maneb and Cocarcinogenesis

maneb has been researched along with Cocarcinogenesis* in 2 studies

Other Studies

2 other study(ies) available for maneb and Cocarcinogenesis

ArticleYear
Enhancement of tumor-initiating activity of DMBA by the carbamate fungicide mancozeb.
    Bulletin of environmental contamination and toxicology, 1990, Volume: 44, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Fungicides, Industrial; Maneb; Mice; Skin Neoplasms; Thiocarbamates; Zineb

1990
Tumour-promoting ability of mancozeb, a carbamate fungicide, on mouse skin.
    Carcinogenesis, 1988, Volume: 9, Issue:8

    In this study the tumour-promoting activity of a carbamate fungicide, mancozeb, has been observed following topical application on mouse skin in a two-stage initiation--promotion protocol for carcinogenesis. Female Swiss albino mice were initiated with a single subcarcinogenic dose (52 micrograms) of 7,12-dimethylbenz[a]anthracene painted on the interscapular region. Seven days after initiation the mice underwent topical application of mancozeb (100 mg/kg body wt) three times per week as promoter. Development of tumours was observed after 12 weeks of mancozeb application in 1/14 animals and 100% tumorigenesis was recorded after 17 weeks of mancozeb application. On histological examination, these tumours were found mostly to be benign in nature, e.g. squamous cell papillomas and keratocanthomas.

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Fungicides, Industrial; Maneb; Mice; Skin Neoplasms; Thiocarbamates; Zineb

1988