malonyl-coenzyme-a and Protein-Energy-Malnutrition

malonyl-coenzyme-a has been researched along with Protein-Energy-Malnutrition* in 1 studies

Other Studies

1 other study(ies) available for malonyl-coenzyme-a and Protein-Energy-Malnutrition

Article	Year
Pre- and postnatal protein undernutrition increases hepatic carnitine palmitoyltransferase I activity and decreases enzyme sensitivity to inhibitors in the suckling rat. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1992, Volume: 24, Issue:10 Rats were pair-fed isocaloric diets containing either 25% (control diet) or 6% protein (low-protein diet) during the 5 weeks prior to conception and through the gestation and lactation periods; then, carnitine palmitoyltransferase I (CPT-I) activity was determined in liver and skeletal muscle mitochondria isolated from the corresponding pups. Maternal protein undernutrition increased the activity of hepatic CPT-I all along the suckling period, whereas the activity of the skeletal muscle enzyme was unaffected. Moreover, the sensitivity of hepatic CPT-I to inhibition by both malonyl-CoA and 4-hydroxyphenylglyoxylate was decreased in the low-protein group. These alterations in the properties of hepatic CPT-I may be involved in the appearance of hyperketonemia in the rat pup upon maternal administration of low-protein diets. Topics: Animals; Carnitine O-Palmitoyltransferase; Female; Glyoxylates; Kinetics; Lactation; Malonyl Coenzyme A; Maternal-Fetal Exchange; Mitochondria, Liver; Mitochondria, Muscle; Pregnancy; Pregnancy Complications; Protein-Energy Malnutrition; Rats; Rats, Wistar	1992

Article

Year

Pre- and postnatal protein undernutrition increases hepatic carnitine palmitoyltransferase I activity and decreases enzyme sensitivity to inhibitors in the suckling rat.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1992, Volume: 24, Issue:10

Rats were pair-fed isocaloric diets containing either 25% (control diet) or 6% protein (low-protein diet) during the 5 weeks prior to conception and through the gestation and lactation periods; then, carnitine palmitoyltransferase I (CPT-I) activity was determined in liver and skeletal muscle mitochondria isolated from the corresponding pups. Maternal protein undernutrition increased the activity of hepatic CPT-I all along the suckling period, whereas the activity of the skeletal muscle enzyme was unaffected. Moreover, the sensitivity of hepatic CPT-I to inhibition by both malonyl-CoA and 4-hydroxyphenylglyoxylate was decreased in the low-protein group. These alterations in the properties of hepatic CPT-I may be involved in the appearance of hyperketonemia in the rat pup upon maternal administration of low-protein diets.

Topics: Animals; Carnitine O-Palmitoyltransferase; Female; Glyoxylates; Kinetics; Lactation; Malonyl Coenzyme A; Maternal-Fetal Exchange; Mitochondria, Liver; Mitochondria, Muscle; Pregnancy; Pregnancy Complications; Protein-Energy Malnutrition; Rats; Rats, Wistar

1992