maltodextrin and Arthritis--Rheumatoid

maltodextrin has been researched along with Arthritis--Rheumatoid* in 1 studies

Other Studies

1 other study(ies) available for maltodextrin and Arthritis--Rheumatoid

Article	Year
Potential Privilege of Maltodextrin-α-Tocopherol Nano-Micelles in Seizing Tacrolimus Renal Toxicity, Managing Rheumatoid Arthritis and Accelerating Bone Regeneration. International journal of nanomedicine, 2021, Volume: 16 Tacrolimus (TAC) is a powerful immunosuppressive agent whose therapeutic applicability is confined owing to its systemic side effects.. Herein, we harnessed a natural polymer based bioconjugate composed of maltodextrin and α-tocopherol (MD-α-TOC) to encapsulate TAC as an attempt to overcome its biological limitations while enhancing its therapeutic anti-rheumatic efficacy.. The designed TAC loaded maltodextrin-α-tocopherol nano-micelles (TAC@MD-α-TOC) were assessed for their physical properties, safety, toxicological behavior, their ability to combat arthritis and assist bone/cartilage formation.. Overall, our designed bioconjugate micelles offered an excellent approach for improved TAC safety profile with enhanced anti-arthritic activity and unique bone formation characteristics. Topics: Animals; Arthritis, Rheumatoid; Bone Regeneration; Chlorocebus aethiops; Humans; Micelles; Nanostructures; Polysaccharides; Tacrolimus; Tocopherols; Vero Cells	2021

Article

Year

Potential Privilege of Maltodextrin-α-Tocopherol Nano-Micelles in Seizing Tacrolimus Renal Toxicity, Managing Rheumatoid Arthritis and Accelerating Bone Regeneration.

International journal of nanomedicine, 2021, Volume: 16

Tacrolimus (TAC) is a powerful immunosuppressive agent whose therapeutic applicability is confined owing to its systemic side effects.. Herein, we harnessed a natural polymer based bioconjugate composed of maltodextrin and α-tocopherol (MD-α-TOC) to encapsulate TAC as an attempt to overcome its biological limitations while enhancing its therapeutic anti-rheumatic efficacy.. The designed TAC loaded maltodextrin-α-tocopherol nano-micelles (TAC@MD-α-TOC) were assessed for their physical properties, safety, toxicological behavior, their ability to combat arthritis and assist bone/cartilage formation.. Overall, our designed bioconjugate micelles offered an excellent approach for improved TAC safety profile with enhanced anti-arthritic activity and unique bone formation characteristics.

Topics: Animals; Arthritis, Rheumatoid; Bone Regeneration; Chlorocebus aethiops; Humans; Micelles; Nanostructures; Polysaccharides; Tacrolimus; Tocopherols; Vero Cells

2021