maltitol has been researched along with Body-Weight* in 2 studies
2 other study(ies) available for maltitol and Body-Weight
| Article | Year |
|---|---|
Dietary maltitol decreases the incidence of 1,2-dimethylhydrazine-induced cecum and proximal colon tumors in rats.
Maltitol is fermented in the colon due to only partial hydrolysis in the small intestine. In the present study, we examined effects of dietary maltitol on dimethylhydrazine-induced intestinal tumor in rats. In experiment 1, rats were fed a fiber-free diet or diets supplemented with 1 or 5 g/100 g maltitol for 27 wk. Each group of rats was injected with dimethylhydrazine or vehicle alone for the first 14 wk of the experimental period. Maltitol supplementation at 1 g/100 g of the diet significantly reduced tumor incidence in the cecum and the 5% supplement reduced tumor incidence in both the cecum and proximal colon in dimethylhydrazine-treated rats. In experiment 2, we investigated the effect of the 1 g/100 g maltitol diet on the short chain fatty acid concentrations in cecal contents of placebo and dimethylhydrazine-treated rats. Intake of the 1 g/100 g maltitol diet doubled (P < 0.05) the concentration of butyrate but did not affect acetate or propionate in the cecal contents. These results suggest that dietary maltitol has a protective effect against dimethylhydrazine-induced tumors in rat cecum and proximal colon and that butyrate produced by bacterial fermentation of maltitol in the cecum may be involved in the protection. Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Cecal Neoplasms; Cecum; Colonic Neoplasms; Diet; Eating; Fatty Acids, Volatile; Gastrointestinal Contents; Hydrogen-Ion Concentration; Incidence; Male; Maltose; Rats; Rats, Inbred F344; Sugar Alcohols | 1998 |
Nutritional studies on maltitol. Part 1: Acceptability, energetic yield, effects on growth and blood biochemical parameters.
Maltitol is a disaccharide molecule with special physico-chemical characteristics due to a glycosidic bond which is not easily split by the natural disaccharidases. The present study was designed to evaluate the effects of a prolonged feeding with maltitol on growing rats. Acceptability, caloric yield, intestinal absorption and metabolic effects have been determined. Topics: Animals; Behavior, Animal; Blood Cell Count; Blood Urea Nitrogen; Body Weight; Eating; Male; Maltose; Rats; Sugar Alcohols; Sweetening Agents | 1984 |