2016, Volume: 13, Issue:3

    Topics: Animals; Brain; Dopaminergic Neurons; Image Enhancement; Magnetic Resonance Imaging; Male; Manganese; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Oligopeptides; Parkinson Disease; Parkinsonian Disorders; Protein-Tyrosine Kinases; Receptors, Vasoactive Intestinal Peptide, Type II

2016
Manganese-induced parkinsonism and Parkinson's disease.
    Annals of the New York Academy of Sciences, 2004, Volume: 1012

    Topics: Animals; Brain; Humans; Magnetic Resonance Imaging; Manganese; Manganese Poisoning; Parkinson Disease; Parkinsonian Disorders; Tomography, Emission-Computed, Single-Photon

2004
The mitochondrial permeability transition in neurologic disease.
    Neurochemistry international, 2007, Volume: 50, Issue:7-8

    Topics: Alzheimer Disease; Calcium; Energy Metabolism; Humans; Huntington Disease; Hyperglycemia; Manganese; Mitochondrial Membranes; Mitochondrial Swelling; Motor Neuron Disease; Nervous System Diseases; Neurodegenerative Diseases; Neurotoxins; Parkinsonian Disorders; Permeability

2007
Translating evidence about occupational conditions into strategies for prevention.
    Occupational and environmental medicine, 2002, Volume: 59, Issue:3

    Topics: 2-Naphthylamine; Alkanes; Asbestos; Asbestosis; Carcinogens; Hearing Loss, Noise-Induced; Humans; Industry; Manganese; Neoplasms; Noise; Occupational Diseases; Occupational Exposure; Parkinsonian Disorders; Pneumonia; Safety Management; Silicon Dioxide; Silicosis; Vinyl Chloride

2002

Trials

1 trial(s) available for manganese and Parkinsonian Disorders

ArticleYear
Follow-up of patients affected by manganese-induced Parkinsonism after treatment with CaNa2EDTA.
    Neurotoxicology, 2006, Volume: 27, Issue:3

    Topics: Adult; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Manganese; Middle Aged; Parkinsonian Disorders; Retrospective Studies; Welding

2006

Other Studies

48 other study(ies) available for manganese and Parkinsonian Disorders

ArticleYear
Pathophysiological studies of aging Slc39a14 knockout mice to assess the progression of manganese-induced dystonia-parkinsonism.
    Neurotoxicology, 2022, Volume: 93

    Topics: Aging; Animals; Cation Transport Proteins; Dystonia; Humans; Manganese; Mice; Mice, Knockout; Parkinsonian Disorders; Substantia Nigra

2022
Manganese overexposure induces Parkinson-like symptoms, altered lipid signature and oxidative stress in C57BL/6 J mouse.
    Ecotoxicology and environmental safety, 2023, Sep-15, Volume: 263

    Topics: Animals; Humans; Lipids; Male; Manganese; Mice; Mice, Inbred C57BL; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders

2023
Should Age at Onset of Parkinsonism be the End Point of Interest in Investigations of the Link Between Exosomal α-Synuclein and Manganese Exposure in Welders?
    Journal of occupational and environmental medicine, 2019, Volume: 61, Issue:12

    Topics: Adult; Age of Onset; Aged; alpha-Synuclein; Humans; Manganese; Middle Aged; Occupational Exposure; Parkinsonian Disorders; Trace Elements; Welding

2019
Cognitive profile of patients with manganese-methcathinone encephalopathy.
    Neurotoxicology, 2020, Volume: 76

    Topics: Adolescent; Adult; Brain Diseases; Cognition; Cognitive Dysfunction; Female; Humans; Male; Manganese; Neuropsychological Tests; Parkinsonian Disorders; Propiophenones; Young Adult

2020
The role of iron in Parkinson's disease monkeys assessed by susceptibility weighted imaging and inductively coupled plasma mass spectrometry.
    Life sciences, 2020, Jan-01, Volume: 240

    Topics: Animals; Behavior, Animal; Brain; Calcium; Iron; Macaca fascicularis; Magnetic Resonance Imaging; Male; Manganese; Mass Spectrometry; MPTP Poisoning; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase

2020
Manganese-induced Parkinsonism in mice is reduced using a novel contaminated water sediment exposure model.
    Environmental toxicology and pharmacology, 2020, Volume: 78

    Topics: Animals; Behavior, Animal; Female; Geologic Sediments; Male; Manganese; Mice, Inbred C57BL; Parkinsonian Disorders; Sex Characteristics; Water Pollutants, Chemical

2020
[11C]dihydrotetrabenazine Positron Emission Tomography in Manganese-Exposed Workers.
    Journal of occupational and environmental medicine, 2020, Volume: 62, Issue:10

    Topics: Adult; Aged; Carbon Radioisotopes; Female; Humans; Male; Manganese; Middle Aged; Occupational Diseases; Occupational Exposure; Parkinsonian Disorders; Positron-Emission Tomography; Tetrabenazine; Young Adult

2020
Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.
    Neurotoxicology, 2018, Volume: 64

    Topics: Animals; Behavior, Animal; Cell Line; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Female; Gene-Environment Interaction; Male; Manganese; Mice, Transgenic; Mitochondria; Motor Activity; Oxidative Stress; Parkinson Disease, Secondary; Parkinsonian Disorders; Substantia Nigra

2018
Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain.
    Neuromolecular medicine, 2017, Volume: 19, Issue:2-3

    Topics: Animals; Cation Transport Proteins; Gene Expression Regulation; Iron; Macaca fascicularis; Manganese; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidopamine; Parkinsonian Disorders; Prions; Promoter Regions, Genetic; Recombinant Proteins; Rotarod Performance Test; Substantia Nigra; Ubiquitin-Protein Ligases

2017
Novel founder intronic variant in SLC39A14 in two families causing Manganism and potential treatment strategies.
    Molecular genetics and metabolism, 2018, Volume: 124, Issue:2

    Topics: Cation Transport Proteins; Chelating Agents; Child; Child, Preschool; Dystonic Disorders; Female; Humans; Male; Manganese; Metal Metabolism, Inborn Errors; Mutation; Parkinsonian Disorders; Pedigree

2018
Selective D2 receptor PET in manganese-exposed workers.
    Neurology, 2018, 09-11, Volume: 91, Issue:11

    Topics: Adult; Aged; Benperidol; Brain; Case-Control Studies; Female; Humans; Male; Manganese; Manganese Poisoning; Middle Aged; Multimodal Imaging; Neuroimaging; Parkinsonian Disorders; Positron-Emission Tomography; Receptors, Dopamine D2; Young Adult

2018
SLC30A10 Mutation Involved in Parkinsonism Results in Manganese Accumulation within Nanovesicles of the Golgi Apparatus.
    ACS chemical neuroscience, 2019, 01-16, Volume: 10, Issue:1

    Topics: Cation Transport Proteins; Golgi Apparatus; Humans; Manganese; Mutation; Neurotoxicity Syndromes; Parkinsonian Disorders; Protein Transport

2019
Effects of Preweaning Manganese in Combination with Adult Striatal Dopamine Lesions on Monoamines, BDNF, TrkB, and Cognitive Function in Sprague-Dawley Rats.
    Neurotoxicity research, 2019, Volume: 35, Issue:3

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Dopamine; Female; Male; Manganese; Maternal Nutritional Physiological Phenomena; Memory Disorders; Norepinephrine; Oxidopamine; Parkinsonian Disorders; Random Allocation; Rats, Sprague-Dawley; Receptor, trkB; Sex Characteristics; Weaning

2019
Urine as a material for evaluation of exposure to manganese in methcathinone users.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2014, Volume: 28, Issue:3

    Topics: Humans; Manganese; Parkinsonian Disorders; Propiophenones; Spectrophotometry, Atomic

2014
Eye movements in ephedrone-induced parkinsonism.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Adult; Basal Ganglia; Brain; Eye Movements; Female; Humans; Male; Manganese; Middle Aged; Parkinsonian Disorders; Propiophenones; Saccades; Substance-Related Disorders

2014
SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Oct-15, Volume: 34, Issue:42

    Topics: Animals; Caenorhabditis elegans; Cation Transport Proteins; Cell Membrane; Cells, Cultured; Female; HeLa Cells; Humans; Intracellular Fluid; Male; Manganese; Mice, Inbred C57BL; Mutation; Parkinsonian Disorders; Protein Transport; Zinc Transporter 8

2014
Perinatal manganese exposure and hydroxyl radical formation in rat brain.
    Neurotoxicity research, 2015, Volume: 27, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Female; Frontal Lobe; Hippocampus; Hydroxyl Radical; Male; Manganese; Neostriatum; Oxidopamine; Parkinsonian Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar

2015
α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9).
    Neurobiology of disease, 2015, Volume: 73

    Topics: Aged; Aged, 80 and over; alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Female; Humans; Hydrogen Peroxide; Male; Manganese; Middle Aged; Neuroprotective Agents; Parkinsonian Disorders; Pregnancy; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Tissue Banks

2015
[A study of divalent metal transporter 1 and ferroportin 1 in brain of rats with manganese-induced parkinsonism].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2015, Volume: 33, Issue:4

    Topics: Animals; Cation Transport Proteins; Disease Models, Animal; Manganese; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra

2015
Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia.
    Nature communications, 2016, 05-27, Volume: 7

    Topics: Adolescent; Animals; Cation Transport Proteins; Child; Child, Preschool; Dystonic Disorders; Female; Genetic Predisposition to Disease; HEK293 Cells; Homeostasis; Humans; Male; Manganese; Mutation; Parkinsonian Disorders; Pedigree; Young Adult; Zebrafish

2016
SLC39A14 mutations expand the spectrum of manganese transporter defects causing parkinsonism-dystonia.
    Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:11

    Topics: Dystonia; Dystonic Disorders; Humans; Manganese; Mutation; Parkinsonian Disorders

2016
Understanding of the role of manganese in parkinsonism and Parkinson disease.
    Neurology, 2017, 01-24, Volume: 88, Issue:4

    Topics: Humans; Manganese; Manganese Poisoning; Parkinson Disease; Parkinson Disease, Secondary; Parkinsonian Disorders

2017
Parkinsonism and dystonia caused by the illicit use of ephedrone--a longitudinal study.
    Movement disorders : official journal of the Movement Disorder Society, 2008, Nov-15, Volume: 23, Issue:15

    Topics: Adolescent; Adult; Brain; Dystonic Disorders; Humans; Illicit Drugs; Longitudinal Studies; Magnetic Resonance Imaging; Male; Manganese; Middle Aged; Neurologic Examination; Parkinsonian Disorders; Propiophenones; Tomography, Emission-Computed, Single-Photon; Young Adult

2008
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism.
    Journal of neurochemistry, 2008, Volume: 107, Issue:5

    Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Macaca fascicularis; Male; Manganese; Parkinsonian Disorders; Positron-Emission Tomography; Substantia Nigra; Synaptic Transmission; Tetrabenazine; Tyrosine 3-Monooxygenase

2008
Rough manganic parkinsonism.
    Le Medecin d'usine; revue d'hygiene industrielle et des maladies professionnelles, 1948, Volume: 10, Issue:3

    Topics: Manganese; Manganese Poisoning; Occupations; Parkinsonian Disorders

1948
Implications of metal exposure and liver function in Parkinsonian patients resident in the vicinities of ferroalloy plants.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:10

    Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Copper; Environmental Exposure; Female; Humans; Iron; Italy; Liver; Male; Manganese; Metals, Heavy; Middle Aged; Parkinsonian Disorders; Peroxides; Severity of Illness Index; Time Factors; Transferrin; Zinc

2009
Clinical, neuroimaging and neurophysiological features in addicts with manganese-ephedrone exposure.
    Acta neurologica Scandinavica, 2010, Volume: 121, Issue:4

    Topics: Adult; Basal Ganglia Diseases; Corpus Striatum; Female; Humans; Magnetic Resonance Imaging; Male; Manganese; Manganese Poisoning; Neural Pathways; Parkinsonian Disorders; Peripheral Nervous System; Positron-Emission Tomography; Propiophenones; Substance-Related Disorders; Tomography, Emission-Computed, Single-Photon

2010
Acute and chronic metal exposure impairs locomotion activity in Drosophila melanogaster: a model to study Parkinsonism.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2011, Volume: 24, Issue:6

    Topics: Animals; Brain; Chelating Agents; Copper; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Female; Iron; Life Expectancy; Manganese; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Parkinsonian Disorders

2011
Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein.
    The Journal of biological chemistry, 2011, Aug-26, Volume: 286, Issue:34

    Topics: Animals; Brain; Cell Death; Cytochromes c; Cytosol; HEK293 Cells; Homeostasis; Humans; Manganese; Mitochondria; Mutation; Nerve Tissue Proteins; Neurons; Parkinsonian Disorders; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley

2011
Altered striatal dopamine release following a sub-acute exposure to manganese.
    Journal of neuroscience methods, 2011, Nov-15, Volume: 202, Issue:2

    Topics: Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Manganese; Manganese Poisoning; Mice; Mice, Inbred C57BL; Parkinsonian Disorders

2011
Brain regional pharmacokinetics of p-aminosalicylic acid and its N-acetylated metabolite: effectiveness in chelating brain manganese.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:10

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Antitubercular Agents; Brain; Chelating Agents; Chromatography, High Pressure Liquid; Infusions, Intravenous; Male; Manganese; Parkinsonian Disorders; Protein Binding; Rats; Rats, Sprague-Dawley

2011
Effect of pre- and postnatal manganese exposure on brain histamine content in a rodent model of Parkinson's disease.
    Neurotoxicity research, 2012, Volume: 21, Issue:2

    Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Dopamine; Drinking Water; Female; Histamine; Male; Manganese; Maternal Exposure; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Rats, Wistar

2012
Anxiety affecting parkinsonian outcome and motor efficiency in adults of an Ohio community with environmental airborne manganese exposure.
    International journal of hygiene and environmental health, 2012, Volume: 215, Issue:3

    Topics: Adult; Aged; Air Pollutants; Air Pollution; Anxiety; Biomarkers; Female; Humans; Hypokinesia; Male; Manganese; Middle Aged; Occupational Exposure; Ohio; Parkinsonian Disorders

2012
Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease.
    American journal of human genetics, 2012, Mar-09, Volume: 90, Issue:3

    Topics: Aged; Amino Acid Sequence; Brain; Cation Transport Proteins; Chromosome Mapping; Female; Frameshift Mutation; Genes, Recessive; Genetic Predisposition to Disease; Hep G2 Cells; Homozygote; Humans; Immunohistochemistry; Liver; Male; Manganese; Manganese Poisoning; Membrane Transport Proteins; Metabolic Diseases; Middle Aged; Molecular Sequence Data; Parkinsonian Disorders; Phenotype; Sequence Alignment; Tumor Cells, Cultured; Zinc Transporter 8

2012
Olfactory functions at the intersection between environmental exposure to manganese and Parkinsonism.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2012, Volume: 26, Issue:2-3

    Topics: Environmental Exposure; Humans; Manganese; Olfaction Disorders; Parkinsonian Disorders

2012
Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations.
    Biochemical and biophysical research communications, 2013, Mar-01, Volume: 432, Issue:1

    Topics: Cation Transport Proteins; Humans; Ion Transport; Manganese; Mutation; Parkinsonian Disorders; Zinc Transporter 8

2013
Clearance of manganese from the rat substantia nigra following intra-nigral microinjections.
    Neuroscience letters, 2002, Aug-09, Volume: 328, Issue:2

    Topics: Animals; Apomorphine; Cell Death; Chlorides; Dopamine; Dopamine Agonists; Gliosis; Immunohistochemistry; Male; Manganese; Manganese Compounds; Manganese Poisoning; Metabolic Clearance Rate; Microinjections; Neurons; Parkinsonian Disorders; Rats; Rats, Inbred Strains; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase

2002
Low cumulative manganese exposure affects striatal GABA but not dopamine.
    Neurotoxicology, 2002, Volume: 23, Issue:1

    Topics: Animals; Corpus Striatum; Dopamine; Drug Administration Schedule; Drug Synergism; Environmental Exposure; Female; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Manganese; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley

2002
Crohn's disease with Parkinsonism due to long-term total parenteral nutrition.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:5

    Topics: Crohn Disease; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Manganese; Middle Aged; Parenteral Nutrition; Parkinsonian Disorders; Risk Assessment; Severity of Illness Index; Short Bowel Syndrome

2003
A case of manganese induced parkinsonism in hereditary haemorrhagic telangiectasia.
    Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:9

    Topics: Adult; Female; Humans; Liver; Magnetic Resonance Imaging; Manganese; Parkinsonian Disorders; Telangiectasia, Hereditary Hemorrhagic

2003
PARKINSONISM: AETIOLOGY AND TREATMENT.
    London Clinic medical journal, 1964, Volume: 5

    Topics: Carbon Monoxide Poisoning; Craniocerebral Trauma; Drug Therapy; Encephalitis; Intracranial Arteriosclerosis; Manganese; Neurosurgery; Neurosurgical Procedures; Orphenadrine; Parasympatholytics; Parkinsonian Disorders; Reserpine; Stereotaxic Techniques; Syphilis; Toxicology; Trihexyphenidyl

1964
Portal-systemic shunts, manganese, and parkinsonism.
    Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75, Issue:7

    Topics: Adult; Basal Ganglia; Female; Humans; Magnetic Resonance Imaging; Manganese; Parkinsonian Disorders; Portasystemic Shunt, Surgical; Telangiectasia, Hereditary Hemorrhagic

2004
Neurologic manifestations in welders with pallidal MRI T1 hyperintensity.
    Neurology, 2005, Jun-28, Volume: 64, Issue:12

    Topics: Adult; Chelation Therapy; Cognition Disorders; Frontal Lobe; Globus Pallidus; Humans; Magnetic Resonance Imaging; Male; Manganese; Manganese Poisoning; Middle Aged; Myoclonus; Neuropsychological Tests; Occupational Exposure; Parkinsonian Disorders; Predictive Value of Tests; Treatment Outcome; Vestibular Diseases; Welding

2005
Parkinsonism due to manganism in a welder: neurological and neuropsychological sequelae.
    Neurotoxicology, 2006, Volume: 27, Issue:3

    Topics: Adult; Globus Pallidus; Humans; Magnetic Resonance Imaging; Male; Manganese; Neurologic Examination; Neuropsychological Tests; Occupational Diseases; Parkinsonian Disorders; Welding

2006
Dopamine transporter SPECT of a liver cirrhotic with atypical parkinsonism.
    Industrial health, 2007, Volume: 45, Issue:3

    Topics: Adult; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Globus Pallidus; Humans; Liver Cirrhosis; Male; Manganese; Parkinsonian Disorders; Tomography, Emission-Computed, Single-Photon

2007
High prevalence of Parkinsonian disorders associated to manganese exposure in the vicinities of ferroalloy industries.
    American journal of industrial medicine, 2007, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dust; Environmental Exposure; Female; Humans; Industry; Italy; Male; Manganese; Metallurgy; Middle Aged; Parkinsonian Disorders; Population Surveillance; Prevalence

2007
A synaptic mechanism underlying the behavioral abnormalities induced by manganese intoxication.
    Neurobiology of disease, 2001, Volume: 8, Issue:3

    Topics: Animals; Basal Ganglia; Behavior, Animal; Brain Chemistry; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Liver; Male; Manganese; Manganese Poisoning; Maze Learning; Motor Activity; Neuronal Plasticity; Neurons; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Dopamine D2; Substantia Nigra; Synapses; Synaptic Transmission

2001
Persistence of mild parkinsonism 4 months after liver transplantation in patients with preoperative minimal hepatic encephalopathy: a study on neuroradiological and blood manganese changes.
    Transplant international : official journal of the European Society for Organ Transplantation, 2002, Volume: 15, Issue:4

    Topics: Adult; Aged; Female; Hepatic Encephalopathy; Humans; Liver Transplantation; Magnetic Resonance Imaging; Male; Manganese; Middle Aged; Parkinsonian Disorders; Postoperative Complications; Retrospective Studies

2002