manganese has been researched along with Huntington Disease in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 12 (48.00) | 24.3611 |
| 2020's | 9 (36.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowman, AB; Cox, EC; Debbiche, IF; Erikson, KM; Harrison, FE; Pfalzer, AC; Tienda, AA; Totten, MS; Wilcox, JM | 1 |
| Bowman, AB; Calipari, ES; Consoli, DC; Harrison, FE; Paffenroth, KC; Spitznagel, BD; Wilcox, JM | 1 |
| Bowman, AB; Claassen, DO; Erikson, K; Kang, H; Pfalzer, AC; Silverman, J; Totten, M; Yan, Y | 1 |
| Clares, MP; García-España, E; Merino, M; Mullor, JL; Sánchez-Sánchez, AV; Sequedo, MD; Vázquez-Manrique, RP | 1 |
| Boudi, A; Chhetri, G; DiFiglia, M; Ghosh, A; Islam, MA; Ke, Y; Li, X; Li, Y; Sapp, E; Usman, M; Wang, J; Wang, P; Wang, X | 1 |
| Huang, EJ; Marsan, E | 1 |
| Cooper, GJS; Patassini, S; Scholefield, M; Xu, J | 1 |
| Aschner, M; Bodnya, C; Bowman, AB; Ilieva, I; Joshi, P; Neely, MD | 1 |
| Aschner, M; Bowman, AB; Bryan, MR; Di Pardo, A; Foshage, AM; Joshi, P; Maglione, V; Nitin, R; Nordham, KD; O'Brien, MT; Rose, DIR; Uhouse, MA; Zhang, Z | 1 |
| Aschner, M; Bichell, TJV; Bowman, AB; Codreanu, SG; Erikson, KM; Halbesma, T; Harrison, FE; McLean, JA; Parmalee, NL; Pfalzer, AC; Sherrod, SD; Totten, M; Umashanker, P; Wilcox, JM; Yang, KL | 1 |
| Aschner, M; Bowman, AB; Bryan, MR; Hardeman, KN; Morcillo, P; Warren, EB | 1 |
| Bowman, AB; Bryan, MR | 1 |
| Bowman, AB; Pfalzer, AC; Porter, NA; Wages, PA | 1 |
| Aboud, AA; Aschner, M; Bowman, AB; Bryan, MR; Ess, KC; Feist, JE; Kumar, KK; Neely, MD; Tidball, AM; Uhouse, MA | 1 |
| Aschner, M; Bornhorst, J; Bowman, AB; Goodwin, CR; Kumar, KK; McLean, JA; Schwerdtle, T; Uhouse, MA | 1 |
| Aschner, M; Bowman, AB; Caito, SW; Horning, KJ; Tipps, KG | 1 |
| Aschner, M; Bichell, TJV; Bowman, AB; Bradley, EM; Bryan, M; Colbran, RJ; Di Pardo, A; Dudek, K; Fisher, N; Halbesma, T; Holt, HK; Horning, K; Kwakye, GF; Maglione, V; Neely, MD; Osmand, A; Stubbs, AD; Tidball, AM; Tipps, KG; Uhouse, MA; Umashanker, P; Wegrzynowicz, M | 1 |
| Anderson, JG; Aschner, M; Bowman, AB; Erikson, KM; Kwakye, GF; Li, D; Vadodaria, BK; Wegrzynowicz, M; Williams, BB | 1 |
| Aschner, M; Bowman, AB; Erikson, KM; Kwakye, GF; Li, D; Wegrzynowicz, M; Williams, BB | 1 |
| Bowman, AB; Kwakye, GF; Li, D | 1 |
| Aschner, M; Bowman, AB; Madison, JL; Wegrzynowicz, M | 1 |
| Norenberg, MD; Rao, KV | 1 |
| Borisova, TV | 1 |
| Cotzias, GC; Gellene, R; Papavasiliou, PS | 1 |
| Bird, ED; Heathfield, KW; Pilling, JB | 1 |
3 review(s) available for manganese and Huntington Disease
| Article | Year |
|---|---|
Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Autophagy; Brain; Disease Models, Animal; Humans; Huntingtin Protein; Huntington Disease; Insulin; Manganese; Mitochondria; Neostriatum; Neural Stem Cells; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Signal Transduction; Somatomedins | 2017 |
Manganese Is Essential for Neuronal Health.
Topics: Arginase; Bile; Blood-Brain Barrier; Brain; Enzyme Activation; Glutamate-Ammonia Ligase; Health Status; Homeostasis; Humans; Huntington Disease; Intestinal Absorption; Manganese; Nervous System Diseases; Neurons; Parkinson Disease | 2015 |
The mitochondrial permeability transition in neurologic disease.
Topics: Alzheimer Disease; Calcium; Energy Metabolism; Humans; Huntington Disease; Hyperglycemia; Manganese; Mitochondrial Membranes; Mitochondrial Swelling; Motor Neuron Disease; Nervous System Diseases; Neurodegenerative Diseases; Neurotoxins; Parkinsonian Disorders; Permeability | 2007 |
1 trial(s) available for manganese and Huntington Disease
| Article | Year |
|---|---|
Modification of Parkinsonism--chronic treatment with L-dopa.
Topics: Adult; Aged; Agranulocytosis; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Urea Nitrogen; Blood-Brain Barrier; Chronic Disease; Dihydroxyphenylalanine; Dopamine; Feeding and Eating Disorders; Female; Humans; Huntington Disease; Male; Manganese; Mental Processes; Methyldopa; Middle Aged; Movement Disorders; Nausea; Neurologic Manifestations; Parkinson Disease; Phenylacetates; Placebos; Thyroid Function Tests; Tyrosine; Vomiting | 1969 |
21 other study(ies) available for manganese and Huntington Disease
| Article | Year |
|---|---|
YAC128 mouse model of Huntington disease is protected against subtle chronic manganese (Mn)-induced behavioral and neuropathological changes.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hand Strength; Huntington Disease; Male; Manganese; Maze Learning; Mice; Mice, Transgenic; Neuroprotective Agents; Open Field Test; Rotarod Performance Test | 2021 |
Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype.
Topics: Age Factors; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Genotype; Huntington Disease; Hyperkinesis; Manganese; Mice; Motor Activity; Nucleus Accumbens; Serotonin; Sex Factors; Tyrosine 3-Monooxygenase | 2022 |
Alterations in metal homeostasis occur prior to canonical markers in Huntington disease.
Topics: Biomarkers; Copper; Homeostasis; Humans; Huntington Disease; Iron; Manganese; Metals; Zinc | 2022 |
Mn(II) Quinoline Complex (4QMn) Restores Proteostasis and Reduces Toxicity in Experimental Models of Huntington's Disease.
Topics: Animals; Disease Models, Animal; Humans; Huntingtin Protein; Huntington Disease; Manganese; Models, Theoretical; Proteasome Endopeptidase Complex; Proteostasis; Quinolines | 2022 |
Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease.
Topics: Amino Acid Transport Systems, Neutral; Animals; Corpus Striatum; Endosomes; Huntington Disease; Manganese; Mice; Neurons; Proteome; rab GTP-Binding Proteins | 2022 |
Endosomal recycling defects link Huntington's disease with McLeod syndrome.
Topics: Amino Acid Transport Systems, Neutral; Cell Membrane; Endosomes; Humans; Huntington Disease; Manganese; Neuroacanthocytosis; rab GTP-Binding Proteins | 2022 |
Widespread selenium deficiency in the brain of cases with Huntington's disease presents a new potential therapeutic target.
Topics: Brain; Calcium; Copper; Humans; Huntington Disease; Iron; Manganese; Neurodegenerative Diseases; Potassium; Selenium; Sodium; Zinc | 2023 |
Huntington's disease associated resistance to Mn neurotoxicity is neurodevelopmental stage and neuronal lineage dependent.
Topics: Brain; Case-Control Studies; Cell Differentiation; Cell Lineage; Corpus Striatum; Dose-Response Relationship, Drug; Female; Humans; Huntington Disease; Induced Pluripotent Stem Cells; Male; Manganese; Mesencephalon; Neurons | 2019 |
Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell lines.
Topics: Animals; Autophagosomes; Autophagy; Cell Line; Disease Models, Animal; HEK293 Cells; Humans; Huntingtin Protein; Huntington Disease; Induced Pluripotent Stem Cells; Manganese; Mice; Microscopy, Electron; Mutation; Neurons | 2019 |
Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice.
Topics: Animals; Disease Models, Animal; Genotype; Huntington Disease; Manganese; Mice | 2020 |
Manganese-induced Mitochondrial Dysfunction Is Not Detectable at Exposures Below the Acute Cytotoxic Threshold in Neuronal Cell Types.
Topics: Cell Line; Corpus Striatum; Humans; Huntington Disease; Manganese; Mitochondria; Neurons | 2020 |
Striatal Cholesterol Precursors Are Altered with Age in Female Huntington's Disease Model Mice.
Topics: Aging; Animals; Cholesterol; Corpus Striatum; Disease Models, Animal; Female; Huntington Disease; Male; Manganese; Mice; Mice, Transgenic | 2019 |
A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.
Topics: Amino Acid Motifs; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Line; Corpus Striatum; Disease Models, Animal; DNA Damage; Female; Humans; Huntington Disease; Male; Manganese; Mice; Neural Stem Cells; Phosphorylation; Signal Transduction; Tumor Suppressor Protein p53 | 2015 |
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status.
Topics: Animals; Cell Line; Huntington Disease; Manganese; Metabolomics; Mice; Models, Biological; Neurons; Principal Component Analysis | 2015 |
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.
Topics: Animals; Arginase; Corpus Striatum; Disease Models, Animal; Huntington Disease; Male; Manganese; Mice; Neurons; Urea | 2017 |
Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure.
Topics: Animals; Cattle; Cell Line; Cell Survival; Drug Evaluation, Preclinical; Humans; Huntingtin Protein; Huntington Disease; Manganese; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins | 2010 |
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.
Topics: Animals; Biological Transport; Cation Transport Proteins; Corpus Striatum; Disease Models, Animal; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Iron; Manganese; Mice; Nerve Tissue Proteins; Nuclear Proteins | 2010 |
Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation.
Topics: Animals; Cell Line; Corpus Striatum; Fura-2; High-Throughput Screening Assays; Huntington Disease; Manganese; Mice; Mice, Mutant Strains; Mutation | 2011 |
Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism.
Topics: Animals; Dendrites; Dopamine; Environmental Exposure; Genotype; Huntington Disease; Male; Manganese; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multivariate Analysis; Neostriatum; Neurons | 2012 |
[Microelement metabolism in patients with hereditary extrapyramidal diseases].
Topics: Adolescent; Adult; Brain Diseases; Child; Dystonia Musculorum Deformans; Humans; Huntington Disease; Iron; Manganese; Middle Aged; Pantothenate Kinase-Associated Neurodegeneration; Trace Elements; Zinc | 1978 |
Penicillamine in Huntington's chorea.
Topics: Humans; Huntington Disease; Manganese; Penicillamine | 1974 |