manganese(iii)tetraphenylporphine-sulfonate and Carcinoma
manganese(iii)tetraphenylporphine-sulfonate has been researched along with Carcinoma* in 1 studies
Other Studies
1 other study(ies) available for manganese(iii)tetraphenylporphine-sulfonate and Carcinoma
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A comparative study of manganese meso-sulfonatophenyl porphyrins: contrast-enhancing agents for tumors.
Four manganese meso-sulfonatophenyl porphyrins were prepared, characterized and investigated for their potential as tumor-specific MRI contrast-enhancing agents in mice bearing subcutaneous implants of a mammary carcinoma (SMT-F). The trisulfonated tetraphenyl porphyrin, MnTPPS3 presented the most favorable profile: bio-distribution, tumor concentration and tumor relaxivity, when compared at 24 hr postinjection. Imaging experiments revealed that a time-dependent delineation of tumor morphology occurs in response to MnTPPS3 that appears to correlate with necrotic regions of the tumor. Topics: Animals; Carcinoma; Drug Evaluation; Humans; Image Enhancement; Kidney; Liver; Magnetic Resonance Imaging; Mammary Neoplasms, Experimental; Metalloporphyrins; Mice; Muscles; Necrosis; Porphyrins; Time Factors; Tissue Distribution | 1990 |