manganese has been researched along with Parkinson Disease in 128 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (15.63) | 18.7374 |
| 1990's | 11 (8.59) | 18.2507 |
| 2000's | 26 (20.31) | 29.6817 |
| 2010's | 58 (45.31) | 24.3611 |
| 2020's | 13 (10.16) | 2.80 |
| Authors | Studies |
|---|---|
| Barral, S; Budinger, D; Kurian, MA; Soo, AKS | 1 |
| Abbas, AN; Abd-Elhaleim El Azazy, MK; Abdel Hady, MMM; Abu-Elfotuh, K; Alahmre, ATS; Ali, AA; Awny, MM; El-Sisi, AM; Elewa, MAF; Hamdan, AME; Hassan, FAM; Kamal, MM; Khalil, MG; Masoud, RAE; Othman, M; Wahid, A | 1 |
| Hatanaka, Y; Ikuno, M; Isa, K; Isa, T; Murayama, S; Okuda, S; Onoe, H; Sawamura, M; Takahashi, R; Tsukada, H; Uemura, N; Yamakado, H | 1 |
| Anantharam, V; Bargues-Carot, A; Huang, M; Jin, H; Kanthasamy, A; Kanthasamy, AG; Riaz, Z; Wickham, H; Zenitsky, G | 1 |
| Blume, B; Hayen, H; Helmer, PO; Michalke, B; Schmitt-Kopplin, P; Schwantes, V; Witting, M | 1 |
| Abayomi, OA; Abayomi, TA; Arogundade, TT; Bayo-Olugbami, AA; Enaibe, BU; Ilesanmi, DO; Keji, ST; Lewu, SF; Obembe, OO; Tokunbo, OS | 1 |
| Chen, M; Deng, P; Lu, M; Mei, X; Pi, H; Wang, X; Wu, L; Yang, L; Yu, Z; Zhou, C; Zhou, Z | 1 |
| Lucchini, R; Tieu, K | 1 |
| Doroszkiewicz, J; Farhan, JA; Mroczko, B; Mroczko, J; Perkowski, M; Winkel, I | 1 |
| Liu, JY; Pradhan, SH; Sayes, CM | 1 |
| Dziki, KM; Kim, A; Monteiro, MJ; Ugolino, J; Vogel, BE; Wu, JJ | 1 |
| Aschner, M; Bowman, AB; Harrison, FE; Ijomone, OM; Lee, E; Martins, AC; Morcillo, P; Venkataramani, V | 1 |
| Ajsuvakova, OP; Aschner, M; Danilov, AB; Michalke, B; Pilipovich, AA; Skalnaya, AA; Skalnaya, MG; Skalny, AV; Tinkov, AA; Willkommen, D | 1 |
| Gonzalez-Alvarez, MA; Hernandez-Bonilla, D; Plascencia-Alvarez, NI; Riojas-Rodriguez, H; Rosselli, D | 1 |
| Betharia, S; Gadde, R; Gugnani, KS; Kulkarni, N; Vu, N; Yoo, C; Zaveri, R | 1 |
| Bowman, AB; Bryan, MR | 1 |
| Ball, HJ; Double, KL; Genoud, S; Gunn, AP; Halliday, GM; Hare, DJ; Lewis, SJG; Roberts, BR | 1 |
| Mohandas, G; Rajini, PS; Rao, SV | 1 |
| Bafana, A; Chakrabarti, T; Daiwile, AP; Krishnamurthi, K; Naoghare, PK; Parmar, D; Sivanesan, S; Stöger, R; Tarale, P | 1 |
| Federico, A; Optican, LM; Pretegiani, E; Rosini, F; Rufa, A | 1 |
| Du, K; Liu, MY; Pan, YZ; Wei, MJ; Zhong, X | 1 |
| Gazzaz, M; Lucio, M; Michalke, B; Schmitt-Kopplin, P; Schroeter, M; Sigaroudi, A; Willkommen, D | 1 |
| Alam, SM; Beltramini, M; Biosa, A; Bisaglia, M; Bubacco, L; Filograna, R; Sanchez-Martinez, A; Terriente-Felix, A; Whitworth, AJ | 1 |
| Aschner, M; Csoka, AB; Getachew, B; Tizabi, Y | 1 |
| Aschner, M; Ponzoni, S; Roth, J | 1 |
| Ceccatelli, S | 1 |
| Cheng, SY; Lin, Y; Maynard, A; Williams, CA | 1 |
| Brus, R; Kostrzewa, RM; Malinowska-Borowska, J; Nowak, D; Nowak, P; Szkilnik, R; Waliczek, M | 1 |
| Aschner, M; Bornhorst, J; Bowman, A; Brinkhaus, SG; Caldwell, GA; Caldwell, KA; Chakraborty, S; Karst, U; Knight, AL; Lohren, H; Meyer, S; Schwerdtle, T | 1 |
| Baum, J; Minetti, CA; Moriarty, GM; Remeta, DP | 1 |
| Benazzouz, A; Bouabid, S; De Deurwaerdère, P; Delaville, C; Lakhdar-Ghazal, N | 1 |
| Aaseth, J; Dusek, P; Flaten, TP; Litwin, T; Roos, PM; Schneider, SA | 1 |
| Borgohain, R; Devi, YP; Kumudini, N; Kutala, VK; Mridula, R; Naushad, SM; Uma, A | 1 |
| Andersen, JK; Angeli, S; Barhydt, T; Jacobs, R; Killilea, DW; Lithgow, GJ | 1 |
| Fukushima, T; Hayakawa, T; Hidaka, T; Kakamu, T; Kanda, H; Kumagai, T; Luo, Y; Mori, Y; Song, J; Tan, X; Tsuji, M; Wang, P | 1 |
| Aboud, AA; Bowman, AB; Erikson, KM; Ess, KC; Han, B; Hedera, P; Hong, CC; Kumar, KK; Neely, MD; Tidball, AM | 1 |
| Alavian-Ghavanini, A; Broeskamp, F; Büttner, S; Carmona-Gutierrez, D; Eisenberg, T; Habernig, L; Kroemer, G; Madeo, F; Markaki, M; Michael, E; Sigrist, SJ; Sommer, C; Tavernarakis, N | 1 |
| Aschner, M; Bornhorst, J; Bowman, AB; Chen, P; DeWitt, MR; Mukhopadhyay, S; Soares, FA | 1 |
| Aschner, M; Bowman, AB; Caito, SW; Horning, KJ; Tipps, KG | 1 |
| Aschner, M; Bowman, AB; Chakraborty, S; Chen, P; Lee, E; Mukhopadhyay, S; Paoliello, MM | 1 |
| Agostinis, P; Baekelandt, V; Eggermont, J; Günther Pomorski, T; Hermans, D; Holemans, T; Kemmer, GC; Martin, S; Palmgren, M; Sørensen, DM; Van den Haute, C; van Veen, S; Vangheluwe, P; Wuytack, F | 1 |
| Gumienna-Kontecka, E; Medici, S; Ostrowska, M; Peana, M; Remelli, M; Zoroddu, MA | 1 |
| Beltramini, M; Bisaglia, M; Bubacco, L; Casella, L; Ferrari, E; Filograna, R; Godena, VK; Sanchez-Martinez, A; Whitworth, AJ | 1 |
| Bade, AN; Boska, MD; Dong, J; Gendelman, HE; Liu, Y; Mosley, RL; Olson, KE; Schutt, CR; Shandler, SJ | 1 |
| Aschner, M; Avila, DS; Bowman, AB; Carvalho, F; Chen, P; Peres, TV; Schettinger, MR | 1 |
| Bafana, A; Chakrabarti, T; Daiwile, AP; Kannan, K; Naoghare, PK; Parmar, D; Sivanesan, S; Stöger, R; Tarale, P | 1 |
| Chen, G; Li, J; Liu, JP; Lu, Y; Wang, L | 1 |
| Fitzgerald, E; Ratner, MH | 1 |
| Flynn, MR; Susi, P | 1 |
| Caldwell, GA; Caldwell, KA; Chesi, A; Cooper, AA; Geddie, ML; Gitler, AD; Hamamichi, S; Hill, KJ; Lindquist, S; Rochet, JC; Strathearn, KE | 1 |
| Aschner, M; Au, C; Benedetto, A | 1 |
| Levora, J; Nass, R; Settivari, R | 1 |
| Becker, JS; Depboylu, C; Höglinger, GU; Matusch, A; Palm, C; Schäfer, MK; Wu, B | 1 |
| Fukushima, T; Kanda, H; Luo, Y; Tan, X | 1 |
| Feng, J; Garrick, M; Paradkar, PN; Roth, JA; Singleton, S | 1 |
| Antonini, JM; Chapman, RS; Chen, BT; Ghio, AJ; Jefferson, AM; Lin, GX; Roberts, JR; Soukup, JM; Sriram, K | 1 |
| Guilarte, TR | 1 |
| Walter, U | 1 |
| Antonini, JM; Castranova, V; Ghio, AJ; Hayashi, Y; Jefferson, AM; Krajnak, KM; Lin, GX; Munson, AE; Reynolds, SH; Roberts, JR; Soukup, JM; Sriram, K; Wirth, O | 1 |
| Aschner, M; Au, C; Avila, DS; Benedetto, A; Milatovic, D | 1 |
| Chimedregzen, U; Kagawa, Y; Kaneko, Y; Kawabata, T; Komatsu, F; Otgon, J; Purvee, B | 1 |
| Covy, JP; Giasson, BI | 1 |
| Nausieda, PA; Reimer, D; Sanchez-Ramos, J; Sullivan, K; Zesiewicz, T | 1 |
| Aschner, M; Jiang, H; Lee, E; Sidoryk-Węgrzynowicz, M; Yin, Z | 1 |
| Delogu, LG; Medici, S; Peana, M; Zoroddu, MA | 1 |
| Birke, AM; Crippin, JS; Criswell, SR; Flores, HP; Moerlein, SM; Perlmutter, JS; Racette, BA; Videen, TO | 1 |
| Chesi, A; Cooper, AA; Fang, X; Gitler, AD; Kilaru, A | 1 |
| Belluzzi, E; Beltramini, M; Bisaglia, M; Bubacco, L; Lazzarini, E; Tabares, LC | 1 |
| Abdalian, R; Allard, JP; Fernandes, G; Saqui, O | 1 |
| Borenstein, AR; Mortimer, JA; Nelson, LM | 1 |
| Cellier, MF | 1 |
| Bähr, M; Barski, E; Dučić, T; Koch, JC; Lingor, P; Salome, M | 1 |
| Benke, S; Broeskamp, F; Büttner, S; Callewaert, G; Carmona-Gutierrez, D; D'hooge, P; Eisenberg, T; Faes, L; Franssens, V; Freudenberger, P; Ghillebert, R; Habernig, L; Harger, A; Kourtis, N; Kroemer, G; Madeo, F; Pieber, TR; Reichelt, WN; Ruli, D; Sigrist, SJ; Tavernarakis, N; Winderickx, J | 1 |
| Delogu, LG; Medici, S; Peana, M; Remelli, M; Zoroddu, MA | 1 |
| Aschner, M; Sidoryk-Wegrzynowicz, M | 1 |
| Chung, HK; Jeon, B; Kim, HK; Kim, JM; Kim, JW; Kim, Y; Lee, CR; Lee, DS; Lee, JH; Yang, SO; Yoo, CI | 1 |
| Checkoway, H; Franklin, GM; Longstreth, WT; Powers, KM; Smith-Weller, T; Swanson, PD | 1 |
| Chu, NS; Huang, CC; Lu, CS; Weng, YH; Yen, TC | 1 |
| Brooks, R | 1 |
| Olanow, CW | 1 |
| Andersen, JK; Doctrow, SR; Peng, J; Stevenson, FF | 1 |
| Jankovic, J | 1 |
| Amano, R; Ishida, Y; Kawai, K; Tarohda, T; Yamamoto, M | 1 |
| Gaeta, A; Hider, RC | 1 |
| Blot, WJ; Brandt, L; Ekbom, A; Fored, CM; Fryzek, JP; McLaughlin, JK; Nise, G; Sjögren, B | 1 |
| Kim, DH; Kim, JW; Kim, Y; Park, J; Shin, YC; Sim, CS; Yi, Y; Yoo, CI | 1 |
| Hirata, Y; Kiuchi, K; Meguro, T | 1 |
| Gula, MJ; Marsh, GM | 1 |
| Yokel, RA | 1 |
| Finkelstein, MM; Jerrett, M | 1 |
| Ben-Hur, T; Bergman, H; Goelman, G; Pelled, G | 1 |
| Case, LF; Fields, T; Graham, L; Kanabrocki, EL; Kaplan, E; Miller, EB; Oester, YT | 1 |
| Barbeau, A | 1 |
| Atadzhanov, M | 1 |
| Mehnert, E | 1 |
| Damsgaard, E; Heydorn, K; Larsen, NA; Pakkenberg, H; Wold, S | 1 |
| Carolei, A; Hernandez, MC; Margotta, V; Palladini, G | 1 |
| Aguilar, MV; Arrieta, FJ; Ayuso-Peralta, L; Cabrera-Valdivia, F; García-Albea, E; Jiménez-Jiménez, FJ; Jorge-Santamaría, A; Molina, JA; Rabasa, M; Vázquez, A | 1 |
| Bélanger, S; Beuter, A; Carrière, L; de Geoffroy, A; Gauthier, S; Mergler, D; Sreekumar, J; Varghese, L | 1 |
| Calne, DB; Chu, NS; Huang, CC; Lu, CS; Olanow, W | 1 |
| Brown, GG; Gorell, JM; Johnson, CC; Kortsha, GX; Peterson, EL; Richardson, RJ; Rybicki, BA | 1 |
| Dryhurst, G; Shen, XM | 1 |
| Aguilar, MV; de Bustos, F; González-Muñoz, MJ; Jiménez-Jiménez, FJ; Martínez-Para, MC; Martínez-Salio, A; Mateos-Vega, CJ; Meseguer, I; Molina, JA; Ortí-Pareja, M; Zurdo, M | 1 |
| Friedman, MB; Snyder, RD | 1 |
| Chen, WH; Kao, HJ; Liu, JS | 1 |
| Bergamasco, B; Chiesa, M; Digilio, G; Fasano, M; Giraudo, S; Lopiano, L; Torre, E | 1 |
| Aschner, M | 1 |
| Delogu, MR; Desole, MS; Enrico, P; Esposito, G; Grella, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, PA | 1 |
| McGee-Minnich, L; Mink, JW; Moerlein, SM; Perlmutter, JS; Racette, BA; Videen, TO | 1 |
| Arakawa, R; Kumamoto, T; Sato, K; Tsuda, T; Ueyama, H | 1 |
| Jenner, P; Kunikowska, G | 1 |
| Duckett, S; Galle, P; Kradin, R | 1 |
| Barbeau, A; Cloutier, T; Inoué, N | 1 |
| Dexter, DT; Jenner, P; Marsden, CD; Schapira, AH | 1 |
| Camerlingo, M; Casto, L; Ferraro, B; Gazzaniga, GC; Mamoli, A; Viscardi, M | 1 |
| Feldman, RG | 1 |
| Brooks, DJ; Gadian, D; Luthert, P; Marsden, CD | 1 |
| Blake, DR; Gutteridge, JM; Hall, M; Lunec, J; Pall, HS; Taylor, A; Williams, AC | 1 |
| McGeer, PL | 1 |
| Cotzias, GC; Gellene, R; Papavasiliou, PS | 1 |
| Cotzias, GC; Miller, ST; Papavasiliou, PS | 1 |
| Dugan, T; Ruhf, RC; Smyth, LT; Whitman, NE | 1 |
| Nakajima, T | 1 |
| Cotzias, GC; Schiffer, LM; Van Woert, MH | 1 |
| Cotzias, GC | 2 |
| Mindadse, AA; Tschikowani, TI | 1 |
| Abrams, BM; Elizan, TS; Hirano, A; Kurland, LT; Need, RL; Van Nuis, C | 1 |
32 review(s) available for manganese and Parkinson Disease
| Article | Year |
|---|---|
The role of manganese dysregulation in neurological disease: emerging evidence.
Topics: Brain; Humans; Manganese; Manganese Poisoning; Neurodegenerative Diseases; Parkinson Disease | 2021 |
Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson's Disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; DDT; Dieldrin; Herbicides; Humans; Manganese; Mitochondria; Neuroinflammatory Diseases; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Parkinson Disease; Pesticides; Risk Factors; Rotenone; Trichloroethanes; Vanadium | 2022 |
Manganese-Induced Parkinsonism: Evidence from Epidemiological and Experimental Studies.
Topics: Genetic Predisposition to Disease; Humans; Manganese; Parkinson Disease; Parkinsonian Disorders | 2023 |
Common and Trace Metals in Alzheimer's and Parkinson's Diseases.
Topics: Alzheimer Disease; Copper; Humans; Iron; Manganese; Metals; Neurodegenerative Diseases; Parkinson Disease; Trace Elements; Zinc | 2023 |
New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease.
Topics: Alzheimer Disease; Animals; Humans; Mammals; Manganese; Neurotoxins; Parkinson Disease | 2019 |
Environmental and occupational exposure to metals (manganese, mercury, iron) and Parkinson's disease in low and middle-income countries: a narrative review.
Topics: Cross-Sectional Studies; Developing Countries; Environmental Exposure; Humans; Iron; Manganese; Mercury; Metals, Heavy; Occupational Exposure; Parkinson Disease | 2022 |
Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Autophagy; Brain; Disease Models, Animal; Humans; Huntingtin Protein; Huntington Disease; Insulin; Manganese; Mitochondria; Neostriatum; Neural Stem Cells; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Signal Transduction; Somatomedins | 2017 |
Association of circulating manganese levels with Parkinson's disease: A meta-analysis.
Topics: Aged; China; Female; Homeostasis; Humans; Ions; Male; Manganese; Middle Aged; Parkinson Disease; Risk Factors | 2018 |
Mechanisms of neurotoxicity and implications for neurological disorders.
Topics: Anti-HIV Agents; Central Nervous System Stimulants; Congresses as Topic; Hazardous Substances; Humans; Manganese; Methamphetamine; Nervous System Diseases; Neurotoxicity Syndromes; Neurotoxins; Parkinson Disease; Receptors, Dopamine; Risk Factors; Trace Elements | 2013 |
The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases.
Topics: Animals; Brain; Copper; Disease Models, Animal; Environmental Exposure; Hepatolenticular Degeneration; Homeostasis; Humans; Iron; Manganese; Parkinson Disease | 2015 |
Manganese Is Essential for Neuronal Health.
Topics: Arginase; Bile; Blood-Brain Barrier; Brain; Enzyme Activation; Glutamate-Ammonia Ligase; Health Status; Homeostasis; Humans; Huntington Disease; Intestinal Absorption; Manganese; Nervous System Diseases; Neurons; Parkinson Disease | 2015 |
Manganese homeostasis in the nervous system.
Topics: Animals; Homeostasis; Humans; Manganese; Manganese Poisoning; Membrane Transport Proteins; Neurodegenerative Diseases; Parkinson Disease; Protein Transport | 2015 |
Manganese-Enhanced Magnetic Resonance Imaging for Detection of Vasoactive Intestinal Peptide Receptor 2 Agonist Therapy in a Model of Parkinson's Disease.
Topics: Animals; Brain; Dopaminergic Neurons; Image Enhancement; Magnetic Resonance Imaging; Male; Manganese; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Oligopeptides; Parkinson Disease; Parkinsonian Disorders; Protein-Tyrosine Kinases; Receptors, Vasoactive Intestinal Peptide, Type II | 2016 |
"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies".
Topics: Animals; Brain; Cognition Disorders; Food; Humans; Manganese; Manganese Poisoning; Motor Skills Disorders; Neuroprotective Agents; Parkinson Disease | 2016 |
Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism.
Topics: alpha-Synuclein; Animals; Disruptive, Impulse Control, and Conduct Disorders; Humans; Intracellular Membranes; Lewy Bodies; Lysosomes; Manganese; Neurons; Parkinson Disease; Protein Transport; Proton-Translocating ATPases | 2017 |
Neurological risks associated with manganese exposure from welding operations--a literature review.
Topics: Diagnosis, Differential; Environmental Pollutants; Humans; Manganese; Neurotoxicity Syndromes; Occupational Exposure; Parkinson Disease; Risk Assessment; Welding | 2009 |
Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's disease.
Topics: Amino Acid Sequence; Animals; Dopamine; Humans; Manganese; Molecular Chaperones; Molecular Sequence Data; Parkinson Disease | 2009 |
Manganese and Parkinson's disease: a critical review and new findings.
Topics: Animals; Basal Ganglia; Diagnosis, Differential; Environmental Exposure; Humans; Manganese; Manganese Poisoning; Nerve Degeneration; Parkinson Disease; Parkinson Disease, Secondary; Primates | 2010 |
Transcranial sonography in brain disorders with trace metal accumulation.
Topics: Copper; Dystonia; Hepatolenticular Degeneration; Humans; Iron; Manganese; Metals; Parkinson Disease; Trace Elements; Ultrasonography | 2010 |
α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease.
Topics: Aging; alpha-Synuclein; Amino Acid Sequence; Animals; Cell Membrane; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Manganese; Molecular Sequence Data; Mutation, Missense; Parkinson Disease; Protein Serine-Threonine Kinases | 2011 |
Associations of welding and manganese exposure with Parkinson disease: review and meta-analysis.
Topics: Humans; Manganese; Occupational Exposure; Parkinson Disease; Welding | 2012 |
Manganese toxicity in the central nervous system: the glutamine/glutamate-γ-aminobutyric acid cycle.
Topics: Central Nervous System; Dementia; Evidence-Based Medicine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Manganese; Parkinson Disease | 2013 |
Manganese-induced parkinsonism and Parkinson's disease.
Topics: Animals; Brain; Humans; Magnetic Resonance Imaging; Manganese; Manganese Poisoning; Parkinson Disease; Parkinsonian Disorders; Tomography, Emission-Computed, Single-Photon | 2004 |
Searching for a relationship between manganese and welding and Parkinson's disease.
Topics: Age of Onset; Brain; Cohort Studies; Cross-Sectional Studies; Disease Progression; Humans; Manganese; Manganese Poisoning; Occupational Exposure; Parkinson Disease; Risk Factors; Welding | 2005 |
The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Chelating Agents; Copper; Humans; Ions; Iron; Manganese; Metals; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Prion Diseases; Prions; Proteins | 2005 |
Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration.
Topics: Aluminum; Alzheimer Disease; Basement Membrane; Blood-Brain Barrier; Brain; Copper; Humans; Iron; Manganese; Membrane Transport Proteins; Mercury; Nerve Degeneration; Parkinson Disease; Zinc | 2006 |
[Modeling parkinsonism (review)].
Topics: Aluminum; Animals; Carbachol; Cats; Caudate Nucleus; Chlorides; Chlorpromazine; Disease Models, Animal; Globus Pallidus; Humans; Hydroxydopamines; Manganese; Manganese Compounds; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Putamen; Rabbits; Rats; Red Nucleus; Reserpine; Substantia Nigra; Syndrome; Tetanus Toxin; Thalamus; Tungsten; Tungsten Compounds | 1982 |
Manganism and idiopathic parkinsonism: similarities and differences.
Topics: Brain; Humans; Manganese; Manganese Poisoning; Movement Disorders; Nervous System Diseases; Parkinson Disease; Parkinson Disease, Secondary | 1994 |
Manganese: brain transport and emerging research needs.
Topics: Animals; Binding Sites; Biological Transport; Brain; Environmental Exposure; Humans; Inhalation Exposure; Kinetics; Manganese; Motor Vehicles; Parkinson Disease; Rats; Risk Assessment | 2000 |
[A case of welder presenting with parkinsonism after chronic manganese exposure].
Topics: Brain; Humans; Magnetic Resonance Imaging; Male; Manganese; Middle Aged; Occupational Exposure; Parkinson Disease; Parkinson Disease, Secondary; Welding | 2000 |
Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group.
Topics: Basal Ganglia Diseases; Copper; Ferritins; Humans; Iron; Manganese; Parkinson Disease; Trace Elements; Zinc | 1992 |
[Biochemical aspect of Parkinson's disease].
Topics: Acetylcholine; Animals; Atropine; Basement Membrane; Brain; Carbachol; Catecholamines; Dihydroxyphenylalanine; Electrocoagulation; Humans; Manganese; Melanins; Neurophysiology; Parkinson Disease | 1968 |
3 trial(s) available for manganese and Parkinson Disease
| Article | Year |
|---|---|
Occupational exposures to metals as risk factors for Parkinson's disease.
Topics: Aged; Aged, 80 and over; Copper; Female; Humans; Iron; Lead; Male; Manganese; Mercury; Metals; Middle Aged; Occupational Exposure; Odds Ratio; Parkinson Disease; Risk Factors; Surveys and Questionnaires; Zinc | 1997 |
Modification of Parkinsonism--chronic treatment with L-dopa.
Topics: Adult; Aged; Agranulocytosis; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Urea Nitrogen; Blood-Brain Barrier; Chronic Disease; Dihydroxyphenylalanine; Dopamine; Feeding and Eating Disorders; Female; Humans; Huntington Disease; Male; Manganese; Mental Processes; Methyldopa; Middle Aged; Movement Disorders; Nausea; Neurologic Manifestations; Parkinson Disease; Phenylacetates; Placebos; Thyroid Function Tests; Tyrosine; Vomiting | 1969 |
Aromatic amino acids and modification of parkinsonism.
Topics: Adult; Aged; Agranulocytosis; Bone Marrow Examination; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Male; Manganese; Melanocyte-Stimulating Hormones; Middle Aged; Parkinson Disease; Phenylalanine; Placebos | 1967 |
93 other study(ies) available for manganese and Parkinson Disease
| Article | Year |
|---|---|
Evaluating the neuroprotective activities of vinpocetine, punicalagin, niacin and vitamin E against behavioural and motor disabilities of manganese-induced Parkinson's disease in Sprague Dawley rats.
Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents; Antioxidants; Glycogen Synthase Kinase 3 beta; Hydrolyzable Tannins; Manganese; Neuroprotection; Neuroprotective Agents; Niacin; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Vinca Alkaloids; Vitamin E | 2022 |
Lewy Body Disease Primate Model with α-Synuclein Propagation from the Olfactory Bulb.
Topics: alpha-Synuclein; Animals; Callithrix; Deoxyglucose; Glucose; Lewy Body Disease; Manganese; Olfactory Bulb; Parkinson Disease | 2022 |
Lipidomic and Metallomic Alteration of
Topics: Animals; Caenorhabditis elegans; Dopaminergic Neurons; Iron; Lipidomics; Manganese; Metals; Neurodegenerative Diseases; Parkinson Disease; Zinc | 2023 |
African walnut (Tetracarpidium conophorum) extract upregulates glucocerebrosidase activity and circumvents Parkinsonian changes in the Hippocampus via the activation of heatshock proteins.
Topics: alpha-Synuclein; Animals; Glucosylceramidase; Heat-Shock Proteins; Hippocampus; Juglans; Male; Manganese; Parkinson Disease; Plant Extracts; Rats | 2023 |
Manganese overexposure induces Parkinson-like symptoms, altered lipid signature and oxidative stress in C57BL/6 J mouse.
Topics: Animals; Humans; Lipids; Male; Manganese; Mice; Mice, Inbred C57BL; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders | 2023 |
Evaluating Manganese, Zinc, and Copper Metal Toxicity on SH-SY5Y Cells in Establishing an Idiopathic Parkinson's Disease Model.
Topics: Cell Line, Tumor; Copper; Dopamine; Heavy Metal Poisoning; Humans; Manganese; Metals; Neuroblastoma; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Zinc | 2023 |
Overexpression of human Atp13a2Isoform-1 protein protects cells against manganese and starvation-induced toxicity.
Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cell Death; Dopaminergic Neurons; HeLa Cells; Humans; Manganese; Parkinson Disease; Protective Agents; Protein Isoforms; Proton-Translocating ATPases; Starvation | 2019 |
Assessment of copper, iron, zinc and manganese status and speciation in patients with Parkinson's disease: A pilot study.
Topics: Aged; Copper; Female; Hair; Humans; Iron; Male; Manganese; Middle Aged; Parkinson Disease; Pilot Projects; Zinc | 2020 |
Neuroprotective effects of disubstituted dithiolethione ACDT against manganese-induced toxicity in SH-SY5Y cells.
Topics: Cell Line, Tumor; Encephalomyelitis, Autoimmune, Experimental; Esters; Humans; Manganese; Manganese Poisoning; Neuroprotective Agents; Parkinson Disease; Reactive Oxygen Species; Sulfhydryl Compounds | 2021 |
Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain.
Topics: Adult; Aged; Aged, 80 and over; Brain; Case-Control Studies; Copper; Female; Humans; Iron; Male; Manganese; Middle Aged; Parkinson Disease; Subcellular Fractions; Zinc | 2017 |
Whey protein isolate enrichment attenuates manganese-induced oxidative stress and neurotoxicity in Drosophila melanogaster: Relevance to Parkinson's disease.
Topics: Age Factors; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Dopamine; Drosophila melanogaster; Female; Glutathione; Humans; Locomotion; Male; Manganese; Mitochondria; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Protein Carbonylation; Sex Factors; Whey Proteins | 2017 |
Manganese exposure: Linking down-regulation of miRNA-7 and miRNA-433 with α-synuclein overexpression and risk of idiopathic Parkinson's disease.
Topics: alpha-Synuclein; Cell Line, Tumor; Computer Simulation; Down-Regulation; Gene Expression Regulation; Humans; Manganese; MicroRNAs; Models, Biological; Neurons; Oligonucleotide Array Sequence Analysis; Parkinson Disease; Polymerase Chain Reaction; Up-Regulation | 2018 |
Eye movements in genetic parkinsonisms affecting the α-synuclein, PARK9, and manganese network.
Topics: Adult; Aged; alpha-Synuclein; Eye Movements; Female; Humans; Male; Manganese; Middle Aged; Parkinson Disease; Proton-Translocating ATPases; Young Adult | 2017 |
Species fractionation in a case-control study concerning Parkinson's disease: Cu-amino acids discriminate CSF of PD from controls.
Topics: Aged; Amino Acids; Case-Control Studies; Chromatography, Gel; Copper; Female; Humans; Iron; Male; Manganese; Mass Spectrometry; Middle Aged; Parkinson Disease; Zinc | 2018 |
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss.
Topics: Blotting, Western; HEK293 Cells; HeLa Cells; Humans; Manganese; Organometallic Compounds; Oxidative Stress; Parkinson Disease; Protein Kinases; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitin-Protein Ligases | 2018 |
Nicotine protects against manganese and iron-induced toxicity in SH-SY5Y cells: Implication for Parkinson's disease.
Topics: Cell Line, Tumor; Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; Humans; Iron; Manganese; Nicotine; Parkinson Disease | 2019 |
Manganese homeostasis and transport.
Topics: Homeostasis; Humans; Manganese; Manganese Poisoning; Mitochondria; Parkinson Disease | 2013 |
Involvement of NF kappa B in potentiated effect of Mn-containing dithiocarbamates on MPP(+) induced cell death.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Death; Cell Survival; Ditiocarb; Luciferases; Maneb; Manganese; NF-kappa B; Parkinson Disease; PC12 Cells; Peptides; Rats; Response Elements; Signal Transduction; Zineb | 2013 |
Ontogenetic manganese exposure with perinatal 6-OHDA lesioning alters behavioral responses of rats to dopamine D₁ and D2 agonist treatments.
Topics: Animals; Behavior, Animal; Desipramine; Dopamine; Dopamine Agonists; Exploratory Behavior; Female; Homovanillic Acid; Manganese; Maternal-Fetal Exchange; Motor Activity; Neostriatum; Oxidopamine; Pargyline; Parkinson Disease; Pregnancy; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2014 |
The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.
Topics: Aldehyde Oxidoreductases; alpha-Synuclein; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Gene Deletion; Gene Expression Regulation; Humans; Manganese; Mutation; Oxidative Stress; Parkinson Disease; Protein Serine-Threonine Kinases; Ubiquitin-Protein Ligases | 2014 |
A revised picture of the Cu(II)-α-synuclein complex: the role of N-terminal acetylation.
Topics: Acetylation; alpha-Synuclein; Amyloid; Binding Sites; Circular Dichroism; Copper; Humans; Manganese; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease | 2014 |
Manganese-induced atypical parkinsonism is associated with altered Basal Ganglia activity and changes in tissue levels of monoamines in the rat.
Topics: Animals; Anxiety; Basal Ganglia; Body Weight; Dopamine; Electrophysiology; Globus Pallidus; Locomotion; Male; Manganese; Neurons; Norepinephrine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Serotonin; Subthalamic Nucleus; Synaptic Transmission | 2014 |
Association of Parkinson's disease with altered serum levels of lead and transition metals among South Indian subjects.
Topics: Case-Control Studies; Copper; Female; Humans; India; Iron; Lead; Male; Malondialdehyde; Manganese; Mass Spectrometry; Middle Aged; Oxidative Stress; Parkinson Disease; Transition Elements | 2014 |
Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Homeostasis; Iron; Manganese; Parkinson Disease; Protein Aggregates; Protein Aggregation, Pathological; Unfolded Protein Response | 2014 |
Correlations among heavy metals in blood and urine and their relations to depressive symptoms in Parkinson's disease patients.
Topics: Aged; Case-Control Studies; Depression; Female; Humans; Iron; Male; Manganese; Metals, Heavy; Middle Aged; Parkinson Disease; Zinc | 2014 |
PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper.
Topics: Adult; Cadmium; Cell Line; Copper; Genetic Predisposition to Disease; Humans; Induced Pluripotent Stem Cells; Male; Manganese; Membrane Potential, Mitochondrial; Methylmercury Compounds; Mitochondria; Mutation; Neural Stem Cells; Parkinson Disease; Risk Factors; Ubiquitin-Protein Ligases | 2015 |
Spermidine protects against α-synuclein neurotoxicity.
Topics: alpha-Synuclein; Animals; Autophagy; Caenorhabditis elegans; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Humans; Manganese; Motor Activity; Parkinson Disease; Protective Agents; Spermidine | 2014 |
Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease.
Topics: Aging; Aldehyde Oxidoreductases; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopaminergic Neurons; Forkhead Transcription Factors; Gene Deletion; Green Fluorescent Proteins; Longevity; Manganese; Models, Biological; Models, Genetic; Movement; Parkinson Disease; Phenotype; Signal Transduction; Survival Analysis | 2015 |
A lipid switch unlocks Parkinson's disease-associated ATP13A2.
Topics: Amino Acid Sequence; Cell Line; Cell Membrane; Cytosol; Endosomes; Green Fluorescent Proteins; HeLa Cells; Humans; Lipids; Lysosomes; Manganese; Mitochondria; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutation; Parkinson Disease; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphorylation; Protein Binding; Proton-Translocating ATPases; Structural Homology, Protein; Zinc | 2015 |
Manganism and Parkinson's disease: Mn(II) and Zn(II) interaction with a 30-amino acid fragment.
Topics: Coordination Complexes; Electron Spin Resonance Spectroscopy; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Manganese; Parkinson Disease; Peptides; Potentiometry; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Zinc | 2016 |
Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE.
Topics: Animals; Biomimetic Materials; Cell Line, Tumor; Drosophila melanogaster; Humans; Manganese; Models, Biological; Organometallic Compounds; Oxidative Stress; Paraquat; Parkinson Disease; Superoxide Dismutase | 2016 |
Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson's disease-associated genes.
Topics: Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Manganese; Neuroblastoma; Parkinson Disease; Protein Kinases; Ubiquitin-Protein Ligases | 2017 |
Understanding of the role of manganese in parkinsonism and Parkinson disease.
Topics: Humans; Manganese; Manganese Poisoning; Parkinson Disease; Parkinson Disease, Secondary; Parkinsonian Disorders | 2017 |
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity.
Topics: alpha-Synuclein; Animals; Caenorhabditis elegans; Cells, Cultured; Conserved Sequence; Drug Resistance; Epistasis, Genetic; Gene Regulatory Networks; Manganese; Mutation; Neurons; Parkinson Disease; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tissue Distribution | 2009 |
The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabditis elegans models of manganism and parkinson disease.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cation Transport Proteins; Cell Death; Disease Models, Animal; Dopamine; Humans; Iron; Manganese; Manganese Poisoning; Neurons; Parkinson Disease; Reactive Oxygen Species; Sequence Homology, Amino Acid | 2009 |
Cerebral bioimaging of Cu, Fe, Zn, and Mn in the MPTP mouse model of Parkinson's disease using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Calibration; Copper; Equipment Design; Iron; Laser Therapy; Male; Manganese; Mass Spectrometry; Metals, Heavy; Mice; Mice, Inbred C57BL; Neurotoxins; Parkinson Disease; Zinc | 2010 |
Relationship between blood levels of heavy metals and Parkinson's disease in China.
Topics: China; Diet; Female; Humans; Iron; Male; Manganese; Metals, Heavy; Middle Aged; Parkinson Disease; Photoperiod; Rural Population; Socioeconomic Factors; Time Factors; Urban Population | 2010 |
Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1.
Topics: Adult; Animals; B-Lymphocytes; Cation Transport Proteins; Cell Death; Cells, Cultured; Chlorides; Cysteine Proteinase Inhibitors; Exons; Gene Expression Regulation; Humans; Immunoprecipitation; Leupeptins; Male; Manganese; Manganese Compounds; Mice; Mice, Knockout; Mutation; Neuroblastoma; Parkinson Disease; Proteasome Endopeptidase Complex; Protein Isoforms; Transfection; Ubiquitin-Protein Ligases | 2010 |
Dopaminergic neurotoxicity following pulmonary exposure to manganese-containing welding fumes.
Topics: Animals; Dopamine; Down-Regulation; Gases; Iron; Lung; Male; Manganese; Metals; Neurotoxicity Syndromes; Occupational Exposure; Parkinson Disease; Rats; Rats, Sprague-Dawley; Steel; Welding | 2010 |
Mitochondrial dysfunction and loss of Parkinson's disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes.
Topics: Air Pollutants, Occupational; Animals; Blotting, Western; Chlorides; Inhalation Exposure; Male; Manganese; Manganese Compounds; Occupational Exposure; Parkinson Disease; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase; Ubiquitin-Protein Ligases; Welding | 2010 |
Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Extracellular Space; Female; Humans; Life Expectancy; Male; Manganese; Nerve Degeneration; Neurons; Oxidative Stress; Oxidoreductases; Parkinson Disease; Protein Transport | 2010 |
A high accumulation of hair minerals in Mongolian people: 2(nd) report; influence of manganese, iron, lead, cadmium and aluminum to oxidative stress, Parkinsonism and arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aluminum; Arthritis; Cadmium; Case-Control Studies; Child; Female; Hair; Humans; Iron; Japan; Lead; Male; Manganese; Middle Aged; Minerals; Mongolia; Oxidative Stress; Parkinson Disease; Poaceae; Prevalence; Soil; Water; Young Adult | 2011 |
Quantitative analysis of tremors in welders.
Topics: Diagnosis, Differential; Female; Humans; Male; Manganese; Middle Aged; Occupational Diseases; Parkinson Disease; Retrospective Studies; Tremor; Welding | 2011 |
15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Chromones; Cytoprotection; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Manganese; Morpholines; NF-E2-Related Factor 2; NF-kappa B; Oncogene Proteins; Oxidative Stress; Parkinson Disease; Phosphoinositide-3 Kinase Inhibitors; Prostaglandin D2; Protein Deglycase DJ-1; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcriptional Activation | 2012 |
Mn(II) and Zn(II) interactions with peptide fragments from Parkinson's disease genes.
Topics: Amino Acid Sequence; Environmental Pollutants; Humans; Manganese; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Peptide Fragments; Protein Binding; Proton-Translocating ATPases; Zinc | 2012 |
Reduced uptake of FDOPA PET in end-stage liver disease with elevated manganese levels.
Topics: Caudate Nucleus; Ceruloplasmin; Dihydroxyphenylalanine; End Stage Liver Disease; Hepatitis B; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Liver Cirrhosis, Alcoholic; Magnetic Resonance Imaging; Male; Manganese; Middle Aged; Parkinson Disease; Putamen; Radionuclide Imaging; Radiopharmaceuticals | 2012 |
The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast.
Topics: Gene Deletion; Homeostasis; Humans; Manganese; Parkinson Disease; Proton-Translocating ATPases; Saccharomyces cerevisiae | 2012 |
Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease.
Topics: Catalytic Domain; Dopamine; Enzyme Activation; Humans; Kinetics; Manganese; Mitochondria; Mutation; Parkinson Disease; Protein Binding; Reactive Oxygen Species; Superoxide Dismutase | 2012 |
Effects of manganese from a commercial multi-trace element supplement in a population sample of Canadian patients on long-term parenteral nutrition.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Attention; Brain; Canada; Cognition Disorders; Depression; Dietary Supplements; Female; Gait; Gait Disorders, Neurologic; Humans; Male; Manganese; Memory Disorders; Middle Aged; Parenteral Nutrition; Parkinson Disease; Trace Elements; Young Adult | 2013 |
Nramp: from sequence to structure and mechanism of divalent metal import.
Topics: Animals; Bacteria; Bacterial Proteins; Cation Transport Proteins; Evolution, Molecular; Ferrous Compounds; Gene Expression Regulation; Humans; Iron Overload; Manganese; Mice; Parkinson Disease; Phylogeny; Plasma Membrane Neurotransmitter Transport Proteins; Protein Structure, Tertiary; Tuberculosis | 2012 |
X-ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons.
Topics: Animals; Dopaminergic Neurons; Green Fluorescent Proteins; Iron; Manganese; Mice; Mice, Transgenic; Parkinson Disease; Primary Cell Culture; Spectrometry, X-Ray Emission | 2013 |
The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.
Topics: Acetylcysteine; alpha-Synuclein; Animals; Apoptosis; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Calcium-Transporting ATPases; Humans; Manganese; Models, Biological; Molecular Chaperones; Oxidative Stress; Parkinson Disease; Phosphorylation; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
Interaction of divalent cations with peptide fragments from Parkinson's disease genes.
Topics: Amino Acid Sequence; Cations, Divalent; Coordination Complexes; Copper; Humans; Magnetic Resonance Spectroscopy; Manganese; Parkinson Disease; Peptides; Proton-Translocating ATPases; Zinc | 2013 |
Dopamine transporter density is decreased in parkinsonian patients with a history of manganese exposure: what does it mean?
Topics: Causality; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Male; Manganese; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Occupational Exposure; Parkinson Disease; Parkinson Disease, Secondary; Tomography, Emission-Computed, Single-Photon | 2002 |
Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes.
Topics: Adult; Aged; Antioxidants; Case-Control Studies; Diet; Fats; Female; Humans; Iron, Dietary; Male; Manganese; Middle Aged; Minerals; Parkinson Disease; Risk Factors; Vitamins | 2003 |
Dopamine transporter binding in chronic manganese intoxication.
Topics: Brain; Chronic Disease; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iron; Male; Manganese; Manganese Poisoning; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Organotechnetium Compounds; Parkinson Disease; Parkinson Disease, Secondary; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Tropanes | 2003 |
Welding health update.
Topics: Asthma; Humans; Manganese; Neoplasms; Occupational Exposure; Occupational Health; Parkinson Disease; Respiratory Function Tests; United States; Welding | 2004 |
Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease.
Topics: Animals; Antioxidants; Blotting, Western; Catalase; Cells, Cultured; Dopamine; Immunohistochemistry; Male; Manganese; Manganese Compounds; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Models, Chemical; Neurons; Neuroprotective Agents; Organometallic Compounds; Oxidative Stress; Paraquat; Parkinson Disease; Rats; Salicylates; Substantia Nigra; Superoxide Dismutase; Time Factors | 2005 |
Regional distributions of manganese, iron, copper, and zinc in the brains of 6-hydroxydopamine-induced parkinsonian rats.
Topics: Adrenergic Agents; Amygdala; Animals; Copper; Globus Pallidus; Iron; Manganese; Mass Spectrometry; Oxidopamine; Parkinson Disease; Putamen; Rats; Time Factors; Tissue Distribution; Zinc | 2005 |
Parkinson's disease and other basal ganglia or movement disorders in a large nationwide cohort of Swedish welders.
Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia Diseases; Epidemiologic Methods; Humans; Male; Manganese; Middle Aged; Movement Disorders; Occupational Diseases; Occupational Exposure; Parkinson Disease; Sweden; Welding | 2006 |
A retrospective cohort study of Parkinson's disease in Korean shipbuilders.
Topics: Age of Onset; Cohort Studies; Confidence Intervals; Humans; Insurance, Physician Services; Korea; Male; Manganese; Occupational Diseases; Occupational Exposure; Occupations; Parkinson Disease; Regression, Psychology; Retrospective Studies; Risk; Welding | 2006 |
Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Caspases; Dopamine; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Manganese; MAP Kinase Signaling System; Nerve Growth Factor; Neurons; Neurotoxins; Parkinson Disease; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Reactive Oxygen Species; Receptor Protein-Tyrosine Kinases; Rotenone; Signal Transduction; Substantia Nigra | 2006 |
Employment as a welder and Parkinson disease among heavy equipment manufacturing workers.
Topics: Adult; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Female; Humans; Illinois; Male; Manganese; Middle Aged; Occupational Diseases; Occupational Exposure; Odds Ratio; Parkinson Disease; Steel; Welding | 2006 |
A study of the relationships between Parkinson's disease and markers of traffic-derived and environmental manganese air pollution in two Canadian cities.
Topics: Adult; Aged; Air Pollutants; Antiparkinson Agents; Canada; Case-Control Studies; Cities; Cohort Studies; Humans; Levodopa; Manganese; Middle Aged; Parkinson Disease; Vehicle Emissions | 2007 |
Manganese-enhanced MRI in a rat model of Parkinson's disease.
Topics: Animals; Basal Ganglia; Brain; Cell Nucleus; Disease Models, Animal; Dopamine; Magnetic Resonance Imaging; Male; Manganese; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors | 2007 |
Non-dialyzable manganese and copper levels in serum of patients with various diseases.
Topics: Carcinoma; Copper; Diabetes Mellitus; Humans; Liver Cirrhosis; Male; Manganese; Multiple Sclerosis; Myocardial Infarction; Parkinson Disease; Prostatic Neoplasms; Renal Dialysis; Uremia | 1967 |
Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias).
Topics: Animals; Basal Ganglia; Basal Ganglia Diseases; Brain Chemistry; Catecholamines; Disease Models, Animal; Humans; Levodopa; Manganese; Manganese Poisoning; Melanins; Melanocyte-Stimulating Hormones; Parkinson Disease; Substantia Nigra | 1984 |
[Diagnostic significant of manganese concentration in blood serum. Current state of knowledge].
Topics: Animals; Cattle; Clinical Laboratory Techniques; Diabetes Mellitus; Humans; Manganese; Myocardial Infarction; Parkinson Disease; Rats; Reference Standards | 1982 |
Distribution of arsenic, manganese, and selenium in the human brain in chronic renal insufficiency, Parkinson's disease, and amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Arsenic; Brain; Female; Humans; Kidney Failure, Chronic; Male; Manganese; Middle Aged; Parkinson Disease; Selenium | 1981 |
Dopamine agonist performance in Planaria after manganese treatment.
Topics: Animals; Disease Models, Animal; Dopamine; Manganese; Parkinson Disease; Planarians; Turbellaria | 1980 |
Serum and urinary manganese levels in patients with Parkinson's disease.
Topics: Activities of Daily Living; Aged; Brain; Chromium; Cobalt; Female; Humans; Lipid Peroxidation; Male; Manganese; Metabolic Clearance Rate; Parkinson Disease; Parkinson Disease, Secondary; Receptors, Dopamine; Risk Factors | 1995 |
Diadochokinesimetry: a study of patients with Parkinson's disease and manganese exposed workers.
Topics: Humans; Manganese; Middle Aged; Movement; Occupational Exposure; Parkinson Disease | 1994 |
Iron- and manganese-catalyzed autoxidation of dopamine in the presence of L-cysteine: possible insights into iron- and manganese-mediated dopaminergic neurotoxicity.
Topics: Chromatography, High Pressure Liquid; Cysteine; Dopamine; Electrochemistry; Iron; Magnetic Resonance Spectroscopy; Manganese; Oxidation-Reduction; Parkinson Disease; Spectrophotometry, Ultraviolet | 1998 |
Cerebrospinal fluid levels of transition metals in patients with Parkinson's disease.
Topics: Age of Onset; Aged; Antiparkinson Agents; Blood Proteins; Copper; Dopamine Agonists; Female; Humans; Iron; Levodopa; Male; Manganese; Metals, Heavy; Middle Aged; Nutritional Status; Parkinson Disease; Reference Values; Selegiline; Spectrophotometry, Atomic; Trace Elements; Vitamin A; Zinc | 1998 |
Enhancement of cytotoxicity and clastogenicity of l-DOPA and dopamine by manganese and copper.
Topics: Animals; Cell Division; Cell Line; Copper; Cricetinae; Cysteine; Dopamine; Glutathione; Levodopa; Lung; Manganese; Melanins; Micronucleus Tests; Mutagens; Parkinson Disease | 1998 |
Rapid progression of parkinsonism associated with an increase of blood manganese.
Topics: Aged; Aluminum; Humans; Male; Manganese; Manganese Poisoning; Parkinson Disease | 1999 |
Q-band EPR investigations of neuromelanin in control and Parkinson's disease patients.
Topics: Aged; Electron Spin Resonance Spectroscopy; Female; Ferric Compounds; Ferritins; Humans; Iron; Male; Manganese; Melanins; Microwaves; Parkinson Disease; Substantia Nigra; Temperature | 2000 |
Manganese increases L-DOPA auto-oxidation in the striatum of the freely moving rat: potential implications to L-DOPA long-term therapy of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Chlorides; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis Solutions; Dopamine; Homovanillic Acid; Infusion Pumps; Levodopa; Male; Manganese; Manganese Compounds; Microdialysis; Movement; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Wistar; Time Factors; Uric Acid | 2000 |
Welding-related parkinsonism: clinical features, treatment, and pathophysiology.
Topics: Adult; Age of Onset; Aged; Case-Control Studies; Dihydroxyphenylalanine; Female; Humans; Male; Manganese; Middle Aged; Neostriatum; Occupational Diseases; Occupational Exposure; Parkinson Disease; Risk Factors; Tomography, Emission-Computed; Welding | 2001 |
The distribution of copper, zinc- and manganese-superoxide dismutase, and glutathione peroxidase messenger ribonucleic acid in rat basal ganglia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Copper; Disease Models, Animal; Glutathione Peroxidase; Male; Manganese; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Zinc | 2002 |
The relationship between Parkinson syndrome and vascular siderosis: an electron microprobe study.
Topics: Aged; Aluminum; Barium; Calcium; Cerebral Arterial Diseases; Electron Probe Microanalysis; Female; Globus Pallidus; Humans; Iron; Lead; Magnesium; Male; Manganese; Middle Aged; Parkinson Disease; Phosphorus; Potassium; Siderosis; Sulfur; Zinc | 1977 |
Role of manganese in dystonia.
Topics: Animals; Brain; Brain Chemistry; Dogs; Dystonia Musculorum Deformans; Functional Laterality; Gait; Haplorhini; Humans; Levodopa; Manganese; Manganese Poisoning; Movement Disorders; Parkinson Disease; Rabbits; Rats; Synapses; Syndrome | 1976 |
A case control study of CSF copper, iron and manganese in Parkinson disease.
Topics: Aged; Case-Control Studies; Copper; Female; Humans; Iron; Male; Manganese; Middle Aged; Parkinson Disease | 1992 |
Manganese as possible ecoetiologic factor in Parkinson's disease.
Topics: Cohort Studies; Humans; Manganese; Occupational Exposure; Parkinson Disease; Parkinson Disease, Secondary | 1992 |
Does signal-attenuation on high-field T2-weighted MRI of the brain reflect regional cerebral iron deposition? Observations on the relationship between regional cerebral water proton T2 values and iron levels.
Topics: Body Water; Brain; Caudate Nucleus; Cerebral Cortex; Copper; Humans; Iron; Magnetic Resonance Imaging; Manganese; Parkinson Disease | 1989 |
Raised cerebrospinal-fluid copper concentration in Parkinson's disease.
Topics: Adult; Copper; Female; Humans; Iron; Male; Manganese; Middle Aged; Parkinson Disease; Phenanthrolines; Severity of Illness Index; Spectrophotometry, Atomic | 1987 |
Tyrosine hydroxylase and parkinsonism.
Topics: Animals; Brain; Carbon Monoxide; Catecholamines; Dopamine; Haplorhini; Humans; Manganese; Mixed Function Oxygenases; Parkinson Disease; Parkinson Disease, Secondary; Serotonin; Substantia Nigra; Tyrosine | 1971 |
Functional interactions between biogenic amines, 3',5'-cyclic AMP and manganese.
Topics: Adenine Nucleotides; Animals; Bile; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Epinephrine; Glucagon; Humans; Isoproterenol; Liver; Manganese; Manganese Poisoning; Parkinson Disease; Radioisotopes; Rats | 1968 |
Clinical manganism and exposure to manganese in the production and processing of ferromanganese alloy.
Topics: Air Pollution; Calcium; Central Nervous System Diseases; Diagnosis, Differential; Dust; Edetic Acid; Environmental Exposure; Humans; Iron; Male; Manganese; Maximum Allowable Concentration; Middle Aged; Occupational Diseases; Parkinson Disease; Ventilation | 1973 |
Parkinsoism anDopa.
Topics: Dihydroxyphenylalanine; Dopamine; Humans; Manganese; Manganese Poisoning; Parkinson Disease | 1969 |
Metabolic modification of some neurologic disorders.
Topics: Dihydroxyphenylalanine; Dopamine; Humans; Male; Manganese; Manganese Poisoning; Parkinson Disease; Poisoning; Pyridoxine | 1969 |
[On the distribution of trace elements (manganese, copper, zinc, and gold) in serum and cerebrospinal fluid in epilepsy and parkinsonism].
Topics: Copper; Epilepsy; Gold; Humans; Manganese; Neutrons; Parkinson Disease; Radiometry; Trace Elements; Zinc | 1967 |
Amyotrophic lateral sclerosis and parkinsonism-dementia complex of Guam. Neurological reevaluation.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Encephalitis, Arbovirus; Female; Humans; Intellectual Disability; Male; Manganese; Middle Aged; Pacific Islands; Parkinson Disease | 1966 |