manganese has been researched along with Aging in 139 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (43.88) | 18.7374 |
| 1990's | 26 (18.71) | 18.2507 |
| 2000's | 22 (15.83) | 29.6817 |
| 2010's | 23 (16.55) | 24.3611 |
| 2020's | 7 (5.04) | 2.80 |
| Authors | Studies |
|---|---|
| Balygina, I; Chen, X; Conze, IH; Daly, MJ; Gaidamakova, EK; Gostinčar, C; Grichenko, O; Hoffman, BM; Horne, WH; Jackson-Thompson, B; Klimenkova, P; Makarova, KS; Matrosova, VY; Sharma, A; Shuryak, I; Srinivasan, C; Tkavc, R; Volpe, RP | 1 |
| Boyken, J; Frenzel, T; Green, C; Jost, G; Pietsch, H; Schwenke, C | 1 |
| Edler, MK; Guilarte, TR; McGlothan, JL; Rodichkin, AN | 1 |
| Amarasiriwardena, C; Baccarelli, AA; Coull, BA; Heiss, J; Hou, L; Jin, T; Just, A; Kosheleva, A; Li, W; Peralta, AA; Qiu, X; Schwartz, JD; Sparrow, D; Wang, C; Wei, Y; Wright, RO; Xu, Z; Yazdi, MD; Zheng, Y | 1 |
| Cui, J; Feng, Y; Guo, Y; Hou, Q; Jia, M; Jiang, Q; Li, G; Li, J; Li, T; Lv, Z; Wang, L; Wang, Y; Zhang, B; Zhang, M | 1 |
| Bi, J; Chen, K; Li, Y; Liu, Q; Liu, Y; Song, L; Wang, L; Wang, Y; Wu, M; Xia, W; Xiong, C; Xu, S; Zhou, A | 1 |
| Aschner, M; Baesler, J; Bornhorst, J; Haase, H; Michaelis, V; Schwerdtle, T; Stiboller, M; Sturzenbaum, SR | 1 |
| Bowman, AB; Pfalzer, AC | 1 |
| Abisambra, JF; Cloyd, RA; Di Domenico, F; Fontaine, SN; Ingram, A; Lanzillotta, C; Lyons, D; Mechas, E; Meier, SE; Miller, E; Nation, GK; Powell, DK; Schmitt, F; Vandsburger, M; Weiss, B | 1 |
| Bowman, AB; Pfalzer, AC; Porter, NA; Wages, PA | 1 |
| Abdulla, ZI; Crawford, CA; Kaplan, GJ; Lee, RJ; McDougall, SA; Mohd-Yusof, A | 1 |
| Cappai, R; Ciccotosto, GD; Needham, BE | 1 |
| Berkowitz, BA; Grady, EM; Roberts, R | 1 |
| Andersen, JK; Angeli, S; Barhydt, T; Jacobs, R; Killilea, DW; Lithgow, GJ | 1 |
| Almeida, A; Magalhães, T; Mendes, R; Pinto, NR; Ramos, P; Santos, A | 1 |
| Boaru, SG; Matusch, A; Merle, U; Stremmel, W; Uerlings, R; Weiskirchen, R; Weiskirchen, S; Zimmermann, A | 1 |
| Baralla, A; Bocca, B; Carru, C; Deiana, L; Deiana, M; Forte, G; Madeddu, R; Mura, I; Muresu, E; Occhineri, P; Pasella, S; Sotgia, S; Zinellu, A | 1 |
| Aschner, M; Bornhorst, J; Bowman, AB; Chen, P; DeWitt, MR; Mukhopadhyay, S; Soares, FA | 1 |
| Choi, YS; Jain, RB | 1 |
| Chien, CT; Hsu, CH; Lin, CL; Sheu, SJ; Wang, SE; Wu, CH | 1 |
| Bush, AI; Faux, NG; Hare, DJ; Martins, RN; Roberts, BR; Volitakis, I | 1 |
| Aschner, M; Parmalee, NL | 1 |
| Chang, H; Huang, G; Li, Z; Liu, W; Liu, Y; Lui, G; Wang, X; Zhang, M | 1 |
| Dietrich, KN; Haynes, EN; Vollet, K | 1 |
| Iida, M; Kato, M; Kumasaka, MY; Li, X; Ohgami, N; Oshino, R; Yajima, I | 1 |
| Du, K; Liu, M; Pan, Y; Wei, M; Zhong, X | 1 |
| Legare, ME; Moreno, JA; Streifel, KM; Sullivan, KA; Tjalkens, RB | 1 |
| Chimedregzen, U; Ishiguro, K; Kagawa, Y; Kawabata, T; Komatsu, F; Otgon, J; Purvee, B | 1 |
| Berkowitz, BA; Bissig, D; Roberts, R | 1 |
| Aschner, M; Au, C; Avila, DS; Benedetto, A; Milatovic, D | 1 |
| Covy, JP; Giasson, BI | 1 |
| Amarasiriwardena, C; Baccarelli, A; Hu, H; Litonjua, A; Mordukhovich, I; Schwartz, J; Sparrow, D; Vokonas, P; Wright, RO | 1 |
| Beyreuther, K; Bush, AI; Cappai, R; Cherny, RA; Li, QX; Masters, CL; Maynard, CJ; Volitakis, I; White, AR | 1 |
| Hrbasová, M; Kolár, F; Novotny, J; Svoboda, P | 1 |
| Kaiser, J | 1 |
| Bain, MM; Mabe, I; Nys, Y; Rapp, C | 1 |
| Balietti, M; Bertoni-Freddari, C; Fattoretti, P; Mocchegiani, E; Scancar, J; Zambenedetti, P; Zatta, P | 1 |
| Dorman, DC; James, RA; Marshall, MW; McManus, BE; Struve, MF | 1 |
| Cousins, MM; Seidler, FJ; Slotkin, TA; Tate, CA | 1 |
| Jackowski, G; Zelisko, A | 1 |
| Blind, JA; Duan, X; Joyner, AL; Moreno, C; Turnbull, DH; Wadghiri, YZ; Yu, X | 1 |
| Cross, DH; Harper, ER; Mazzaro, L; Puschner, B; Reidarson, TH; Schmitt, T; St Leger, JA; Tucker, M; Westberg, JA | 1 |
| Anzai, Y; Cross, DJ; Flexman, JA; Maravilla, KR; Minoshima, S | 1 |
| Aydemir, B; Cakatay, U; Kayali, R; Kiziler, AR | 1 |
| Cross, D; Minoshima, S | 1 |
| Bae, YJ; Kim, MH | 1 |
| Brotto, M; Campbell, R; Ma, J; Oppong, Y; Thornton, A; Weisleder, N; Zhao, X | 1 |
| Chandra, SV; Dubey, MP; Shukla, GS | 1 |
| Lai, JC; Leung, TK; Lim, L | 5 |
| Benardo, LS; Connors, BW; Prince, DA | 1 |
| DiGuiseppi, J; Fridovich, I | 1 |
| Saito, J; Sawai, Y; Tsukada, K | 1 |
| Kawai, M; Nomura, Y | 1 |
| Cooper, WC | 1 |
| Caple, IW; Paynter, DI | 1 |
| Kauf, E; Niese, S; Plenert, W; Wiesner, W | 1 |
| Alauddin, M; Ehmann, WD; Hossain, TI; Markesbery, WR | 1 |
| Hurley, LS; Keen, CL; Lönnerdal, B; Zidenberg-Cherr, S | 1 |
| Inaba, J; Nishimura, Y | 1 |
| Favier, A; Ruffieux, D | 1 |
| Hudec, R; Mehnert, E | 1 |
| George, BL; Jarmakani, JM | 1 |
| Davison, AN; Guest, JF; Lai, JC; Leung, TK; Lim, L | 1 |
| Carter, SD; Hein, JF; Laskey, JW; Linko, RS; Rehnberg, GL | 1 |
| Hacker, CS; Hulse, M; Mahoney, JS; Pier, SM; Schroder, GD | 1 |
| de Rosa, G; Hurley, LS; Keen, CL; Leach, RM | 1 |
| Carter, SD; Hein, JF; Laskey, JW; Rehnberg, GL | 1 |
| Bercegeay, MS; Cahill, DF; Gerding, JE; Gray, LE; Haggerty, RC | 1 |
| Allegri, G; Costa, C; Doretti, L; Parvoli, G; Sturaro, A | 1 |
| Kirchgessner, M; Kreuzer, M; Roth, FX | 1 |
| Bayliss, DA; Berger, AJ; Kanter, RK; Millhorn, DE; Szymeczek-Seay, CL; Viana, F | 1 |
| Ahotupa, M; Huhtaniemi, I; Peltola, V | 1 |
| Borch-Iohnsen, B; Nilssen, KJ; Norheim, G | 1 |
| Itokawa, Y; Kimura, M; Takeda, T; Yokoi, K | 1 |
| Ayala, A; Revilla, E; Santa María, C | 1 |
| Ikeda, K; Suzuki, H; Takasaka, T | 1 |
| Haga, S; Kizaki, T; Oh-ishi, S; Ohno, H; Ookawara, T; Toshinai, K | 1 |
| Klein, J; Kruse-Jarres, JD; Rükgauer, M | 1 |
| Asano, M; Fujinaga, T; Okumura, M; Tagami, M; Tsukiyama, K | 1 |
| McCook, EC; Seidler, FJ; Slotkin, TA; Zhang, J | 1 |
| Barré, P; Berthouloux, B; Bonté, F; Chaudagne, C; Dumas, M; Le Varlet, B; Meybeck, A; Saunois, A; Sauvage, C | 1 |
| Mohanna, C; Nys, Y | 1 |
| Ishiwatari, S; Okada, S; Takeda, A | 1 |
| Chow, FA; McCook, EC; Seidler, FJ; Slotkin, TA | 1 |
| Delogu, MR; Desole, MS; Esposito, G; Miele, M; Migheli, R; Rocchitta, G; Serra, PA | 1 |
| Delogu, MR; Desole, MS; Esposito, G; Fresu, L; Miele, M; Migheli, R; Rocchitta, G; Serra, PA | 1 |
| Bolann, BJ; Myking, A; Rahil-Khazen, R; Ulvik, RJ | 1 |
| Cano, J; Cruz Sánchez-Hidalgo, M; Herrera, AJ; Machado, A; Tomás-Camardiel, M; Venero, JL | 1 |
| Corradetti, E; Nagy, IZ; Szeszák, F | 1 |
| Earp, HS; Spruill, WA; Steiner, AL | 1 |
| Baird, CE; Hardman, YJ; Wells, JN; Wu, JG | 1 |
| Mookerjea, S; Schimmer, BP | 1 |
| Knuuttila, M; Lappalainen, R | 1 |
| Burch, RE; Hahn, HK | 1 |
| Fox, MR; Fry, BE; Jacobs, RM; Jones, AO | 1 |
| del Castilho, P; Herber, RF; Wibowo, AA; Zielhuis, RL | 1 |
| Matonoha, P; Zechmeister, A | 1 |
| Koirtyohann, SR; Masironi, R; Pierce, JO; Schamschula, RG | 1 |
| Gupta, SK; Rothstein, M | 1 |
| Baquer, NZ; Greenbaum, AL; Hothersall, JS; McLean, P | 1 |
| Cox, D; Giufrida, AM; Mathias, AP | 1 |
| Iizuka, S; Ishikawa, M; Kawamura, N; Mino, M; Miyake, M; Suzuki, K; Taniguchi, N | 1 |
| Fukudome, A; Hagino, T; Kawano, K; Kimura, M; Kito, M; Nakajima, K; Otaki, N; Sakurai, H; Takeshima, S; Tawa, R | 1 |
| Agata, N; Shigenobu, K; Tanaka, H | 1 |
| Garcia, B; Sinha, AA; Wilson, MJ; Woodson, M | 1 |
| Borrello, S; De Leo, ME; Galeotti, T | 1 |
| Halliday, HL; McMaster, D; Tubman, TR; Wilson, DC | 1 |
| Chan, AW; Lai, JC; Lim, L; Minski, MJ | 1 |
| Churina, SK; Didenko, AV; Ianushkene, TS; Kuznetsov, SR; Puz'ko, IuO; Samoĭlov, MO; Semenov, DG | 1 |
| Cui, L; Dong, C; Li, S; Wang, S | 1 |
| Arechaga, G; de Gandarias, JM; Garcia, S; Lardelli, P; Ramírez, M; Sanchez, B | 1 |
| Brannon, PM; Collins, VP; Korc, M | 1 |
| Cai, XM; Zhu, BR | 1 |
| Valois, AA; Webster, WS | 1 |
| Gruden, N; Matausić, S | 1 |
| Alikhan, MA; Bercovitz, K | 1 |
| Blanusa, M; Kello, D; Kostial, K; Maljković, T; Rabar, I; Stara, JF | 1 |
| Villa-Moruzzi, E | 1 |
| Glowacki, J; Saltman, P; Strause, L | 1 |
| Solomons, NW | 1 |
| Bell, JG; Keen, CL; Lönnerdal, B | 1 |
| Hegstrand, LR; Kalinke, TH | 1 |
| Baly, DL; Hurley, LS; Keen, CL | 1 |
| Yase, Y | 1 |
| Zapadniuk, VI | 1 |
| Margulies, MM | 1 |
| Van der Lande, VM | 1 |
| Dmitriev, AE; Gagulashvili, AD; Iumashev, GS | 1 |
| Prescott, JM; Wilkes, SH | 1 |
| Dain, JA; Yip, GB | 1 |
| Aposkitis, C | 1 |
| Dain, JA; Dicesare, JL | 1 |
| Fujiwara, M; Hattori, K; Mori, J; Sakurai, I; Shibata, S | 1 |
| Jeter, J; Swanson, AA; Tucker, P | 1 |
| Ito, T | 1 |
9 review(s) available for manganese and Aging
| Article | Year |
|---|---|
Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease.
Topics: Aging; Central Nervous System Diseases; Humans; Manganese; Manganese Poisoning; Neurotoxicity Syndromes; Risk Factors | 2017 |
Manganese and aging.
Topics: Aging; Animals; Humans; Manganese; Manganese Poisoning | 2016 |
Manganese Exposure and Cognition Across the Lifespan: Contemporary Review and Argument for Biphasic Dose-Response Health Effects.
Topics: Aging; Cognition; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Pollutants; Epidemiologic Studies; Humans; Manganese; Manganese Poisoning; Neuropsychological Tests; Occupational Exposure; Pediatrics | 2016 |
Association of Serum Manganese Levels with Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.
Topics: Aging; Alzheimer Disease; Animals; Cognitive Dysfunction; Deficiency Diseases; Diet; Elder Nutritional Physiological Phenomena; Environmental Pollutants; Evidence-Based Medicine; Humans; Manganese; Prodromal Symptoms; Risk Factors | 2017 |
α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease.
Topics: Aging; alpha-Synuclein; Amino Acid Sequence; Animals; Cell Membrane; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Manganese; Molecular Sequence Data; Mutation, Missense; Parkinson Disease; Protein Serine-Threonine Kinases | 2011 |
In vivo imaging of axonal transport using MRI: aging and Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Animals; Axons; Brain; Contrast Media; Image Enhancement; Magnetic Resonance Imaging; Manganese; Mice; Neural Pathways; Rats | 2008 |
The toxicology of molecular oxygen.
Topics: Aging; Animals; Copper; Escherichia coli; Humans; Hydrogen Peroxide; Inflammation; Interferons; Iron; Manganese; Neoplasms, Experimental; Oxidation-Reduction; Oxygen; Superoxide Dismutase; Superoxides; Zinc | 1984 |
The health implications of increased manganese in the environment resulting from the combustion of fuel additives: a review of the literature.
Topics: Aging; Air Pollutants; Air Pollutants, Occupational; Animals; Basal Ganglia Diseases; Carcinogens; Disease Susceptibility; Food Analysis; Gasoline; Hematopoiesis; Humans; Intestinal Absorption; Iron Deficiencies; Lung; Lung Diseases; Manganese; Manganese Poisoning; Maximum Allowable Concentration; Mutagens; Occupational Diseases; Organometallic Compounds; Petroleum; Reproduction; Soil Pollutants; Tissue Distribution; Water Pollutants, Chemical | 1984 |
Trace elements in human nutrition.
Topics: Aging; Chelating Agents; Child, Preschool; Copper; Hepatolenticular Degeneration; Humans; Infant; Manganese; Menkes Kinky Hair Syndrome; Nutritional Physiological Phenomena; Proteins; Socioeconomic Factors; Tissue Distribution; Trace Elements; Zinc | 1979 |
130 other study(ies) available for manganese and Aging
| Article | Year |
|---|---|
Small-Molecule Mn Antioxidants in Caenorhabditis elegans and Deinococcus radiodurans Supplant MnSOD Enzymes during Aging and Irradiation.
Topics: Aging; Animals; Antioxidants; Caenorhabditis elegans; Deinococcus; Manganese; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2022 |
The Effect of Gadolinium-Based Contrast Agents on Longitudinal Changes of Magnetic Resonance Imaging Signal Intensities and Relaxation Times in the Aging Rat Brain.
Topics: Aging; Animals; Body Weight; Brain; Cerebellar Nuclei; Contrast Media; Gadolinium; Gadolinium DTPA; Iron; Magnetic Resonance Imaging; Manganese; Organometallic Compounds; Rats; Rats, Wistar; Retrospective Studies | 2022 |
Pathophysiological studies of aging Slc39a14 knockout mice to assess the progression of manganese-induced dystonia-parkinsonism.
Topics: Aging; Animals; Cation Transport Proteins; Dystonia; Humans; Manganese; Mice; Mice, Knockout; Parkinsonian Disorders; Substantia Nigra | 2022 |
Epigenome-wide DNA methylation in leukocytes and toenail metals: The normative aging study.
Topics: Aged; Aging; Arsenic; Bayes Theorem; Cadmium; Cardiovascular Diseases; DNA Methylation; Epigenome; Humans; Leukocytes; Male; Manganese; Mercury; Metals; Nails | 2023 |
The ionome and proteome landscape of aging in laying hens and relation to egg white quality.
Topics: Aging; Amino Acids; Animals; Chickens; Egg White; Female; Manganese; Proteome; Selenium | 2023 |
Association between maternal urinary manganese concentrations and newborn telomere length: Results from a birth cohort study.
Topics: Adult; Aging; China; Cohort Studies; Environmental Pollutants; Female; Fetal Blood; Humans; Infant; Infant, Newborn; Male; Manganese; Maternal Exposure; Pregnancy; Pregnancy Trimesters; Real-Time Polymerase Chain Reaction; Telomere; Telomere Shortening | 2021 |
Nutritive Manganese and Zinc Overdosing in Aging C. elegans Result in a Metallothionein-Mediated Alteration in Metal Homeostasis.
Topics: Aging; Animals; Animals, Genetically Modified; Biological Availability; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dopaminergic Neurons; Drug Overdose; Homeostasis; Manganese; Metallothionein; Mutation; Toxicity Tests, Chronic; Ubiquitin-Protein Ligases; Zinc | 2021 |
Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach.
Topics: Aging; Alzheimer Disease; Animals; Disease Models, Animal; Early Diagnosis; Humans; Magnetic Resonance Imaging; Manganese; Mice, Transgenic; Neurodegenerative Diseases; Neuroimaging; Neurons; Sensitivity and Specificity; Tauopathies | 2017 |
Striatal Cholesterol Precursors Are Altered with Age in Female Huntington's Disease Model Mice.
Topics: Aging; Animals; Cholesterol; Corpus Striatum; Disease Models, Animal; Female; Huntington Disease; Male; Manganese; Mice; Mice, Transgenic | 2019 |
Postnatal manganese exposure does not alter dopamine autoreceptor sensitivity in adult and adolescent male rats.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Autoreceptors; Behavior, Animal; Corpus Striatum; Dopamine; Haloperidol; Male; Manganese; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine | 2013 |
Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Copper; Gene Deletion; Homeostasis; Iron; Manganese; Metals, Heavy; Mice; Mice, Inbred C57BL; Mice, Knockout; Zinc | 2014 |
Confirming a prediction of the calcium hypothesis of photoreceptor aging in mice.
Topics: Aging; Animals; Calcium Channels, L-Type; Color Vision; Diltiazem; Magnetic Resonance Imaging; Male; Manganese; Mice, Inbred C57BL; Photoreceptor Cells, Vertebrate; Rats; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells | 2014 |
Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Homeostasis; Iron; Manganese; Parkinson Disease; Protein Aggregates; Protein Aggregation, Pathological; Unfolded Protein Response | 2014 |
Anatomical region differences and age-related changes in copper, zinc, and manganese levels in the human brain.
Topics: Aged; Aged, 80 and over; Aging; Brain Chemistry; Copper; Female; Humans; Male; Manganese; Middle Aged; Putamen; Zinc | 2014 |
Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson's disease by laser ablation inductively coupled plasma mass spectrometry.
Topics: Actins; Adenosine Triphosphatases; Aging; Animals; Blotting, Western; Brain; Cation Transport Proteins; Copper; Copper-Transporting ATPases; Disease Models, Animal; Disease Progression; Hepatolenticular Degeneration; Iron; Laser Therapy; Manganese; Mass Spectrometry; Mice, 129 Strain; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha; Zinc | 2014 |
Metals in plasma of nonagenarians and centenarians living in a key area of longevity.
Topics: Aged, 80 and over; Aging; Calcium; Case-Control Studies; Cobalt; Copper; Female; Humans; Iron; Italy; Longevity; Magnesium; Male; Manganese; Metals; Middle Aged; Selenium | 2014 |
Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease.
Topics: Aging; Aldehyde Oxidoreductases; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopaminergic Neurons; Forkhead Transcription Factors; Gene Deletion; Green Fluorescent Proteins; Longevity; Manganese; Models, Biological; Models, Genetic; Movement; Parkinson Disease; Phenotype; Signal Transduction; Survival Analysis | 2015 |
Normal reference ranges for and variability in the levels of blood manganese and selenium by gender, age, and race/ethnicity for general U.S. population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Confidence Intervals; Female; Humans; Income; Male; Manganese; Middle Aged; Multivariate Analysis; Nutrition Surveys; Racial Groups; Reference Values; Regression Analysis; Selenium; Smoking; United States; Young Adult | 2015 |
Oral treatment with herbal formula B401 alleviates penile toxicity in aging mice with manganism.
Topics: Aging; Animals; Antioxidants; Apoptosis; Blotting, Western; Drugs, Chinese Herbal; Hazardous Substances; Heavy Metal Poisoning; Immunohistochemistry; Inflammation Mediators; Male; Manganese; Mice; Mice, Inbred ICR; Oxidative Stress; Penis; Plant Preparations; Poisoning; Vascular Endothelial Growth Factor A | 2015 |
Lead and manganese levels in serum and erythrocytes in Alzheimer's disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing.
Topics: Aged; Aging; Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Erythrocytes; Female; Humans; Image Processing, Computer-Assisted; Lead; Male; Manganese | 2016 |
Associations of Serum Manganese Levels with Prediabetes and Diabetes among ≥60-Year-Old Chinese Adults: A Population-Based Cross-Sectional Analysis.
Topics: Aged; Aged, 80 and over; Aging; Blood Glucose; China; Community Health Centers; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Geriatric Assessment; Humans; Hypoglycemic Agents; Male; Manganese; Middle Aged; Models, Biological; Prediabetic State; Prevalence; Risk Factors; Self Report; Sex Factors | 2016 |
Manganese-mediated acceleration of age-related hearing loss in mice.
Topics: Aging; Animals; Disease Models, Animal; Hearing Loss; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Manganese; Mice; Mice, Transgenic; Nerve Degeneration; Phosphorylation; Proline; Proto-Oncogene Proteins c-ret; Spiral Ganglion; Up-Regulation | 2016 |
Developmental exposure to manganese increases adult susceptibility to inflammatory activation of glia and neuronal protein nitration.
Topics: Aging; Animals; Female; Immunohistochemistry; Manganese; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroglia; Neurons; Nitrates; Pregnancy | 2009 |
The association of very high hair manganese accumulation and high oxidative stress in Mongolian people.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Child; Female; Food Analysis; Hair; Humans; Japan; Male; Manganese; Middle Aged; Mongolia; Oxidative Stress; Soil; Water; Young Adult | 2009 |
Light-dependant intraretinal ion regulation by melanopsin in young awake and free moving mice evaluated with manganese-enhanced MRI.
Topics: Aging; Animals; Darkness; Ions; Light; Magnetic Resonance Imaging; Manganese; Mice; Mice, Inbred C57BL; Movement; Retina; Rod Opsins; Wakefulness | 2010 |
Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Extracellular Space; Female; Humans; Life Expectancy; Male; Manganese; Nerve Degeneration; Neurons; Oxidative Stress; Oxidoreductases; Parkinson Disease; Protein Transport | 2010 |
Associations of toenail arsenic, cadmium, mercury, manganese, and lead with blood pressure in the normative aging study.
Topics: Aged; Aging; Arsenic; Blood Pressure; Boston; Cadmium; Cohort Studies; Environmental Exposure; Environmental Health; Environmental Pollutants; Humans; Hypertension; Lead; Male; Manganese; Mercury; Metals, Heavy; Nails | 2012 |
Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cobalt; Copper; Female; Homeostasis; Humans; Iron; Male; Manganese; Mice; Mice, Inbred Strains; Mice, Transgenic; Zinc | 2002 |
Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Colforsin; Fluorides; Gene Expression; GTP-Binding Proteins; Hypertrophy, Left Ventricular; Isoproterenol; Manganese; Myocardium; Pressure; Protein Isoforms; Rats; Rats, Wistar; Signal Transduction | 2003 |
Manganese: a high-octane dispute.
Topics: Aging; Air Pollutants; Animals; Blood-Brain Barrier; Brain; Canada; Gasoline; Humans; Inhalation Exposure; Iron; Iron Deficiencies; Lung; Manganese; Manganese Poisoning; Maximum Allowable Concentration; Organometallic Compounds; Parkinson Disease, Secondary; Risk Factors; Threshold Limit Values; Toxicity Tests; United States; United States Environmental Protection Agency; Vehicle Emissions | 2003 |
Supplementation of a corn-soybean meal diet with manganese, copper, and zinc from organic or inorganic sources improves eggshell quality in aged laying hens.
Topics: Aging; Animals; Biomechanical Phenomena; Chickens; Copper; Diet; Dietary Supplements; Egg Shell; Egg Yolk; Eggs; Female; Glycine max; Manganese; Zea mays; Zinc | 2003 |
The effect of chronic aluminum(III) administration on the nervous system of aged rats: clues to understand its suggested role in Alzheimer's disease.
Topics: Aggression; Aging; Aluminum; Animals; Brain; Cerebellum; Copper; Hippocampus; Male; Manganese; Medulla Oblongata; Mesencephalon; Pons; Prosencephalon; Pyramidal Cells; Rats; Rats, Wistar; Zinc | 2003 |
Old age and gender influence the pharmacokinetics of inhaled manganese sulfate and manganese phosphate in rats.
Topics: Administration, Inhalation; Aging; Animals; Body Weight; Female; Male; Manganese; Manganese Compounds; Neostriatum; Organ Size; Organometallic Compounds; Radioisotopes; Rats; Sex Characteristics; Sulfates; Tissue Distribution | 2004 |
Serotonergic cell signaling in an animal model of aging and depression: olfactory bulbectomy elicits different adaptations in brain regions of young adult vs aging rats.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Aging; Animals; Colforsin; Depression; GTP-Binding Proteins; Male; Manganese; Neurotransmitter Agents; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Signal Transduction; Stimulation, Chemical | 2005 |
Senescence-dependent degradation of Lhcb3 is mediated by a thylakoid membrane-bound protease.
Topics: Aging; Chlorophyll; Hordeum; Hydrogen-Ion Concentration; Light; Light-Harvesting Protein Complexes; Magnesium; Manganese; Membrane Proteins; Plant Leaves; Protease Inhibitors; Thermolysin; Thylakoids; Time Factors; Zinc | 2004 |
Manganese-enhanced magnetic resonance imaging (MEMRI) of mouse brain development.
Topics: Aging; Animals; Animals, Newborn; Brain; Contrast Media; Image Enhancement; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Manganese; Mice | 2004 |
Tissue heavy metal concentrations of stranded California sea lions (Zalophus californianus) in Southern California.
Topics: Aging; Animals; Arsenic; Cadmium; California; Copper; Environmental Monitoring; Female; Iron; Kidney; Lead; Liver; Male; Manganese; Mercury; Metals, Heavy; Molybdenum; Sea Lions; Sex Factors; Water Pollutants, Chemical; Zinc | 2007 |
Age-related decrease in axonal transport measured by MR imaging in vivo.
Topics: Aging; Algorithms; Animals; Axonal Transport; Brain; Brain Chemistry; Image Processing, Computer-Assisted; Kinetics; Magnetic Resonance Imaging; Male; Manganese; Olfactory Pathways; Rats; Rats, Sprague-Dawley | 2008 |
Postmitotic tissue selenium and manganese levels in alpha-lipoic acid-supplemented aged rats.
Topics: Aging; Animals; Antioxidants; Cerebrum; Dietary Supplements; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Manganese; Mitosis; Muscle, Skeletal; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Selenium; Thioctic Acid; Tissue Distribution | 2008 |
Manganese supplementation improves mineral density of the spine and femur and serum osteocalcin in rats.
Topics: Aging; Animals; Appetitive Behavior; Bone Density; Female; Femur; Manganese; Osteocalcin; Rats; Rats, Sprague-Dawley; Spine; Weight Gain | 2008 |
Compromised store-operated Ca2+ entry in aged skeletal muscle.
Topics: Aging; Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Line; Male; Manganese; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; ORAI1 Protein; Reproducibility of Results; Stromal Interaction Molecule 1; Synaptophysin | 2008 |
Managanese-induced biochemical changes in growing versus adult rats.
Topics: Aging; Animals; Biogenic Amines; Body Weight; Brain Chemistry; Liver; Male; Manganese; Metals; Neurotransmitter Agents; Rats; Tryptophan; Tyrosine | 1980 |
The effects of chronic manganese feeding on the activity of monoamine oxidase in various organs of the developing rat.
Topics: Aging; Animals; Benzylamines; Female; Manganese; Monoamine Oxidase; Organ Size; Proteins; Rats; Rats, Inbred Strains; Serotonin | 1982 |
Coupling between neurons of the developing rat neocortex.
Topics: Aging; Animals; Axonal Transport; Cerebral Cortex; Evoked Potentials; Fluorescent Dyes; In Vitro Techniques; Isoquinolines; Manganese; Neurons; Rats; Rats, Inbred Strains | 1983 |
Developmental changes of two distinct ribonuclease H activities from rat brain and characterization of these enzymes.
Topics: Aging; Animals; Cerebellum; Endonucleases; Magnesium; Manganese; Rats; Ribonuclease H; Ribonucleases | 1980 |
Involvement of sulfhydryl groups in cerebral cortical [3H]clonidine binding in developing rats.
Topics: 4-Chloromercuribenzenesulfonate; Aging; Animals; Cerebral Cortex; Clonidine; Dithiothreitol; Ethylmaleimide; Female; Kinetics; Male; Manganese; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1983 |
Age-related changes in activities of the superoxide dismutase enzymes in tissues of the sheep and the effect of dietary copper and manganese on these changes.
Topics: Aging; Animals; Copper; Diet; Kidney; Liver; Lung; Manganese; Muscles; Myocardium; Sheep; Superoxide Dismutase | 1984 |
Zinc, copper, manganese and gold content of the hair of infants.
Topics: Aging; Birth Weight; Body Height; Body Weight; Copper; Female; Gold; Hair; Humans; Infant, Newborn; Longitudinal Studies; Male; Manganese; Zinc | 1984 |
Brain manganese concentrations in human aging and Alzheimer's disease.
Topics: Adult; Aged; Aging; Alzheimer Disease; Brain Chemistry; Female; Half-Life; Humans; Infant; Infant, Newborn; Male; Manganese; Middle Aged; Neutron Activation Analysis | 1984 |
Superoxide dismutase activity and lipid peroxidation in the rat: developmental correlations affected by manganese deficiency.
Topics: Aging; Animals; Copper; Female; Growth; Lipid Peroxides; Male; Manganese; Mitochondria, Liver; Oxidation-Reduction; Pregnancy; Rats; Rats, Inbred Strains; Superoxide Dismutase; Weaning; Zinc | 1983 |
[Manganese metabolism in rats of various ages].
Topics: Aging; Animals; Female; Fetus; Gestational Age; Manganese; Maternal-Fetal Exchange; Milk; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Physiological variations of serum levels of copper, zinc, iron and manganese.
Topics: Adult; Aging; Circadian Rhythm; Copper; Female; Humans; Iron; Male; Manganese; Metals; Middle Aged; Pregnancy; Sex Factors; Time Factors; Zinc | 1983 |
[Diagnostic importance of the manganese content of cattle hair. 2. Manganese content of hair and its dependence on environmental factors].
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Cattle; Female; Hair; Humans; Manganese; Species Specificity | 1984 |
The regional distribution of monoamine oxidase activities towards different substrates: effects in rat brain of chronic administration of manganese chloride and of ageing.
Topics: Aging; Animals; Benzylamines; Brain; Chlorides; Clorgyline; Dopamine; Female; Male; Manganese; Manganese Compounds; Monoamine Oxidase; Rats; Selegiline; Serotonin; Tissue Distribution | 1981 |
The effects of lanthanum and manganese on excitation-contraction coupling in the newborn rabbit heart.
Topics: Aging; Animals; Animals, Newborn; Lanthanum; Manganese; Myocardial Contraction; Rabbits; Time Factors | 1983 |
The effects of chronic manganese chloride treatment expressed as age-dependent, transient changes in rat brain synaptosomal uptake of amines.
Topics: Aging; Animals; Biological Transport; Brain; Chlorides; Choline; Dopamine; Male; Manganese; Manganese Compounds; Norepinephrine; Organ Specificity; Rats; Serotonin; Synaptosomes | 1982 |
Chronic ingestion of Mn3O4 by rats: tissue accumulation and distribution of manganese in two generations.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Diet; Female; Iron; Male; Manganese; Manganese Compounds; Oxides; Particle Size; Pregnancy; Rats; Time Factors; Tissue Distribution | 1982 |
Activities of the mitochondrial NAD-linked isocitric dehydrogenase in different regions of the rat brain: changes in ageing and the effect of chronic manganese chloride administration.
Topics: Aging; Animals; Brain; Cerebellum; Cerebral Cortex; Chlorides; Female; Hypothalamus; Isocitrate Dehydrogenase; Male; Manganese; Manganese Compounds; Medulla Oblongata; Mesencephalon; Mitochondria; Pons; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
Monoamine oxidase activities in liver, heart, spleen and kidney of the rat. Organ-specific changes in aging and after chronic manganese chloride administration.
Topics: Aging; Animals; Benzylamines; Chlorides; Heart; Isoenzymes; Kidney; Liver; Manganese; Manganese Compounds; Monoamine Oxidase; Myocardium; Organ Specificity; Rats; Rats, Inbred Strains; Serotonin; Spleen | 1982 |
Environmentally acquired lead, cadmium, and manganese in the cattle egret, Bubulcus ibis, and the laughing gull, Larus atricilla.
Topics: Aging; Animals; Birds; Cadmium; Female; Gastric Mucosa; Humans; Lead; Male; Manganese; Metals; Sex Factors; Tissue Distribution | 1980 |
Regulation of superoxide dismutase activity by dietary manganese.
Topics: Aging; Animals; Copper; Cyanides; Dose-Response Relationship, Drug; Female; Liver; Manganese; Metalloproteins; Mice; Rats; Species Specificity; Superoxide Dismutase; Zinc | 1980 |
Chronic manganese oxide administration to preweanling rats: manganese accumulation and distribution.
Topics: Aging; Animals; Body Weight; Female; Iron; Lethal Dose 50; Manganese; Manganese Poisoning; Organ Size; Pregnancy; Rats; Tissue Distribution | 1980 |
Age-related retention and distribution of ingested Mn3O4 in the rat.
Topics: Aging; Animals; Brain; Chemical Phenomena; Chemistry; Female; Liver; Male; Manganese; Particle Size; Rats; Time Factors; Tissue Distribution | 1980 |
The influence of color, age, and sex on the content of zinc, copper, nickel, manganese, and lead in human hair.
Topics: Adolescent; Adult; Aging; Child; Chromatography, High Pressure Liquid; Copper; Female; Hair; Hair Color; Humans; Lead; Male; Manganese; Nickel; Sex Characteristics; Trace Elements; Zinc | 1994 |
[Age and sex dependent variation in the content of Fe, Zn, Cu and Mn in different body parts and their retention in fattening pigs].
Topics: Aging; Animals; Copper; Female; Iron; Male; Manganese; Meat; Muscle, Skeletal; Sex Characteristics; Swine; Trace Elements; Viscera; Zinc | 1994 |
Brain regional distributions of monoamine oxidase activities in postnatal development in normal and chronically manganese-treated rats.
Topics: Aging; Animals; Animals, Newborn; Brain; Isoenzymes; Male; Manganese; Mitochondria; Monoamine Oxidase; Osmolar Concentration; Rats; Rats, Wistar; Reference Values; Synaptosomes; Time Factors; Tissue Distribution | 1993 |
Early postnatal development of thyrotropin-releasing hormone (TRH) expression, TRH receptor binding, and TRH responses in neurons of rat brainstem.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Brain Stem; Electric Stimulation; Female; Immunohistochemistry; In Situ Hybridization; In Vitro Techniques; Male; Manganese; Membrane Potentials; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Thyrotropin-Releasing Hormone; RNA, Messenger; Tetrodotoxin; Thyrotropin-Releasing Hormone; Tritium | 1994 |
Abdominal position of the rat testis is associated with high level of lipid peroxidation.
Topics: Aging; Animals; Blotting, Northern; Catalase; Cryptorchidism; DNA Probes; Gene Expression; Lipid Peroxidation; Male; Manganese; Nucleic Acid Hybridization; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Testis | 1995 |
Influence of season and diet on liver and kidney content of essential elements and heavy metals in Svalbard reindeer.
Topics: Aging; Animal Feed; Animals; Cadmium; Copper; Diet; Eating; Female; Kidney; Lead; Liver; Male; Manganese; Reindeer; Seasons; Selenium; Svalbard; Tissue Distribution; Trace Elements; Zinc | 1996 |
Effect of age and dietary protein level on tissue mineral levels in female rats.
Topics: Aging; Analysis of Variance; Animals; Calcium; Copper; Dietary Proteins; Female; Iron; Magnesium; Manganese; Phosphorus; Potassium; Rats; Rats, Wistar; Spectrophotometry, Atomic; Sulfur; Tissue Distribution; Zinc | 1996 |
Changes in superoxide dismutase activity in liver and lung of old rats.
Topics: Aging; Amino Acids; Animals; Liver; Lung; Male; Manganese; Rats; Rats, Wistar; Superoxide Dismutase | 1996 |
Age-related changes of the globular substance in the otoconial membrane of mice.
Topics: Acoustic Maculae; Aging; Aniline Compounds; Animals; Calcium; Fluorescent Dyes; Hair Cells, Vestibular; Ionomycin; Ionophores; Manganese; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microscopy, Confocal; Otolithic Membrane; Postural Balance; Saccule and Utricle; Sensation Disorders; Vestibule, Labyrinth; Xanthenes | 1997 |
Effect of swimming training on antioxidant enzymes in kidney of young and old mice.
Topics: Aging; Animals; Blotting, Northern; Catalase; Citrate (si)-Synthase; Copper; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxidase; Isoenzymes; Kidney; Male; Manganese; Mice; Muscle, Skeletal; Physical Conditioning, Animal; Random Allocation; RNA, Messenger; Superoxide Dismutase; Zinc | 1997 |
Reference values for the trace elements copper, manganese, selenium, and zinc in the serum/plasma of children, adolescents, and adults.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Copper; Humans; Infant; Manganese; Middle Aged; Reference Values; Selenium; Trace Elements; Zinc | 1997 |
Serum copper and ceruloplasmin activity at the early growing stage in foals.
Topics: Aging; Animals; Calcium; Ceruloplasmin; Copper; Embryonic and Fetal Development; Female; Fetal Blood; Horses; Male; Manganese; Oxidoreductases; Phosphates; Zinc | 1998 |
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Anti-Inflammatory Agents; Cerebellum; Colforsin; Dexamethasone; Fluorides; Glucocorticoids; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kidney; Male; Manganese; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Age-related functional and structural changes in human dermo-epidermal junction components.
Topics: Adolescent; Adult; Aged; Aging; Antigens, CD; Calcium; Cell Adhesion; Cells, Cultured; Child; Collagen; Dermis; Epidermis; Female; Humans; Integrin beta1; Integrin beta4; Keratinocytes; Laminin; Manganese; Microscopy, Immunoelectron; Middle Aged | 1998 |
Influence of age, sex and cross on body concentrations of trace elements (zinc, iron, copper and manganese) in chickens.
Topics: Aging; Animals; Body Composition; Body Weight; Chickens; Copper; Female; Iron; Male; Manganese; Sex Characteristics; Species Specificity; Trace Elements; Zinc | 1998 |
Manganese uptake into rat brain during development and aging.
Topics: Aging; Animals; Biological Transport; Brain; Chlorides; Liver; Male; Manganese; Manganese Compounds; Organ Specificity; Radioisotope Dilution Technique; Rats; Rats, Wistar; Tissue Distribution | 1999 |
Adolescent nicotine exposure alters cardiac autonomic responsiveness: beta-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Autonomic Nervous System; Carbachol; Cardiotonic Agents; Colforsin; Heart Conduction System; Isoproterenol; Manganese; Myocardium; Nicotine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Adrenergic, beta; Receptors, Muscarinic | 2000 |
Glutamate and catabolites of high-energy phosphates in the striatum and brainstem of young and aged rats subchronically exposed to manganese.
Topics: Aging; Animals; Brain Stem; Corpus Striatum; Energy Metabolism; Glutamic Acid; Hypoxanthine; Male; Manganese; Osmolar Concentration; Phosphates; Rats; Rats, Wistar; Time Factors; Uric Acid; Xanthine | 2000 |
Glutathione deficiency potentiates manganese-induced increases in compounds associated with high-energy phosphate degradation in discrete brain areas of young and aged rats.
Topics: Aging; Animals; Antimetabolites; Ascorbic Acid; Brain; Buthionine Sulfoximine; Dehydroascorbic Acid; Drug Synergism; Energy Metabolism; Glutathione; Hypoxanthine; Inosine; Male; Manganese; Phosphates; Rats; Rats, Wistar; Tissue Distribution; Uric Acid; Xanthine | 2000 |
Multi-element analysis of trace element levels in human autopsy tissues by using inductively coupled atomic emission spectrometry technique (ICP-AES).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cerebellum; Chromium; Cobalt; Copper; Female; Frontal Lobe; Humans; Iron; Kidney; Liver; Male; Manganese; Middle Aged; Myocardium; Ovary; Pancreas; Postmortem Changes; Quality Control; Selenium; Sex Characteristics; Spectrophotometry; Spleen; Time Factors; Trace Elements; Zinc | 2002 |
Differential regulation of glutamic acid decarboxylase mRNA and tyrosine hydroxylase mRNA expression in the aged manganese-treated rats.
Topics: Aging; Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Astrocytes; Avian Proteins; Basigin; Blood Proteins; Corpus Striatum; Gene Expression Regulation, Enzymologic; Glial Fibrillary Acidic Protein; Globus Pallidus; Glutamate Decarboxylase; Immunohistochemistry; Isoenzymes; Male; Manganese; Membrane Glycoproteins; Neurons; Nucleus Accumbens; Rats; Rats, Wistar; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2002 |
Age-dependent alterations of the rate of RNA synthesis in rat brain cell nuclei.
Topics: Age Factors; Aging; Animals; Brain; Cell Nucleus; Cerebral Cortex; DNA-Directed RNA Polymerases; Enzyme Activation; Histocytochemistry; Magnesium; Male; Manganese; Rats | 1977 |
Characterization of rat testicular guanylate cyclase during development.
Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Cyclic GMP; Enzyme Activation; Guanosine Triphosphate; Guanylate Cyclase; Kinetics; Male; Manganese; Polyethylene Glycols; Rats; Testis | 1979 |
Cyclic nucleotide phosphodiesterase activities of pig coronary arteries.
Topics: Aging; Animals; Cadmium; Calcium; Chelating Agents; Chromatography, DEAE-Cellulose; Coronary Vessels; Cyclic AMP; Enzyme Activation; Kinetics; Magnesium; Manganese; Muscle Proteins; Phosphoric Diester Hydrolases; Plants; Subcellular Fractions; Swine | 1975 |
Udp-galactose: glycoprotein galactosyltransferase activity in a clonal line of rat brain.
Topics: Aging; Animals; Brain; Calcium; Cell Line; Clone Cells; Dithiothreitol; Galactose; Glioma; Glycoproteins; Hexosyltransferases; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Neurons; Rats; Uridine Diphosphate Sugars | 1975 |
The distribution and accumulation of Cd, Zn, Pb, Cu, Co, Ni, Mn and K in human teeth from five different geological areas of Finland.
Topics: Adolescent; Adult; Aged; Aging; Cadmium; Child; Cobalt; Copper; Finland; Geological Phenomena; Geology; Humans; Lead; Manganese; Middle Aged; Nickel; Potassium; Tooth; Trace Elements; Zinc | 1979 |
Decreased long-term retention of 115mCd in Japanese quail produced by a combined supplement of zinc, copper, and manganese.
Topics: Aging; Animals; Cadmium; Copper; Coturnix; Female; Male; Manganese; Organ Specificity; Quail; Radioisotopes; Sex Factors; Time Factors; Tissue Distribution; Zinc | 1978 |
Levels of lead and other metals in human blood: suggestive relationships, determining factors.
Topics: Adolescent; Adult; Aging; Child; Female; Humans; Lead; Male; Manganese; Metals; Middle Aged; Occupational Diseases; Smoking; Socioeconomic Factors; Spectrophotometry, Atomic | 1978 |
Scanning electron microscope x-ray analysis of Ca, P, Fe, Si, K, Na, Mg, Zn, Co and Mn in the wall of the young and the old (atherosclerotic) aorta.
Topics: Aged; Aging; Aorta; Arteries; Arteriosclerosis; Calcium; Child, Preschool; Cobalt; Elements; Humans; Iron; Magnesium; Male; Manganese; Phosphorus; Potassium; Silicon; Sodium; Zinc | 1977 |
Calcium content of river water, trace element concentrations in toenails, and blood pressure in village populations in New Guinea.
Topics: Adolescent; Adult; Aging; Aluminum; Blood Pressure; Calcium; Female; Humans; Male; Manganese; Middle Aged; Nails; New Guinea; Toes; Vanadium; Water; Water Supply | 1976 |
Phosphoglycerate kinase from young and old Turbatrix aceti.
Topics: Aging; Animals; Calcium; Drug Stability; Hot Temperature; Kinetics; Magnesium; Manganese; Molecular Weight; Nematoda; Phosphoglycerate Kinase; Structure-Activity Relationship | 1976 |
The modifying effect of manganese on the enzymic profiles and pathways of carbohydrate metabolism in rat liver and adipose tissue during development.
Topics: Adipose Tissue; Aging; Animals; Carbohydrate Metabolism; Glucose; Glycolysis; Insulin; Lipids; Liver; Manganese; Rats | 1975 |
RNA polymerade activity in various classes of nuclei from different regions of rat brain during postnatal development.
Topics: Aging; Animals; Brain; Brain Stem; Cell Nucleus; Centrifugation, Zonal; Cerebellum; DNA-Directed RNA Polymerases; Enzyme Activation; Magnesium; Manganese; Organ Specificity; Rats | 1975 |
High levels of Mn-superoxide dismutase in serum of patients with neuroblastoma and in human neuroblastoma cell lines.
Topics: Adolescent; Aging; Bone Marrow; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Infant; Manganese; Neoplasm Recurrence, Local; Neuroblastoma; Reference Values; Superoxide Dismutase; Tumor Cells, Cultured; Wilms Tumor | 1992 |
Unusual accumulation of copper related to induction of metallothionein in the liver of LEC rats.
Topics: Aging; Animals; Copper; Electron Spin Resonance Spectroscopy; Hair Color; Iron; Kidney; Liver; Male; Manganese; Metallothionein; Organ Specificity; Rats; Rats, Mutant Strains; Reference Values; Superoxide Dismutase; Zinc | 1992 |
Effect of Mn2+ on neonatal and adult rat heart: initial depression and late augmentation of contractile force.
Topics: Aging; Animals; Animals, Newborn; Cardiotonic Agents; Drug Interactions; Manganese; Myocardial Contraction; Nicardipine; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum | 1992 |
Metalloproteinase activities expressed during development and maturation of the rat prostatic complex and seminal vesicles.
Topics: Aging; Animals; Animals, Newborn; Barium; Calcium; Caseins; Cobalt; Edetic Acid; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Magnesium; Male; Manganese; Metalloendopeptidases; Prostate; Rats; Rats, Sprague-Dawley; Seminal Vesicles; Strontium; Zinc | 1992 |
Transcriptional regulation of MnSOD by manganese in the liver of manganese-deficient mice and during rat development.
Topics: Aging; Animals; Animals, Newborn; Female; Hydrogen Peroxide; Liver; Manganese; Mice; Rats; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Transcription, Genetic | 1992 |
Plasma manganese levels in the very low birth weight infant are high in early life.
Topics: Adult; Aging; Enteral Nutrition; Female; Humans; Infant Food; Infant, Low Birth Weight; Infant, Newborn; Intensive Care, Neonatal; Male; Manganese; Milk, Human | 1992 |
Changes in brain regional manganese and magnesium levels during postnatal development: modulations by chronic manganese administration.
Topics: Aging; Animals; Body Water; Brain; Brain Chemistry; Diet; Female; Homeostasis; Magnesium; Manganese; Pregnancy; Rats; Rats, Inbred Strains | 1992 |
[A paradoxical increase in the Ca2+-binding capacity of the aortic wall in Wistar-Kyoto rats on a low Ca2+ content in the drinking water].
Topics: Aging; Animals; Aorta; Bone and Bones; Calcium; Drinking; Fluorescent Dyes; Male; Manganese; Myocardium; Rats; Rats, Inbred WKY; Spectrophotometry, Atomic | 1991 |
[Influence of zhuangling agent to metabolism of lipid in aged rats].
Topics: Acid Phosphatase; Aging; Animals; Cholesterol; Cholesterol, LDL; Deer; Drug Combinations; Lipid Metabolism; Lipoproteins, LDL; Manganese; Manganese Compounds; Materia Medica; Pollen; Rats; Rats, Inbred Strains; Sulfates; Superoxide Dismutase; Zinc; Zinc Sulfate | 1990 |
Mn2(+)-activated aspartate aminopeptidase activity, subcellular localization in young and adult rat brain.
Topics: Aging; Aminopeptidases; Animals; Brain; Cell Membrane; Glutamyl Aminopeptidase; Male; Manganese; Rats; Rats, Inbred Strains; Subcellular Fractions | 1990 |
Alterations of pancreatic digestive enzyme content in the manganese-deficient rat.
Topics: Aging; Amylases; Animals; Chymotrypsin; Lipase; Liver; Male; Manganese; Pancreas; Rats; Rats, Inbred Strains | 1987 |
[A FAAS analysis of seven elements and a preliminary exploration of their resistance to aging in huanjingjian oral liquid].
Topics: Aging; Drugs, Chinese Herbal; Iron; Manganese; Potassium; Rubidium; Spectrophotometry, Atomic; Zinc | 1989 |
Retention and distribution of manganese in the mouse brain following acute exposure on postnatal day 0, 7, 14 or 42: an autoradiographic and gamma counting study.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Brain; Manganese; Mice; Scintillation Counting; Tissue Distribution | 1989 |
Some factors influencing cadmium-manganese interaction in adult rats.
Topics: Aging; Animals; Cadmium; Drug Interactions; Duodenum; Female; Intestinal Mucosa; Intestines; Male; Manganese; Manganese Poisoning; Rats; Sex Factors | 1989 |
Effect of forced fasting on magnesium and manganese regulation in a terrestrial isopod, Porcellio spinicornis Say (Porcellionidae, Isopoda, Crustacea).
Topics: Aging; Animals; Crustacea; Diet; Fruit; Liver; Magnesium; Manganese; Pancreas | 1989 |
Effect of a metal mixture in diet on the toxicokinetics and toxicity of cadmium, mercury and manganese in rats.
Topics: Aging; Animals; Animals, Suckling; Cadmium; Diet; Drug Interactions; Female; Male; Manganese; Manganese Poisoning; Mercury; Metals; Rats; Rats, Inbred Strains | 1989 |
Phosphorylase phosphatase and phosphatase activating-kinase FA in growing rat muscles.
Topics: Aging; Animals; Cytosol; Enzyme Activation; Female; Glycogen; Insulin; Male; Manganese; Muscle Development; Muscles; Phosphoprotein Phosphatases; Phosphorylase Phosphatase; Protein Kinases; Protein Phosphatase 1; Rats; Rats, Inbred Strains; Trypsin | 1985 |
The effect of deficiencies of manganese and copper on osteoinduction and on resorption of bone particles in rats.
Topics: Aging; Animals; Bone and Bones; Bone Resorption; Copper; Diet; Female; Manganese; Osteogenesis; Rats; Rats, Inbred Strains; Time Factors; Trace Elements | 1987 |
Trace elements in nutrition of the elderly. 2. SADDIs for copper, manganese, selenium, chromium, molybdenum, and fluoride.
Topics: Aged; Aging; Chromium; Copper; Female; Fluorides; Humans; Male; Manganese; Middle Aged; Molybdenum; Nutritional Requirements; Selenium; Trace Elements | 1986 |
The effect of age on manganese uptake and retention from milk and infant formulas in rats.
Topics: Absorption; Aging; Animals; Animals, Newborn; Biological Availability; Cattle; Female; Infant Food; Manganese; Milk; Milk, Human; Pregnancy; Radioisotopes; Rats; Rats, Inbred Strains; Tissue Distribution | 1986 |
Properties of N-acetylhistamine deacetylase in mammalian brain.
Topics: Acetylation; Aging; Amidohydrolases; Animals; Brain; Cattle; Cricetinae; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; Kinetics; Male; Manganese; Mesocricetus; Mice; Mice, Inbred BALB C; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Swine; Thermodynamics; Tissue Distribution | 1985 |
Pyruvate carboxylase and phosphoenolpyruvate carboxykinase activity in developing rats: effect of manganese deficiency.
Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Female; Liver; Manganese; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Prenatal Exposure Delayed Effects; Pyruvate Carboxylase; Rats; Rats, Inbred Strains | 1985 |
The pathogenesis of amyotrophic lateral sclerosis.
Topics: Aging; Amyotrophic Lateral Sclerosis; Calcium; Central Nervous System; Central Nervous System Diseases; Environmental Exposure; Female; Humans; Japan; Male; Manganese; Micronesia; Middle Aged; Mining; Occupational Diseases; Sodium; Soil; Time Factors; Water Supply | 1972 |
[The use of micro-doses of copper and manganese in geriatrics].
Topics: Adrenocorticotropic Hormone; Aging; Animals; Copper; Insulin; Manganese; Mice; Rabbits; Rats | 1968 |
Effect of cold-storage of bean leaves on photosynthetic reactions of isolated chloroplasts. Inability to donate electrons to photosystem II and relation to manganese content.
Topics: Aging; Aniline Compounds; Benzene Derivatives; Biphenyl Compounds; Chloroplasts; Darkness; Diuron; Electron Transport; Hydroquinones; Hydroxylamines; In Vitro Techniques; Indophenol; Manganese; NADP; Phenols; Photosynthesis; Plants, Edible; Preservation, Biological; Semicarbazides; Spectrophotometry | 1972 |
Observations on the histochemical "aminopeptidase" reaction in the intestine of certain species of leech (Annelida: Hirudinea), with particular reference to Erpobdella octoculata (L.).
Topics: Aging; Aminopeptidases; Animals; Calcium; Chloromercuribenzoates; Cobalt; Copper; Cyanides; Edetic Acid; Enzyme Activation; Histocytochemistry; Hydrogen-Ion Concentration; Intestines; Lead; Leeches; Magnesium; Manganese; Propionates; Species Specificity; Zinc | 1972 |
[Age dynamics of certain macro- and microelements of the ligament apparatus of the spine].
Topics: Adult; Age Factors; Aged; Aging; Calcium; Copper; Humans; Ligaments; Manganese; Middle Aged; Spine; Zinc | 1972 |
Aeromonas aminopeptidase: purification and some general properties.
Topics: Aeromonas; Aging; Aminopeptidases; Calcium; Cellulose; Chromatography; Chromatography, Gel; Cobalt; Edetic Acid; Electrophoresis; Hydrogen-Ion Concentration; Magnesium; Manganese; Molecular Weight; Nickel; Ultracentrifugation; Zinc | 1966 |
The enzymic synthesis of ganglioside. II. UDP-galactose: N-acetylgalactosaminyl-(N-acetylneuraminyl)galactosyl-glucosyl-ceramide galactosyltransferase in rat brain.
Topics: Aging; Animals; Brain; Carbon Isotopes; Cell Nucleus; Edetic Acid; Fetus; Galactose; Gangliosides; Hydrogen-Ion Concentration; Manganese; Microsomes; Mitochondria; Myelin Sheath; Rats; Transaminases; Transferases | 1970 |
[The role of trace elements in the appearance of senile cataracts].
Topics: Aging; Cataract; Copper; Humans; Iron; Lens, Crystalline; Manganese; Trace Elements; Zinc | 1970 |
The enzymic synthesis of ganglioside. IV. UDP-N-acetylgalactosamine: (N-acetylneuraminyl)-galactosylglucosyl ceramide N-acetylgalactosaminyltransferase in rat brain.
Topics: Aging; Aluminum; Animals; Bile Acids and Salts; Brain; Carbon Isotopes; Cattle; Centrifugation; Cerebrosides; Chromatography, Gel; Chromatography, Paper; Copper; Detergents; Enzyme Activation; Gangliosides; Hexosamines; Humans; Hydrogen-Ion Concentration; Kidney; Kinetics; Lipidoses; Liver; Magnesium; Manganese; Microsomes; Mitochondria; Neuraminic Acids; Nickel; Nucleoside Diphosphate Sugars; Organ Specificity; Potassium; Rats; Solubility; Surface-Active Agents; Synaptic Membranes; Transferases; Uracil Nucleotides | 1971 |
Adrenergic innervation and cocaine-induced potentiation of adrenergic responses of aortic strips from young and old rabbits.
Topics: Aging; Animals; Aorta, Thoracic; Calcium; Cobalt; Cocaine; Cold Temperature; Drug Synergism; Histocytochemistry; Male; Manganese; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Phenylephrine; Pyrogallol; Rabbits; Receptors, Adrenergic; Reserpine; Tyramine | 1971 |
Inorganic cations in the crystalline lens from young and aged rats.
Topics: Age Factors; Aging; Aluminum; Animals; Calcium; Chromium; Cobalt; Copper; Female; Iron; Lens, Crystalline; Magnesium; Male; Manganese; Molybdenum; Nickel; Rats; Sex Factors; Strontium; Trace Elements; Zinc | 1968 |
Tocopherol, non-protein SH and metals in the human aorta.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Aorta; Arteriosclerosis; Calcium; Child; Copper; Humans; Lipids; Magnesium; Manganese; Metals; Middle Aged; Phospholipids; Statistics as Topic; Sulfhydryl Compounds; Vitamin E; Zinc | 1969 |