maltodextrin has been researched along with Influenza--Human* in 1 studies
1 other study(ies) available for maltodextrin and Influenza--Human
| Article | Year |
|---|---|
Deciphering molecular mechanics in the taste masking ability of Maltodextrin: Developing pediatric formulation of Oseltamivir for viral pandemia.
Present research work was aimed at masking the bitter taste of anti- viral drug Oseltamivir phosphate (Ost) by complexing it with pea starch maltodextrin- Kleptose Linecaps® (Mld). The Ost groups involved in triggering the bitter sensation were identified by computationally assessing its interaction with human bitter taste receptor hTAS2R 38. A series of exhaustive molecular dynamics (MD) simulation was run using Schrodinger® suite to understand the type of interaction of Ost with Mld. Experimentally, complexes of Ost with Mld were realized by solution method. The complexes were characterized using differential scanning colorimetry (DSC), fourier transform-infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), hot stage microscopy (HSM), scanning electron microscopy (SEM), proton NMR ( Topics: Aversive Agents; Drug Compounding; Female; Humans; Influenza, Human; Male; Molecular Dynamics Simulation; Oseltamivir; Polysaccharides; Solubility; Taste Perception; Young Adult | 2021 |